Clinical trials: Functioning
Healthy Individuals With Hamstring Tightness
The Immediate Effects Of Thoracolumbar Fascia Inhibition And Suboccipital Muscle Inhibition
This randomized controlled trial aimed to compare the immediate effects of two self-myofascial release techniques-suboccipital muscle inhibition and thoracolumbal fascia inhibition-on hamstring flexibility, spinal range of…
- Trial name
- NCT07096076
- Testing
- Thoracolumbar fascia inhibition, Suboccipital inhibition group, hamstring stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Erector Spina Plan Block, Echocardiography
Effect of Left Erector Spinae Plane Block on Left Ventricular Functions
Many studies have shown a decrease in inotropic status (intrinsic function) after blockade of cardiac sympathetic innervation with thoracic epidural anesthesia (TEA) (4,5).
- Trial name
- ESP-LV ECHO (NCT06770816)
- Testing
- Echocardiography
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Low Back Pain, Postural
Functional Pathologies of the Musculoskeletal System in Physiotherapy Students
This study map the occurrence of functional pathologies of the musculoskeletal system in students of the bachelor's program of physiotherapy of the Third Faculty of Medicine, Charles University, and aim on improvement of them.
- Trial name
- FUNPAMUS (NCT05544188)
- Testing
- Differential diagnostic
- Where
- Czechia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Vitamin D Deficiency
Immunologic Action of a Single Dose Cholecalciferol
Vitamin D receptors are expressed in activated different immune cells. It is not known, which immune cell type is targeted by exogenous vitamin D. Here, vitamin D-deficient individuals will receive once 100.000 I.U.
- Trial name
- ViDImmun (NCT01845142)
- Testing
- single administration of 100.000 I.U. vitamin D
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Margitta Worm
Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion
New Non-invasive Modalities for Assessing Retinal Structure and Function
This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other…
- Conditions
- Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy
- Trial name
- NCT03475173
- Testing
- LSFG-NAVI
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Tennis Elbow, Epicondylitis, Lateral Humeral
Relationships Between Ultrasound Data and the Impact of Lateral Epicondylar Pain
Our primary objective is to study the relationship between ultra sound data and the pain associated with tennis elbow.
- Trial name
- EPICORE (NCT01390454)
- Testing
- Ultrasound of the elbow 1, days 7 to 15, Ultrasound of the elbow 2, days 7 to 15, Ultrasound of the elbow 3, days 45 to 90
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke
A Longitudinal Study of Function and Participation in Patients With Stroke
A longitudinal study of function and participation in patients with stroke: An integrated brain imaging and biomechanical analysis
- Trial name
- NCT02377453
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Brain Tumors
Presurgical Planning With Functional MRI (fMRI) Mapping of Motor Cortex in Patients With Cerebral Tumors
The purpose of this study is to determine if functional MRI is precise enough to provide information about the location of brain functions in patients who have brain tumors.
- Trial name
- NCT00724737
- Testing
- Presurgical MRI, functional MRI (fMRI) of the brain
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Chronic Kidney Disease
Whole Blood Platelet Aggregation in Chronic Kidney Disease Patients on Aspirin Study
Higher coronary in-stent thromboses and bleeding complications on anti-platelet agents are more common in Chronic Kidney Disease vs. non-Chronic Kidney Disease patients.
- Trial name
- WiCKDonASA (NCT01768637)
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Interpersonal Functioning, Psychological Distress
Assessing the Mechanism of Change of Functional Analytic Psychotherapy
This study seeks to assess the mechanisms of change of Functional Analytic Psychotherapy (FAP). FAP is a process-outcome psychotherapy that focuses on the therapeutic relationship, providing services to participants presenting…
- Trial name
- FAP (NCT03562962)
- Testing
- Functional Analytic Psychotherapy
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Cerebral Palsy, Chronic Pain
Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP.
- Trial name
- NCT05197946
- Testing
- MRI
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Low Back Pain
Evaluating Pain and Functional Outcomes of Active Release Technique Versus Strain-counter- Stain in Chronic Low Back Pain
clinical trial aims to compare the effects of Active Release Technique (ART) and Strain-Counter-Strain (SCS) on pain reduction and functional improvement in male patients aged 30-45 years with chronic low back pain (CLBP)…
- Trial name
- NCT07418346
- Testing
- Strain Counter Strain, Active Release Technique
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
COPD, Heart Failure, Congestive
Clinical Assessment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and/or Chronic Heart Failure (CHF)
Cigarette smoking, the major risk factor for COPD, causes not only airway and lung inflammation, but also systemic effects. These systemic effects of smoking could substantially contribute to the development of chronic diseases…
- Trial name
- NCT01114386
- Testing
- Lung function testing, echocardiography, blood sampling
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Chronic Kidney Disease
Safety and Pharmacokinetics of HRS-1780 in Healthy Subjects and Subjects With Impaired Renal Function
This is a multicenter, non-randomized, open-label, parallel-controlled study. The main objective is to evaluate the safety and pharmacokinetics of HRS-1780 in subjects with mild and moderate renal impairment versus healthy…
- Trial name
- NCT06039254
- Testing
- HRS-1780
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Bladder Disease, Bladder Retention Volume
ECHO-012 Kosmos Bladder Clinical Validation Study
The goal of this clinical trial is to compare the Kosmos Automatic Bladder Volume to the manual annotated bladder volume in participants across gender (male and female), age (children ages 7-17 and adults 18-89), and BMI strata…
- Conditions
- Bladder Disease, Bladder Retention Volume, Bladder Dysfunction, Bladder Function
- Trial name
- NCT06792851
- Testing
- Kosmos Bladder Volume Algorithm
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- EchoNous Inc.
Ketamine Treatment
Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI
Subanesthetic ketamine is currently used as a rapid-acting antidepressant. It is an antagonist of the N-methyl-d-aspartate (NMDA) receptor, but former results indicate that its action also depends on the noradrenaline system and…
- Trial name
- NCT05320120
- Testing
- 56mg esketamine (2x Spravato® 28 mg nasal spray), 0.9% saline solution nasal spray
- Where
- Austria
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Rupert Lanzenberger
Type 2 Diabetes, Coronary Heart Disease
Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)
The purpose of this study is to examine the existence of heart abnormalities in patients with diabetes and the effect of pioglitazone in correcting these abnormalities.
- Trial name
- NCT01588470
- Testing
- pioglitazone
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Healthy Volunteer
A Phase 1, Randomized, Double-blind, Placebo-controlled Crossover Study of RG7314 on the Potential Regulation of Higher Brain Functions in Healthy Male Participants: Proof of Mechanism
This is a single site, randomized, double-blind, three period cross-over, placebo-controlled, proof of mechanism study in healthy male subjects.
- Trial name
- NCT02205073
- Testing
- RG7314 RD + AVP SD
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Psychological Stress, Mental Fatigue
The Role of Physical Ardor in Triggering State Anattā and Psychophysiological Recovery
This study investigates how different types of aerobic exercise-specifically continuous treadmill running versus intermittent ball games-influence mental restoration in university students.
- Conditions
- Psychological Stress, Mental Fatigue, Self-Perception, Autonomic Nervous System Function
- Trial name
- SPAR (NCT07488169)
- Testing
- Continuous Aerobic Exercise (Treadmill-based), Intermittent Aerobic Exercise (Ball Games)
- Where
- China
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Lincoln University College