Clinical trials: GAD
Generalized Anxiety Disorder
A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)
The purpose of this study is to assess how safe ITI-1284 is and how well it can be tolerated in long-term, when given alone or with other medicines, in participants with generalized anxiety disorder (GAD) who have not responded…
- Trial name
- NCT07807865
- Testing
- ITI-1284
- Where
- 3 sites in United States
- Volunteers
- 900 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Depression, Generalized Anxiety Disorder
A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
For this trial, the investigators propose a prospective trial of a collaborative care program to identify and treat depression, generalized anxiety disorder, and panic disorder among patients admitted to the hospital for an acute…
- Conditions
- Depression, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- MOSAIC (NCT01201967)
- Testing
- Collaborative care, Usual care
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Massachusetts General Hospital
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Anxiety, Depression
Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)
This research study is aimed at understanding behaviors and brain circuits that relate to anxiety and depression. Our goal is to learn which circuits of the brain are involved in anxiety and how these circuits might affect daily…
- Trial name
- NCT02220309
- Testing
- Pramipexole Oral Tablet
- Where
- 3 sites in United States
- Volunteers
- 167 people
- Sponsor
- Stanford University
Major Depressive Disorder, Generalized Anxiety Disorder
Augmenting Mental Health Support Through a Supportive Text Messaging Program
Patients seeking mental health care and those being discharged from psychiatric units frequently express psychological distress.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Mental Health Wellness 1
- Trial name
- Text4Support (NCT05411302)
- Testing
- Mental health supportive text messages
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- Vincent Agyapong
Generalized Anxiety Disorder
Efficacy of Treatment for Generalized Anxiety Disorder
The purpose of these questionnaires is to give us an overview of how GAD has affected your life, and perhaps also to give us some clues about things that may have set you up to experience GAD.
- Trial name
- NCT00456742
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06563310
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Anxiety
Comorbidity Between Balance and Childhood Anxiety
Previous studies report frequent comorbidity of anxiety and sensory-motor imbalance in adults (Sklare et al., 2001). Only a few studies tested the comorbidity in children.
- Trial name
- NCT00599742
- Testing
- Balance training, Motor training
- Where
- 2 sites in Israel
- Volunteers
- 64 people
- Sponsor
- Lev-Hasharon Mental Healtlh Center
Depression, Generalized Anxiety
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic
Study description: The present study seeks to investigate the impact of various sources of information on psychopathology, and specifically health anxiety, depression, and general anxiety, during the COVID-19 pandemic.
- Conditions
- Depression, Generalized Anxiety, Health Anxiety
- Trial name
- NCT04442360
- Testing
- Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Generalized Anxiety Disorder
Treatment of Patients With Anxiety Disorder (0777-022)
The purpose of the study is to examine the safety and efficacy of MK0777 during treatment for Generalized Anxiety Disorder.
- Trial name
- NCT00539578
- Testing
- MK0777
- Volunteers
- 270 people
- Sponsor
- Merck Sharp & Dohme LLC
Procedural Anxiety, Procedural Pain
Oral Surgery Virtual Reality Glasses Study
The goal of this randomized trial is to investigate if using virtual reality (VR) glasses for patients who require non-emergent oral surgery procedures under intravenous (IV) sedation improves their overall experience compared to…
- Trial name
- NCT06723158
- Testing
- Virtual reality (VR) glasses with relaxation module
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston University
Generalized Anxiety Disorder
Efficacy of Adding Interpersonal and Emotional Processing Therapy Techniques to Cognitive Behavioral Therapy to Treat Generalized Anxiety Disorder
This study will test a version of cognitive behavioral therapy for generalized anxiety disorders that incorporates interpersonal and emotional processing techniques.
- Trial name
- NCT00951652
- Testing
- CBT, Interpersonal and emotional processing therapy, supportive listening
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Michelle G. Newman
Major Depressive Disorder, Generalized Anxiety Disorder
Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder
The primary objective is to test the hypothesis that quetiapine XR (Extended Release) monotherapy or adjunctive therapy to antidepressant is superior to placebo monotherapy or placebo adjunctive therapy to antidepressant(s) in…
- Trial name
- MDD/GAD (NCT00868374)
- Testing
- Quetiapine XR
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Keming Gao
Generalized Anxiety Disorder
Massage for GAD: Neuroimaging and Clinical Correlates of Response
This clinical trial will compare the effects of Swedish massage or light touch therapy on brain activity and symptoms of anxiety.
- Trial name
- NCT06506253
- Testing
- Swedish Massage Therapy, Light Touch Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Latent Autoimmune Diabetes in Adults
Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes
This study will evaluate the effects of 3 intra-nodal injections of GAD-alum (Diamyd), together with oral vitamin D supplementation.
- Trial name
- GADinLADA (NCT04262479)
- Testing
- recombinant human glutamic acid dehydrogenase (rhGAD65), formulated in aluminium hydrogel, Vitamin D
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 14 people
- Sponsor
- Norwegian University of Science and Technology
Healthy Volunteers, Generalized Anxiety Disorder (GAD)
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)
The purpose of this study is to assess the pharmacokinetics, safety, and tolerability following multiple ascending oral doses of ABBV-932 or placebo in healthy adult participants, participants with Generalized Anxiety Disorder…
- Conditions
- Healthy Volunteers, Generalized Anxiety Disorder (GAD), Bipolar Disorder (BPD)
- Trial name
- MAD (NCT06024239)
- Testing
- ABBV-932
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AbbVie
Social Anxiety Disorder, Separation Anxiety Disorder
Stepped Versus Stratified Care for Anxiety Disorders in Youth
The goal of this clinical trial is to compare stepped care to stratified care as overall healthcare models for children and adolescents aged 8-17 with anxiety disorders.
- Conditions
- Social Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Panic Disorder
- Trial name
- NCT06942429
- Testing
- Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 556 people
- Sponsor
- Region Skane
Generalized Anxiety Disorder
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety Disorder
The primary purpose of this study is to evaluate the efficacy of (SEROQUEL SR™ ) quetiapine fumarate sustained-release (SR) compared to placebo in the treatment of anxiety symptoms in patients with generalized anxiety disorder…
- Trial name
- SILVER (NCT00322595)
- Testing
- Quetiapine fumarate, Paroxetine
- Where
- 86 sites in Argentina, Bulgaria and 13 more
- Volunteers
- 800 people
- Sponsor
- AstraZeneca