Clinical trials: GDM
Diabetes Mellitus, Type 2, Gestational Diabetes
Prevention of Type 2 Diabetes and Gestational Diabetes Among Women in Kisantu, Democratic Republic of Congo
This study aims to develop and implement a long-term program focused on the prevention of type 2 diabetes Mellitus (T2DM) and gestational diabetes mellitus (GDM) in women of reproductive age through lifestyle modification.
- Trial name
- KIS-Antwerp (NCT05039307)
- Testing
- Educational and motivational strategy
- Where
- 6 sites in Democratic Republic of the Congo
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Healthy, Gestational Diabetes Mellitus
Elucidation of Breast Milk Composition and Structure Over the First Year of Lactation: UC Davis Lactation Study
This observational study is designed to determine how sugars, lipids and proteins in breast milk vary among mothers; is affected by maternal diet, health and microbiota and vary over the course of lactation.
- Conditions
- Healthy, Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
- Trial name
- NCT01817127
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pre-eclampsia, Gestational Diabetes Mellitus (GDM)
Placental Biology in Health and Disease
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR).
- Conditions
- Pre-eclampsia, Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), Pregnancy Induced Hypertension (PIH)
- Trial name
- NCT07470320
- Testing
- There are no interventions for this study
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled
Pregnancy Complications in Women With BMI>25 kg/m2 Enrolled in a Healthy Lifestyle and Eating Habits Program
The investigators evaluate if changing eating habits and introducing a correct lifestyle in women with BMI >25 Kg/m2 would improve unfavorable maternal-fetal outcomes associated with excessive weight gain (EWG) during pregnancy.
- Conditions
- Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled, Exercise Addiction, High-Risk Pregnancy
- Trial name
- TLC (NCT01783210)
- Testing
- Specific Therapeutic Lifestyle Changes program in pregnancy, Dietary and behavioral counselling in pregnancy
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Neonatal Hypoglycemia, Gestational Diabetes
Accuracy of Interstitial Continuous Glucose Sensors in Neonates
Low blood sugar in newborns is common and if prolonged or untreated may place them at increased risk for later learning and behavior challenges.
- Conditions
- Neonatal Hypoglycemia, Gestational Diabetes, Maternal Obesity Complicating Pregnancy, Small-for-gestational Age
- Trial name
- NCT07133906
- Testing
- Continuous glucose monitoring, Cerebral near-infrared spectroscopy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Prediabetic State, Obesity
Presessions for the National Diabetes Prevention Program
The National Diabetes Prevention Program (NDPP) is a widely available, evidence-based intervention that promotes weight loss to prevent type 2 diabetes; however, participant attendance is problematic and leads to suboptimal…
- Conditions
- Prediabetic State, Obesity, Gestational Diabetes
- Trial name
- NCT04022499
- Testing
- Presessions, National Diabetes Prevention Program
- Where
- United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Polycystic Ovary Syndrome
Effects of Oral Inositol Supplementation on Obstetrics Outcomes in PCOS Women
Polycystic ovarian syndrome (PCOS) is a heterogeneous, multifaceted and complex disorder characterized by insulin resistance (IR), hyperinsulinemia, and hyperandrogenism leading ovarian disfunction and infertility.
- Trial name
- IPOSI-1 (NCT03585738)
- Testing
- Inositol + Folic acid, Folic acid
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Diabetes, Gestational Diabetes
Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes
This trial is conducted in the United States of America (USA). The purpose of this study is to test whether NovoLog (insulin aspart) is a safe and at least as effective alternative to regular human insulin for the control of…
- Trial name
- NCT00065130
- Testing
- human insulin, insulin NPH, insulin aspart
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Gestational Diabetes, Pregestational Diabetes
Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes
Pregestational diabetes (PGD) during pregnancy may be associated with an increased rate of spontaneous abortions, intrauterine death and congenital anomalies among the offspring.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, IDM (Infant of Diabetic Mothers), Neurodevelopmental Outcome
- Trial name
- NCT01255384
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Gestational Diabetes, Obesity
Healthy Diet for Healthy Moms and Babies
The purpose of this clinical study is to collect baseline information on dietary habits and metabolic risk factors, and to examine the effects of a dietary intervention focusing on fiber and antioxidant rich berries on the…
- Conditions
- Gestational Diabetes, Obesity, Pregnancy, High Risk
- Trial name
- NCT03467503
- Testing
- Blueberry + soluble fiber
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Aerobic and Resistance Exercise
Application of Aerobic and Resistance Exercise in Blood Glucose Control in Pregnant Women With GDM
Objective:The aim of this study was to explore the rationality and clinical value of aerobic exercise during pregnancy in blood glucose control of pregnant women with GDM, and to provide theoretical basis for more appropriate…
- Trial name
- NCT05901402
- Testing
- aerobic and resistance exercise
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gestational Diabetes Mellitus
Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus
Metformin vs Control to prevent gestational diabetes mellitus (GDM) in women with a high risk for GDM, an open label randomized controlled trial' The Medico-GDM trial
- Trial name
- Medico-GDM (NCT02275845)
- Testing
- Metformin, control diet
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Maasstad Hospital
Weight Loss, Gestational Diabetes
Pragmatic Lifestyle Pregnancy and Post Pregnancy Intervention for Overweight Women With Gestational Diabetes Mellitus
This study is designed to determine if a postnatal lifestyle intervention will lead to weight reduction over a 12 month period post-delivery in women who have been diagnosed with gestational diabetes mellitus and who have a BMI…
- Trial name
- PAIGE2 (NCT04579016)
- Testing
- PAIGE2 lifestyle intervention, Standard care
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Gestational Diabetes Mellitus
Preventing Recurrent Gestational Diabetes With Metformin
Study Hypothesis: Intervention with metformin therapy early in pregnancy will prevent gestational diabetes mellitus recurring in previously affected pregnancies.
- Trial name
- PRoDroME (NCT02394158)
- Testing
- Metformin
- Where
- 2 sites in United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diabetes, Gestational, Insulin Resistance
Metformin in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a condition that manifests as high blood sugar levels (hyperglycemia) during pregnancy in previously healthy women.
- Trial name
- MetGDM (NCT00681460)
- Testing
- human recombined insulin, metformin
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- K. Marcinkowski University of Medical Sciences
Pregnancy in Diabetes, Pregnancy
Are There Any Clinical Benefits to Screening for Late -Onset Gestational Diabetes Mellitus?"
This study aims to screen women who have a negative Gestational diabetes mellitus (GDM) result in routine screening tests or who have never had it with the Fasting Blood Glucose Test (FBG) at 32-34 weeks of gestation to diagnose…
- Conditions
- Pregnancy in Diabetes, Pregnancy, Pregnancy Outcomes
- Trial name
- NCT07776314
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Gestational Diabetes
EARLY Pregnancy GLucose prOfiles in Women With and Without GDM Risk Factors: EARLY-GLOW
Background: Gestational diabetes mellitus (GDM) is associated with increased maternal and neonatal complications, including macrosomia, preeclampsia, and long-term metabolic consequences for both mother and child.
- Trial name
- EARLY-GLOW (NCT07783178)
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- DCB Research AG
Pregnancy, Obesity
Nutrition and Pregnancy Intervention Study
A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6…
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus, Adiposity
- Trial name
- NCT01922791
- Where
- 2 sites in Finland
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Gestational Diabetes Mellitus
Association Between Dietary Habits and Gestational Diabetes
Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of varying severity with onset or first recognition during pregnancy.
- Trial name
- NCT03287297
- Testing
- OGTT & HBA1c
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University