Clinical trials: GAD
Bipolar Disorder, Anxiety
Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
The primary objective is to test the hypothesis that Quetiapine XR (Extended Release) monotherapy and adjunctive therapy is effective in the acute treatment of bipolar depression and comorbid generalized anxiety disorder in…
- Conditions
- Bipolar Disorder, Anxiety, Anxiety Disorders, Substance Use Disorders
- Trial name
- NCT00671853
- Testing
- Quetiapine XR
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University Hospitals Cleveland Medical Center
Anxiety, Anxiety Disorders
Anxiety, Inflammation, Stress, and Cannabinoids
This study investigates whether the anxiolytic effects and anti-inflammatory properties of cannabis vary as a function of the ratio of CBD to THC, with the goal that these effects may shed light on the mixed data linking cannabis…
- Conditions
- Anxiety, Anxiety Disorders, Anxiety Generalized, Anxiety Chronic
- Trial name
- NCT03491384
- Testing
- Cannabis (smoked flower, ingested edible)
- Where
- United States
- Volunteers
- 361 people
- Sponsor
- University of Colorado, Boulder
Social Anxiety Disorder, Generalized Anxiety Disorder
Visual Mismatch Negativity in Attention Bias Modifcation Treatment for Anxiety
this study examines the emergence of the visual mismatch negativity (vMMN) ERP component in response to deviations from the embedded contingency in attention bias modification treatment (ABMT) for social and generalized anxiety…
- Trial name
- NCT03016052
- Testing
- ABMT
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel Aviv University
Generalized Anxiety Disorder, Menopause
Black Cohosh as Alternative Therapy for Treating Menopause-Related Anxiety
This study will determine the effectiveness of the herb black cohosh for treating menopause-related anxiety symptoms in women. Study hypotheses: 1) Black cohosh will have a superior anti-anxiety effect compared to placebo.
- Trial name
- NCT00120458
- Testing
- Black cohosh
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Generalized Anxiety Disorder
Chamomile Therapy for Generalized Anxiety
This study will determine the effectiveness of chamomile extract for treating generalized anxiety disorder. Study hypotheses: 1)Chamomile extract will have a superior anti-anxiety effect compared to placebo.
- Trial name
- NCT00645983
- Testing
- Chamomile Extract
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Generalized Anxiety Disorder, Social Anxiety Disorder
Level of Physical Activity and Fear Learning
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05203731
- Testing
- Exercise, Sitting
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- NYU Langone Health
Generalized Anxiety, Stress Disorder, Posttraumatic
CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT
Adults with high anxiety sensitivity (AS) and a mental health diagnosis of anxiety, depression, or posttraumatic stress will be recruited and will be randomly assigned to either transdiagnostic cognitive behavioural therapy (CBT)…
- Conditions
- Generalized Anxiety, Stress Disorder, Posttraumatic, Social Anxiety, Major Depression
- Trial name
- NCT03015285
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Separation Anxiety Disorder, Social Phobia
Effectiveness of Cognitive Behavioral Therapy (CBT) for Child Anxiety Disorders in Community Clinics in Norway
The purpose of this study is to assess the effectiveness of a cognitive-behavioral intervention for children aged 7 to 12 years with anxiety disorders who are referred to ordinary community clinics.
- Conditions
- Separation Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00735995
- Testing
- Cognitive behavioral therapy (individual), Cognitive behavioral therapy (group)
- Where
- 3 sites in Norway
- Volunteers
- 165 people
- Sponsor
- Regionsenter for barn og unges psykiske helse
Anxiety Generalized, Breast Cancer Female
Anti-anxiety Biotics for Breast Cancer Survivors
Cancer survivors experience more rapid declines in health-related quality of life which include physical and psychological comorbidities, the latter of which may be subclinical and often overlooked by primary care providers.
- Trial name
- ABBCS (NCT04784182)
- Testing
- probiotic plus prebiotic supplement
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Auburn University
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix
Eating Disorders, Anorexia Nervosa
Targeting Social Function in Anxiety and Eating Disorders
Social processing and cognition are often altered in patients with eating disorders. The goal of this clinical trial is to assess two different social therapeutic interventions -- one educational, one interactive -- for their…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Atypical Anorexia Nervosa
- Trial name
- SF (NCT06198023)
- Testing
- Educational, Interactive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
General Anxiety Disorder
A Dose-Response Safety Study of ENX-102 in Patients With GAD
This is a randomized, double-blind, placebo-controlled study to evaluate the safety and tolerability of ENX-102 and determine a dose-response for the effects of ENX-102 in patients with GAD
- Trial name
- NCT06653296
- Testing
- ENX-102
- Where
- 3 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- Engrail Therapeutics INC
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcoholism, Generalized Anxiety Disorder
Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms.
- Conditions
- Alcoholism, Generalized Anxiety Disorder, Panic Disorder, Social Phobia
- Trial name
- NCT00141115
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York State Psychiatric Institute
Extranodal NK/T-cell Lymphoma, Nasal Type
GAD-M Regimen As First-Line Treatment in Untreated Extranodal NK/T Cell Lymphoma
The purpose of this study is to evaluate the efficacy and safety of High dose of Methotrexate combined with gemcitabine, pegaspargase and dexamethasone (GAD-M regimen) as first-line treatment in patients with de novo extranodal…
- Trial name
- NCT01991158
- Testing
- High dose of methotrexate, Gemcitabine, Pegaspargase
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Anxiety Disorders
Transdiagnostic Treatment for Anxiety Disorders in Two Cities of México
This study evaluates the effectiveness of The Unified Transdiagnostic Protocol, a psychological treatment for the intervention of a broad range of anxiety disorders.
- Trial name
- NCT03916315
- Testing
- Transdiagnostic Treatment
- Where
- 2 sites in Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Generalized Anxiety Disorder
rTMS Treatment in Patients With General Anxiety Disorder
This study will compare the change detected by a standardized rating scale (Hamilton Anxiety Rating Scale) scores in the active treatment group as compared to sham (placebo) group after 6 weeks of rTMS treatments.
- Trial name
- NCT00616447
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 2 sites in Bulgaria, Canada
- Volunteers
- 30 people
- Sponsor
- Queen's University
Generalized Anxiety Disorder
Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder
A placebo-controlled superiority design was used to evaluate the efficacy of 40 mg/ day of Crisugabalin capsules in the treatment of GAD.
- Trial name
- CEASE-GAD (NCT07330648)
- Testing
- Crisugabalin 20mg bid, Venlafaxine-XR 75mg bid, Crisugabalin capsules mimic 0mg/capsule bid
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Anhui Medical University
Specific Phobia, Separation Anxiety
Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical Setting
An open trial will be conducted at the Child and Mental Health Service (CAMHS) unit in the rural county Jämtland in Sweden to test the feasibility and efficacy of Internet-delivered Cognitive Behavior Therapy (ICBT) for children…
- Conditions
- Specific Phobia, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT02306356
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Generalized Anxiety Disorder
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, phase 3, randomized, double-blind, parallel-group, 2-arm, placebo controlled, multicenter trial designed to compare the efficacy, safety and tolerability of a fixed dose of SEP-363856 (75 millligrams per day…
- Trial name
- NCT07767903
- Testing
- SEP-363856
- Where
- 11 sites in United States
- Volunteers
- 384 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.