Clinical trials: Functional Outcomes
Sickle Cell Disease, Drepanocytosis
Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.
Sickle cell disease (SCD) is an inherited blood disorder. Symptoms include acute and chronic complications. Due to progress in SCD care, patients with SCD are living longer than before and we focus more attention in chronic…
- Trial name
- Drépa-COG (NCT04244240)
- Testing
- BEARNI Tool
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Hospices Civils de Lyon
Insomnia, Psychosis
CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes
The goal of this project is to develop guidelines for the clinical tailoring of Cognitive Behavioral Therapy for Insomnia (CBT-I) for Veterans with psychotic disorders and insomnia, and to test the acceptability, feasibility, and…
- Trial name
- CBT-I (NCT02535923)
- Testing
- Cognitive Behavioral Therapy-Insomnia, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Intensive Care Unit Acquired Weakness (ICUAW)
eStimCycle: Early Rehabilitation in Critical Care
Project Summary: Patients who have a length of stay four or more days in ICU and requiring mechanical ventilation assistance to breathe for more than 48 hours will be invited to participate.
- Trial name
- eStimCycle (NCT02214823)
- Testing
- FES-Cycling, Standard Care
- Where
- 4 sites in United States, Australia
- Volunteers
- 162 people
- Sponsor
- Associate Professor Sue Berney PhD, BPT
Soft Tissue Sarcoma
Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the…
- Trial name
- NCT06962072
- Testing
- Surgical resection with or without radiotherapy and/or chemotherapy
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Amsterdam UMC
Colorectal Cancer
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery.
- Trial name
- NCT07144475
- Testing
- Lactobacillus casei Shirota, Lactobacillus acidophilus
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Dharmais National Cancer Center Hospital
Cognitive Decline, Cognitive Impairment, Mild
Efficacy of a Mobile-based Multidomain Intervention to Improve Cognitive Function and Health-related Outcomes Among Older Korean Adults With a High Risk of Dementia
This study investigated the efficacy of the Silvia program, a mobile-based multidomain intervention, to improve cognitive function and health-related outcomes of older adults with a high risk of dementia.
- Conditions
- Cognitive Decline, Cognitive Impairment, Mild, Aging, Dementia
- Trial name
- NCT05675137
- Testing
- mobile-based, paper-based
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Silvia Health
Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
Optimised Cardiovascular and Renal Protection in Patients With Chronic Kidney Disease and Cardiovascular Disease
The goal of this clinical trial is to investigate whether care in a specialised Cardio-Renal Clinic can improve the health of people living with both cardiovascular disease and chronic kidney disease.
- Conditions
- Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF), Cardiovascular Diseases
- Trial name
- OPTICARE (NCT07835828)
- Testing
- Multidisciplinary Cardio-Renal Care
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Odense University Hospital
Colorectal Cancer
Supervised Versus Non-supervised Exercise on Adherence and Functional Outcomes in Colorectal Patients
Investigation into prehabilitation by increasing the supervision of exercise in patients undergoing colorectal resection for cancer and comparing with patients involved in a rehabilitation group receiving exercise after surgery.
- Trial name
- NCT02586701
- Testing
- Prehabilitation Plus
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Franco Carli
Physical Inactivity, Sedentariness
Effects of a School-Based Physical Activity Intervention on 24-Hour Movement Behaviours and Motor Development in Preschool Children - Study Protocol
This protocol describes a quasi-experimental controlled study evaluating the effects of the Super Quinas in Preschool programme on 24-hour movement behaviours and motor development in preschool children aged 3-6 years.
- Conditions
- Physical Inactivity, Sedentariness, Sleep, Motor Skills
- Trial name
- SQP (NCT07553507)
- Testing
- SuperQuinas in Preschool Programme
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- Lusofona University
Focal Hand Dystonia
Impact Of Physiotherapy And Botox In Improving Functional Outcomes Among Post Stroke Focal Dystonia Patients
This study was conducted to assess the combine role of Physiotherapy by providing task specific trainings and Botulinum Toxin Type A in improving the functional outcomes of upper limb in post stroke patients with focal hand…
- Trial name
- NCT03664375
- Testing
- Botulinum toxin type A, Task Specific Training
- Volunteers
- 39 people
- Sponsor
- Isra University
Multiple Sclerosis, Exercise
Impact of Exercise Training on Serum Glial Fibrillary Acidic Protein (GFAP), Brain Volumetry, and Functional Outcomes in Multiple Sclerosis
This single-blind, randomized controlled trial will employ a two-arm parallel design (exercise group vs. control group) with a 12-week intervention period.
- Conditions
- Multiple Sclerosis, Exercise, Function
- Trial name
- NCT07521995
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Septic Shock
Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock
This study has been approved as a nested substudy of a multicenter trial (CORVICTES, Clinicaltrials.gov Identifier: NCT03592693).
- Trial name
- CORVICTES-ΥΜ (NCT03649633)
- Testing
- Stress-dose Hydrocortisone plus Vitamin C
- Where
- Greece
- Volunteers
- 26 people
- Sponsor
- University of Athens
Gastrointestinal Function, Quality of Life
A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis
This retrospective study aims to compare the surgical and pregnancy outcomes of disc and segmental resection for rectal DIE through a single-center retrospective analysis, to summarize clinical experience, and to explore the…
- Conditions
- Gastrointestinal Function, Quality of Life, Pregnancy Outcomes
- Trial name
- NCT06254716
- Testing
- disc resection, segmental resection
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fudan University
Rehabilitation, Exercise Therapy
Rehabiliation Using HUBER 360 to Reduce the Risk of Falls
Aim: The aim of the present study was to analyse the effects of training performed on a rotating, motorised platform (the Huber/SpineForce device from LPG Systems, Valence, France) intended to reduce the risk of falls.
- Conditions
- Rehabilitation, Exercise Therapy, Treatment Outcome, Quality of Life
- Trial name
- HUBER-FALLS (NCT04687293)
- Testing
- HUBER (LPG Systems, France)
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- University of Liege
Limb-girdle Muscular Dystrophy
A Study of the Natural History of Participants With LGMD2E/R4, LGMD2D/R3, LGMD2C/R5, and LGMD2A/R1 ≥ 4 Years of Age, Who Are Managed in Routine Clinical Practice
This study will follow participants who are screened and confirmed with a genetic diagnosis of Limb-girdle muscular dystrophy type 2E (LGMD2E/R4), Limb-girdle muscular dystrophy type 2D (LGMD2D/R3), Limb-girdle muscular dystrophy…
- Trial name
- NCT04475926
- Where
- 26 sites in United States, Belgium and 8 more
- Volunteers
- 205 people
- Sponsor
- Sarepta Therapeutics, Inc.
Geriatric Hip Fracture
'Home Sweet Home' Programme-2
Objectives: To determine the effectiveness of telerehabilitation on the quality of life and mobility of early post-discharge in hip fracture patients, and to investigate whether telerehabilitation in the form of daily TUG tests…
- Trial name
- NCT05823129
- Testing
- Tele-rehabilitation caregiver empowerment enhanced post- discharge rehabilitation directive
- Where
- Hong Kong
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acute Stroke
Evaluation of Physical Therapy Interventions and Patient Characteristics on Outcomes
Data collection for this study will be done by clinicians working in inpatient rehabilitation units with persons with acute stroke. No interventions are included in this study.
- Trial name
- PBE (NCT02098083)
- Where
- 4 sites in United States
- Sponsor
- University of Texas Southwestern Medical Center
Total Hip Arthroplasty, Osteoarthritis
Improving Rehabilitation Outcomes After Total Hip Arthroplasty
This study plans to learn more about the effects of physical therapy (PT) following a total hip arthroplasty (THA). The purpose of this study is to compare standard of care PT after THA with a physical therapy program…
- Trial name
- NCT02920866
- Testing
- Functional Strength Integration (FSI), Control Group (CON)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- VA Office of Research and Development
Osteoarthritis, Knee
WATERinMOTION Aquatic Therapy in Obese Men With Knee Osteoarthritis
This RCT evaluates whether WATERinMOTION aquatic therapy improves pain, function, and quality of life more effectively than land-based exercise in obese men with knee osteoarthritis (OA).
- Conditions
- Osteoarthritis, Knee, Obesity
- Trial name
- WATERinMOTION (NCT06946329)
- Testing
- Aquatic Exercise, Land-Based Rehabilitation
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- University of Sistan and Baluchestan