Clinical trials: Functional Urinary Incontinence
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Urinary Incontinence, Sexual Dysfunction
The Mindfulness, Incontinence and Sexual Function Treatment Study
This study aims to determine if there is an impact on sexual distress using mindfulness-based sex therapy (MBST) in addition to standard urogynecologic care, in women with both urinary incontinence (UI) and sexual dysfunction.
- Trial name
- MIST (NCT02863497)
- Testing
- Mindfulness-based Sex Therapy
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Urinary Incontinence, Sarcopenia
The Urinary Incontinence Treatment Study
Investigators plan a prospective cohort study with an adaptive design based on physical function status. The design will involve tracking the number of women recruited with physical function impairment and those without any…
- Trial name
- UNITS (NCT03057834)
- Testing
- Pelvic floor muscle exercise
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy
This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- MPE-RP (NCT07520916)
- Testing
- Mobile-Based Perioperative Education Program, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Giresun University
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Urinary Incontinence, Menopause
Testosterone Effects on Pelvic Floor Muscles
An proof-of-concept study to determine whether administration of testosterone enanthate weekly results in greater improvements in structural and functional characteristics of pelvic floor muscles and urodynamic parameters in…
- Trial name
- TPELVIC (NCT04026880)
- Testing
- Testosterone Enanthate
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Urinary Incontinence, Stress Urinary Incontinence
Efficacy of the Use of Vaginal Balls for the Improvement of Urinary Incontinence and Sexual Function in Women.
Asess if adding vaginal spheres treatment to the conventional Pelvic Floor Muscle Trainning (PFMT) produces a greater decrease in the severity of the stress urinary incontinence or a greater perceived quality of life related to…
- Conditions
- Urinary Incontinence, Stress Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT05732844
- Testing
- Intervention group with Enna pelvic ball, Control group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- RAPbarcelona
Urinary Incontinence, Urge, Urinary Incontinence
TReating Incontinence for Underlying Mental and Physical Health
The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder…
- Conditions
- Urinary Incontinence, Urge, Urinary Incontinence, Overactive Bladder, Incontinence, Urge
- Trial name
- TRIUMPH (NCT05362292)
- Testing
- Tolterodine Tartrate ER, Mirabegron
- Where
- 2 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Multiple Sclerosis, Disabilities Multiple
The Relationship of Neuropathic Pain With Incontinence, Disability and Life Quality in Multiple Sclerosis Patients
The aim of this study to evaluate the relationship of neuropathic pain with urinary and bowel incontinence, functional disability and quality of life in patients with multiple sclerosis.
- Conditions
- Multiple Sclerosis, Disabilities Multiple, Quality of Life, Incontinence, Urinary
- Trial name
- NCT05374811
- Testing
- Neuropathic Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Incontinence, Stress
Evaluation Of A Novel Methodology In The Assessment Of Urethral Function Using SS-RBX.
SS-RBX will be used to evaluate pharmacodynamic changes in urethral function using a novel methodology
- Trial name
- NCT00141128
- Testing
- SS-RBX
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Pfizer
Urge Urinary Incontinence
Incontinence & Intimate Partners: Assessing the Contribution of Treatment
Urge urinary incontinence (UUI) is a socially debilitating disease due to its inherently unpredictable nature and sometimes large volumes of urine loss.
- Trial name
- IIMPACT (NCT01559389)
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Loyola University
Genitourinary Syndrome of Menopause
Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients
Genitourinary Syndrome of Menopause (GSM), characterized by vaginal dryness, pain, urinary incontinence, and other symptoms, can be mitigated through both hormonal and non-hormonal treatments.
- Trial name
- Maicol (NCT07151482)
- Testing
- Collagendep
- Volunteers
- 43 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prostate Cancer
Salvage Radiotherapy After Radical Prostatectomy
The purpose of this study is to describe the urinary morbidity as a result surgery and radiation therapy, in patients treated for prostate cancer.
- Trial name
- SRT (NCT02597725)
- Volunteers
- 70 people
- Sponsor
- University of Aarhus
Urinary Incontinence, Pelvic Floor Muscle Weakness
Dose-response of Physical Exercise on Pelvic Floor Muscle Function in Postmenopausal Women With Urinary Incontinence
Urinary incontinence (UI) symptoms are highly prevalent among women, and menopause is one of the risk factors for UI. During the menopausal transition, not only the hormonal secretion is changed but also the level of physical…
- Trial name
- NCT04351750
- Testing
- general exercise, pelvic floor muscle training
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- National Cheng Kung University
Stress Urinary Incontinence, Fecal Incontinence
Effects of Single Dose Citalopram and Reboxetine on Urethral and Anal Closure Function on Healthy Female Subjects
This study will investigate if citalopram, a selective serotonin reuptake inhibitor, is reducing the opening pressure of the urethra and possibly causing or worsening stress urinary incontinence.
- Trial name
- NCT04097288
- Testing
- Citalopram 40mg, Reboxetine 8 mg
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Urinary Incontinence (UI), Urinary Incontinence , Stress
Difference in Incontinence Prevalence Between High Impact Athletes, Low Impact Athletes and Sedentary Subjects
This observational cross-sectional study aims to investigate the association between participation in high-impact sports, physical activity level, and urinary incontinence in young adults.
- Trial name
- NCT07710508
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Quality of Life, Sexual Function
Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial
Quality of life after rectal surgery is reported to be impaired. Side effects of surgery and/or neoadjuvant treatment as functional disturbances like sexual dysfunction, urinary incontinence, anal incontinence or stoma problems…
- Conditions
- Quality of Life, Sexual Function, Urinary Incontinence, Anal Incontinence
- Trial name
- NCT00895388
- Testing
- Structured Rehabilitation program
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Spinal Cord Injury, Neurogenic Bladder
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation. The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder, Incontinence
- Trial name
- NCT02978638
- Testing
- Finetech Vocare Bladder System
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Palo Alto Veterans Institute for Research
Quality of Life, Sexual Dysfunction
Benign Prostate Surgery and QOL and Sexual Function
Rationale: A variety of surgical techniques have been described for surgical treatment of male LUTS because of BPH, which has different outcomes and may result in adverse events regarding ejaculatory function and erection…
- Conditions
- Quality of Life, Sexual Dysfunction, Ejaculatory Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- BEPS (NCT05826691)
- Testing
- Monopolar / Bipolar Transurethral resection of prostate (TURP), photovaporisation (PVP), Plasmakinetic (PK), Holmium laser enucleation of the prostate (HOLEP) or open prostatectomy (OP)).
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Istanbul Medipol University Hospital