Clinical trials: GAD
Depression, Anxiety
Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients
This is a prospective, randomized clinical trial to investigate the clinical impact of a preemptive pharmacogenomics strategy to guide antidepressant therapy in cancer patients.
- Conditions
- Depression, Anxiety, Generalized Anxiety Disorder, Depressive Disorder
- Trial name
- NCT03674138
- Testing
- DNA-guided choice of therapy, Clinical management
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
Anxiety Disorders Generalized
A Pilot fMRI Study of TMS in Late-Life Severe Worry
Investigators will test a novel intervention through experimental therapeutic approach using fMRI-directed Intermittent Theta Burst Stimulation (iTBS), a high frequency TMS paradigm, for the treatment of severe, uncontrollable…
- Trial name
- TINA (NCT03577106)
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Carmen Andreescu
Generalized Anxiety Disorder
Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response
This project aims to identify brain and behavioral characteristics of individuals experiencing symptoms of generalized anxiety disorder that will predict the effectiveness of Exposure-based therapy versus Behavioral Activation…
- Trial name
- NCT02807480
- Testing
- Exposure-based therapy, Behavioral Activation therapy, Computer-based behavioral assessment
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Major Depressive Disorder, Depression
Cognitive Training for Mood and Anxiety Disorders
The purpose of this study is to investigate the effects of a computerized cognitive training program (an attention and memory exercise performed on a computer) on thinking and memory in individuals with mood and anxiety…
- Conditions
- Major Depressive Disorder, Depression, Bipolar Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02256566
- Testing
- emotional memory training exercise, memory training exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia
INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1
The focus of this study is not about what it is like to have a mental disorder, but instead the diagnostic experience. Some people find diagnoses helpful, but some find them upsetting and harmful.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia, Generalised Anxiety Disorder, Bipolar Disorder
- Trial name
- INCLUDE (NCT03131505)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Anxiety Disorders, Generalized Anxiety Disorder
Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety Disorder
The current study examines whether change-readiness, and consequently treatment outcome, can be enhanced in Cognitive Behavioral Therapy (CBT) for severe Generalized Anxiety Disorder (GAD) by adding a brief course of Motivational…
- Trial name
- NCT01488799
- Testing
- Motivational Interviewing and Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 85 people
- Sponsor
- York University
Generalized Anxiety Disorder
Effects and Mechanisms of Change of Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
The goal of this clinical trial is to compare two psychological treatments for Generalized Anxiety Disorder. The main questions it aims to answer are: How well do these treatments work compared to earlier studies? Is one of the…
- Trial name
- ORIGAMI (NCT05849493)
- Testing
- Metacognitive Internet delivered Cognitive Behavior Therapy, Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Depression - Major Depressive Disorder, Generalised Anxiety Disorder
Effectiveness of Internet-based Unified Protocol (iUP) for Emotional Problems: A Randomized Controlled Trial
The goal of this clinical trial is to learn if an internet-based Unified Protocol (iUP) intervention is effective for treating depression and anxiety disorders in Hong Kong young adults aged 18-29 years.
- Conditions
- Depression - Major Depressive Disorder, Generalised Anxiety Disorder, Anxiety Disorder (Panic Disorder or GAD), Depressive and Anxiety Disorders
- Trial name
- NCT07908628
- Testing
- Internet-based Unified Protocol (iUP), Waitlist Control Group
- Where
- Hong Kong
- Volunteers
- 78 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Generalized Anxiety, Anger
Experiences of Anger in Patients in Primary Health Care With Symptoms of Generalized Anxiety
Symptoms of generalized anxiety is common in the general population and is often treated in primary health care. Anger is an emotion that can lead to interpersonal problems but can also be an agent for justice and change.
- Conditions
- Generalized Anxiety, Anger, Primary Health Care
- Trial name
- NCT04702711
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Kronoberg County Council
Anxiety, Generalized Anxiety Disorder
Comparing the Efficacy of E-CBT to Mental Health Coaching for GAD
This study will compare the efficacy of an electronically-delivered cognitive behavioural therapy (e-CBT) program versus a mental health coaching program to treat generalized anxiety disorder (GAD).
- Trial name
- NCT04754438
- Testing
- e-CBT, Mental Health Coaching
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- Dr. Nazanin Alavi
Generalized Anxiety Disorder
Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study
This is a feasibility study for trigeminal nerve stimulation (TNS) in patients with treatment-resistant generalized anxiety disorder (TR-GAD).
- Trial name
- NCT06278909
- Testing
- Trigeminal Nerve Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Dr. Rafael Freire
Anxiety, Generalized Anxiety Disorder
Brain Stimulation & Generalized Anxiety Study
Examine the safety and effectiveness of the Fisher Wallace Cranial Electrotherapy Stimulator (CES) Device on Generalized Anxiety Disorder using two (2) 20-minute per day treatment sessions over eight weeks.
- Conditions
- Anxiety, Generalized Anxiety Disorder, Generalized Anxiety
- Trial name
- NCT04751864
- Testing
- Cranial Electrotherapy Stimulator (CES) Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ProofPilot
General Anxiety Disorder
Evaluate the Beneficial Effects of an Oral Nutritional Supplement Based on Leonurus Cardiaca for the Improvement of Mood and Anxiety
This study aims to evaluate the efficacy and safety of Leonurus cardiaca extract in reducing anxiety symptoms in adults with Generalized Anxiety Disorder (GAD).
- Trial name
- LEONORUS (NCT06954038)
- Testing
- Leonurus cardiaca extract 250 mg, Leonurus cardiaca extract 500 mg
- Volunteers
- 60 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Generalized Anxiety Disorder
Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions
Generalized anxiety disorder (GAD) is an extremely prevalent and debilitating mental health disorder. Currently, the gold standard treatment for GAD is cognitive behavioural therapy (CBT) and/or pharmacotherapy.
- Trial name
- NCT04478526
- Testing
- SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/ Serotonin and Norepinephrine Reuptake Inhibitors), Electronic Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- Dr. Nazanin Alavi
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus…
- Conditions
- Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT05467683
- Testing
- Exposure-Based Therapy
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jasper A. Smits
Patients With Major Depressive Disorder
Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life…
- Trial name
- NCT07300527
- Testing
- Cognitive Behavior Therapy, treatment as usual (TAU) (Control Group)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Anxiety Disorder (Panic Disorder or GAD), Well Being
Religiously Integrated Cognitive Behavioral Therapy
This study aims to examine the effect of a newly developed religously oriented cognitive behavioral group therapy program on the level of anxiety and well-being in young adults compared to the traditional cognitive behavioral…
- Trial name
- NCT07334769
- Testing
- Religiosly Integrated Cognitive Behavioral GroupTherapy, Traditional Cognitive Behavioral Group Therapy, Waiting Group
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Generalized Anxiety Disorder
CannaRiver CBD Calm for Anxiety, Sleep, and Well-Being in Adults With Generalized Anxiety Disorder
This open-label, single-group, non-randomized interventional study will evaluate longitudinal changes in anxiety symptoms, sleep quality, psychological well-being, treatment adherence, tolerability, and safety in adults with…
- Trial name
- CR-GAD-60 (NCT07821840)
- Testing
- Cannabidiol (CBD) With Cannabinol (CBN) and Cannabigerol (CBG) Oral Tincture (CannaRiver CBD Calm)
- Volunteers
- 60 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Anorexia, Generalized Anxiety
Overgeneralization of Conditioned Fear as a Pathogenic Marker of Anorexia Nervosa
Anorexia nervosa is a chronic mental health condition characterized by maladaptive food consumption (i.e., hypophagia) and distorted body image.
- Trial name
- NCT02148042
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Minnesota