Clinical trials: Functional Somatic Disorder
Irritable Bowel Syndrome, Inflammatory Bowel Disease
25-hydroxyvitamin D and Fatigue: The VITALITY Study
The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome.
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Disease, Diabetes, Rheumatoid Arthritis
- Trial name
- NCT01718925
- Volunteers
- 614 people
- Sponsor
- Ostfold Hospital Trust
Somatic Symptom Disorder
Reappraisal Of Medical Assurance (ROMA): An Experimental Study in Patients With Functional Somatic Symptoms
Research has shown that patients with functional somatic symptoms continue to worry about having a serious disease despite medical reassurance from their doctors.
- Trial name
- ROMA (NCT04044469)
- Testing
- Immunization-enhancement, Immunization-inhibition, Control group
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Philipps University Marburg
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Somatization Disorder, Somatoform Disorders
Acceptance and Commitment Group Therapy for Adolescents With a Range of Functional Somatic Syndromes
Background: An increasing number of adolescents report recurrent functional somatic symptoms. Some experience persistent symptoms and may receive functional somatic syndromes (FSS) diagnoses (i.e.
- Trial name
- NCT02346071
- Testing
- Acceptance and Commitment Therapy, Enhanced Usual Care (EUC)
- Where
- Denmark
- Volunteers
- 91 people
- Sponsor
- University of Aarhus
Somatoform Disorders, Globus Hystericus
Treatment of Globus Sensations With Psychotherapy
The purpose of this study is to determine whether psychotherapy (based on exposure techniques) is effective in the treatment of functional somatic symptoms (FSS)/Somatoform Disorders (as exemplified here in subjects with globus…
- Trial name
- NCT01590992
- Testing
- Exposure-based psychotherapy for somatic symptoms, Relaxation therapy
- Where
- Switzerland
- Volunteers
- 175 people
- Sponsor
- University Hospital, Basel, Switzerland
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Somatization Disorder, Functional Disorders
Mindfulness-based Cognitive Therapy for Patients With Functional Disorders
The aim of the study is to examine the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) in patients with functional disorders defined as severe Bodily Distress Disorder.
- Conditions
- Somatization Disorder, Functional Disorders, Bodily Distress Disorder
- Trial name
- NCT00497185
- Testing
- Mindfulness-Based Cognitive Therapy for Functional Disorders
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Aphasia, Development, Human
Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective
The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population.
- Conditions
- Aphasia, Development, Human, Neuropathology
- Trial name
- NCT06365658
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Somatic Symptom and Related Disorders, Somatic Symptom Disorder
Telehealth Group-based Emotional Awareness and Expression Therapy for Patients With Persistent Physical Symptoms: A Pilot Study
Delivering Emotional Awareness and Expression Therapy (EAET) through digital or telehealth platforms in a group format offers several key advantages.
- Conditions
- Somatic Symptom and Related Disorders, Somatic Symptom Disorder, Functional Somatic Disorder, Functional Somatic Syndrome
- Trial name
- NCT06631963
- Testing
- Emotional Awareness and Expression Therapy
- Where
- Sweden
- Sponsor
- Daniel Maroti
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery
A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have…
- Trial name
- PRP NG PRO M (NCT07188064)
- Testing
- Post radical prostatectomy nerve restoration procedure (PRP-NR)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Functional Disorder, Bodily Distress Syndrome
Central Processing of Odour Stimuli in Patients With Functional Somatic Disorder, MCS or Post Covid Compared to Healthy Controls
Background: Functional somatic disorders (FSD) are frequent in all medical settings and characterized by persistent physical symptoms that cannot be explained by other somatic or psychiatric conditions.
- Conditions
- Functional Disorder, Bodily Distress Syndrome, Multiple Chemical Sensitivity, Post COVID-19
- Trial name
- NCT04935307
- Testing
- MRI and paraclinical tests
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Vertigo, Dizziness
Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo
Western University of Health Sciences is seeking men and women to participate in a study on the effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in patients with vertigo.
- Conditions
- Vertigo, Dizziness, Benign Paroxysmal Positional Vertigo, Labyrinthitis
- Trial name
- NCT01529151
- Testing
- Osteopathic Manipulative Treatment (OMT), Vestibular Rehabilitation Therapy (VRT)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Work Related Stress
Somatic Psychoeducational Intervention
The goal of this clinical trial is to explore possible benefits and mechanisms through which the Somatic Psychoeducational Intervention can improve health and wellness.
- Trial name
- NCT06580119
- Testing
- Somatic Psychoeducational Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Irritable Bowel Syndrome, Fibromyalgia
Psychological Risk Factors for Functional Somatic Disorders
The objective of this study is to explore the role of neuroticism, perceived stress, and adverse life events, respectively, in the development and perpetuation of functional somatic disorders.
- Conditions
- Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome, Somatoform Disorders
- Trial name
- NCT05631860
- Volunteers
- 7,493 people
- Sponsor
- University of Aarhus
Bodily Distress Syndrome, Functional Somatic Disorder
DISTRESS Trial Functional Disorders - the DISTRESS Trial
A Diagnostic Clinic for Functional Somatic Disorders (FSD) has been set up at the outpatient diagnostic center at Regionshospitalet Silkeborg.
- Trial name
- DISTRESS (NCT06025617)
- Testing
- Diagnostic evaluation at the Diagnostic Clinic for Functional Disorders, Diagnostic as usual
- Where
- Denmark
- Volunteers
- 290 people
- Sponsor
- Regionshospitalet Silkeborg
Persistent Physical Symptoms (PPS), Functional Somatic Disorder
Emotional Awareness and Expression Therapy for Patients With Persistent Physical Symptoms in Routine Psychiatric Care: A Pilot Study
Emotional Awareness and Expression Therapy (EAET) has emerged as a promising approach for addressing persistent physical symptoms (PPS).
- Conditions
- Persistent Physical Symptoms (PPS), Functional Somatic Disorder, Functional Somatic Syndromes, Somatic Symptom Disorder (DSM-5)
- Trial name
- EAET for PPS (NCT06631911)
- Testing
- Emotional Awareness and Expression Therapy (EAET)
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Daniel Maroti
Platinum Sensitive Relapsed Ovarian Cancer
Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations
Olaparib administered as monotherapy in the maintenance setting improves progression free survival compared to placebo in patients whose tumours carry loss of function (deleterious or suspected deleterious) somatic BRCA mutations…
- Trial name
- NCT02392676
- Testing
- OLAPARIB
- Where
- 29 sites in United States, Peru and 3 more
- Sponsor
- AstraZeneca
Fibromyalgia, Irritable Bowel Syndrome
Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study
This cohort study implements patient reported outcome measures (PROMs) for patients with bodily stress syndrome in a clinic for functional disorders.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Somatic Symptom, Chronic Fatigue Syndrome
- Trial name
- SYMPA (NCT04667611)
- Testing
- Psychosocial interventions
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital