Clinical trials: GAD
Generalized Anxiety Disorder
A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
This is a single dose study to investigate the efficacy, safety, tolerability and the PK, of SYT-510 in participants who meet diagnostic criteria of GAD.
- Trial name
- NCT07478744
- Testing
- SYT-510
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Synendos Therapeutics AG
Generalised Anxiety Disorder
Self-help Lifestyle Medicine for Generalized Anxiety Symptoms
This study will examine the effects of smartphone-based lifestyle medicine for alleviating generalised anxiety symptoms in Chinese population.
- Trial name
- NCT05278455
- Testing
- Lifestyle Medicine
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Panic Disorder, Generalized Anxiety Disorder
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project.
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- Trial name
- NCT03113175
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Amager Hospital
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06563310
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Generalized Anxiety Disorder, Emotional Disorder
Acceptability/Feasibility of IU Intervention
Anxiety disorders are prominent mental health burdens, affecting roughly 1 in 5 adults annually, and a third of individuals over the course of their life.
- Trial name
- CLUE (NCT05172427)
- Testing
- 14 days of EMI, Uncertainty reappraisal training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ohio University
Generalized Anxiety Disorder (GAD)
Acupuncture for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a common mental disorder characterized by persistent excessive worry, which seriously affects patients' quality of life.
- Trial name
- NCT07798986
- Testing
- 2Hz electro-acupuncture, 100Hz electro-acupuncture, 2Hz/100Hz electro-acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Generalized Anxiety Disorder
Internet-based Treatment of Generalized Anxiety Disorder
The purpose of this study is to determine whether internet-administered cognitive behavior therapy is a feasible treatment for generalized anxiety disorder.
- Trial name
- NCT01570374
- Testing
- Internet-based cognitive behavioral therapy (iCBT)
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Umeå University
Generalized Anxiety Disorder
Long Term Chamomile Therapy for Anxiety
Prior research has shown that chamomile may be an effective, short-term anti-anxiety treatment. This study will examine the initial and long-term benefits of chamomile extract therapy for the prevention of recurrent anxiety…
- Trial name
- NCT01072344
- Testing
- Chamomile (Matricaria recutita)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Pennsylvania
Generalized Anxiety Disorder
RCT of an Acceptance-based Behavior Therapy for GAD
The purpose of this study is to determine whether acceptance-based behavior therapy for GAD results in greater symptom reduction and increased quality of life than applied relaxation.
- Trial name
- NCT00961493
- Testing
- Acceptance based behavioral therapy, Applied relaxation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Massachusetts, Boston
Generalized Anxiety Disorder
Dietary Counselling Plus Omega-3 Supplementation in the Treatment of Generalized Anxiety Disorder
This study will assess the feasibility and acceptability of a combination intervention including dietary counselling and omega-3 fatty acid supplementation among women with generalized anxiety disorder.
- Trial name
- EASe-GAD (NCT05573672)
- Testing
- Dietary Counselling combined with Omega-3 Supplementation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Anxiety, Depression
Remember Stuff: A Dyadic-focused Technology to Support Persons With Alzheimer's Disease in the Community
Test the usability, perceptions and acceptability of a computer monitor for participant diagnosed with ADRD and their caregiver who will program the applications specifically for each individual to help them remember activities…
- Conditions
- Anxiety, Depression, Caregiver Burnout, Anxiety Generalized
- Trial name
- R/S (NCT04626804)
- Testing
- Remember Stuff: A Dyadic-focused Technology to Support Persons with Alzheimer's Disease in the Community
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic iCBT for Depression and Anxiety
This 8-week, pilot randomized, controlled trial to evaluate the benefits of transdiagnostic Internet-based CBT (iCBT) in young adults with MDD, SAD, PD or GAD.
- Conditions
- Major Depressive Disorder, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT02266693
- Testing
- iCBT
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- Centre for Addiction and Mental Health
Recurrent Pregnancy Loss(RPL), Anxiety
High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety
The goal of this clinical trial is to determine whether high-intensity, low-frequency periodic repetitive transcranial magnetic stimulation (rTMS) applied to the right dorsolateral prefrontal cortex (DLPFC) can modulate cardiac…
- Trial name
- NCT07233278
- Testing
- Rhythmic repetitive transcranial magnetic stimulation (rTMS) at 120% RMT, 1 Hz, 60-s cycles
- Where
- 3 sites in China
- Volunteers
- 48 people
- Sponsor
- Shenyang Medical College
Generalized Anxiety Disorder
Treating Young Adult Generalized Anxiety Disorder With Text-Message Delivered Cognitive Behavioral Therapy
The purpose of the proposed study is to test the feasibility and efficacy of a "anxiety-focused" text-delivered counseling program to reduce anxiety symptoms among young adults (18-25) with elevated anxiety symptoms.
- Trial name
- NCT06774573
- Testing
- CBT-txt-A
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Anxiety Disorder
GEM 1.5 mg b.i.d. to 4.5 mg b.i.d. Versus Lorazepam in GAD (0777-026)
This study will determine the effectiveness of MK0777 GEM versus Lorazepam in the treatment of patients with generalized anxiety disorder.
- Trial name
- NCT00546624
- Testing
- MK0777
- Volunteers
- 38 people
- Sponsor
- Merck Sharp & Dohme LLC
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Generalized Anxiety Disorder
Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a serious and long-lasting condition that can greatly reduce quality of life, work functioning, and use of health services.
- Trial name
- NCT07579897
- Testing
- Individual Metacognitive Therapy, Group Metacognitive Therapy
- Where
- 2 sites in Norway
- Volunteers
- 64 people
- Sponsor
- Sorlandet Hospital HF
Anxiety Disorders Generalized, Depression
Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners
This pilot study engaged pregnant couples experiencing elevated symptoms of maternal anxiety or depression with an existing online psychoeducation intervention, the Online Mothers and Babies Course (eMB).
- Trial name
- NCT05867680
- Testing
- Online Mothers and Babies Course (eMB)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Missouri-Columbia
Generalized Anxiety Disorder, Social Anxiety Disorder
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 75 participants with clinical anxiety and…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03899090
- Testing
- Float pool, Float chair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anxiety Disorders
Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults With Generalized Anxiety Disorder.
A 12-Month, Open-Label, Flexible-Dosage Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults with Generalized Anxiety Disorder.
- Trial name
- NCT00214994
- Testing
- Gabitril
- Where
- 93 sites in United States, Canada
- Sponsor
- Cephalon