Clinical trials: GAD
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Generalized Anxiety Disorder, Separation Anxiety Disorder
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep
1 out of 8 children, adolescents, and young adults suffer from an anxiety disorder. Studies over the past decade show that selective serotonin-reuptake inhibitors (SSRIs), a class of medication that treats anxiety in adults, also…
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT02189213
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Generalized Anxiety Disorder
Anxiety Symptoms in Relation to Use of Hemp-derived, Full Spectrum Cannabidiol (CBD)
Generalized anxiety disorder affects about 6.8 million adults in the United States, therefore its treatment is of major public health interest.
- Trial name
- NCT05023759
- Testing
- Formula30A Full Spectrum Hemp Cannabidiol 25mg Capsules
- Where
- 6 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- Formula30A LLC
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood
Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders
This study aims to investigate whether a parent-based treatment for childhood anxiety disorders engages child brain circuitry implicated in children's reliance on parents to reduce anxiety (R61), and whether change in child brain…
- Conditions
- Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder
- Trial name
- NCT03585010
- Testing
- Supportive Parenting for Anxious Childhood Emotions, Parent Educational Support, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Yale University
Anxiety Disorders
Duloxetine Compared With Placebo in Patients With Generalized Anxiety Disorder
This is a clinical trial assessing duloxetine compared with placebo in patients who have generalized anxiety disorder.
- Trial name
- NCT00122824
- Testing
- duloxetine hydrochloride
- Where
- 7 sites in United States, Finland and 5 more
- Volunteers
- 480 people
- Sponsor
- Eli Lilly and Company
Parkinson's Disease
Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's Disease
The objective of this study is to evaluate the long-term safety of AAV-GAD delivered bilaterally to the subthalamic nuclei (STN) in participants with Parkinson's disease.
- Trial name
- NCT05894343
- Testing
- AAV-GAD
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- MeiraGTx, LLC
Anxiety, Anxiety Generalized
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia
Caregivers of adults with dementia report higher distress, including anxiety and depressive symptoms, burden, and existential suffering, than caregivers of people with other chronic diseases.
- Conditions
- Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
- Trial name
- TACTICs (NCT04338750)
- Testing
- Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Anxiety Disorders
An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Patients With Generalized Anxiety Disorder
The purpose of the study is to evaluate the efficacy and safety of SR58611A in patients with Generalized Anxiety Disorder. The primary objective is to evaluate the efficacy of a 700 mg dose of SR58611A compared to placebo in…
- Trial name
- AQUARIUS (NCT00266747)
- Testing
- SR58611A
- Where
- 7 sites in Argentina, Austria and 5 more
- Volunteers
- 366 people
- Sponsor
- Sanofi
GAD 65 Antibody-associated Epilepsy
Diazepam Trial in GAD65 Associated Epilepsy
The purpose of this study is to determine whether diazepam reduces the frequency of seizures in GAD65 antibody associated epilepsy.
- Trial name
- NCT05361447
- Testing
- Diazepam
- Where
- United States
- Sponsor
- Mayo Clinic
Worry, Anxiety
Effects of Duloxetine on Pathological Worry in Patients With Generalized Anxiety Disorder: A fMRI Study
(1) to compare the differences of neural activation of pathological worry between pre-treatment GAD patients and normal subjects; (2) to measure the differences of brain activation on worry in GAD patients before and after…
- Trial name
- NCT00491348
- Testing
- duloxetine hydrochloride
- Where
- Taiwan
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Panic Disorder, Agoraphobia
Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders
Anxiety disorders are the most common mental disorders in community settings, and they are associated with significant psychological distress, functional and social impairment.
- Conditions
- Panic Disorder, Agoraphobia, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- T-CBT (NCT02811458)
- Testing
- Transdiagnostic Cognitive-Behavioral Therapy
- Where
- 3 sites in Canada
- Volunteers
- 231 people
- Sponsor
- Université de Sherbrooke
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Generalized Anxiety Disorder, Social Anxiety Disorder
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03925987
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Generalized Anxiety Disorder
An Open-label Study to Investigate the Absorption, Metabolism and Excretion of Radiolabeled PD 0332334 in Six Healthy Male Volunteers
The purpose of this study is to investigate the absorption, metabolism and excretion of [14C] PD 0332334 to characterize plasma, fecal and urinary radioactivity and identify any metabolites of [14C] PD 0332334.
- Trial name
- NCT00537615
- Testing
- PD 0332334
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Epilepsy, Anxiety Disorders and Symptoms
Pilot to Evaluate VR-Therapy on People With Epilepsy and Related Anxiety
Over 28% of people with epilepsy (PwE) struggle from at least one anxiety disorder, making anxiety the most common psychiatric comorbidity in this population.
- Trial name
- AnxEpiVR (NCT05296057)
- Testing
- Participants Receiving VR-Exposure Therapy Treatment
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Generalized Anxiety Disorder
Physical Exercise Augmented CBT for GAD
Generalised anxiety disorder (GAD) is a severe and debilitating anxiety disorder that is highly prevalent among older adults. Anxiety and GAD is a well-documented risk factor for the development of other severe conditions such as…
- Trial name
- PEXACOG (NCT02690441)
- Testing
- Cognitive Behavioural Therapy, Physical Exercise
- Where
- Norway
- Volunteers
- 53 people
- Sponsor
- Solli Distriktspsykiatriske Senter
Generalized Anxiety Disorder
Comparing the Efficacy of Two Neurofeedback Protocols for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is one of the most prevalent mental disorders in adults, marked by excessive and uncontrollable worry about various events or activities.
- Trial name
- NCT06361953
- Testing
- EEG Neurofeedback
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Generalized Anxiety Disorder
Treatment of Patients With Anxiety Disorder (0777-022)
The purpose of the study is to examine the safety and efficacy of MK0777 during treatment for Generalized Anxiety Disorder.
- Trial name
- NCT00539578
- Testing
- MK0777
- Volunteers
- 270 people
- Sponsor
- Merck Sharp & Dohme LLC