Clinical trials: GDM
Diabetes, Gestational
The Effect of a Low Glycemic Index Diet on Blood Sugar Control in Pregnant Women at Risk for Gestational Diabetes
Gestational diabetes mellitus (GDM) is a condition in which high blood sugar levels occur during pregnancy. GDM increases the risk of medical complications during pregnancy which may harm the mother and her baby.
- Trial name
- NCT01105455
- Testing
- Nutrition education
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes, Overweight and Obesity
Educational Intervention in the First 18 Months of Life to Prevent/Manage Obesity of Children After Gestational Diabetes
In order to evaluate the effect of an educational intervention on mothers with gestational diabetes and their offspring in the first 18 months of life, The intervention will be applied to mothers with gestational diabetes, and a…
- Trial name
- NCT04493177
- Testing
- Educational intervention, Conventional treatment Guia de Practica Clinica IMSS-029-08
- Where
- Mexico
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Gestational Diabetes, Glucose Metabolism Disorders
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)
This study aims to test the following hypotheses in a randomized controlled trial of post-partum women with a history of gestational diabetes mellitus (GDM) that will be followed up for up to 4 years: 1.
- Conditions
- Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- I-HIPS (NCT05081037)
- Testing
- Wearable Care Group
- Where
- Singapore
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes Mellitus in Pregnancy, Pregnancy in Diabetic
Effect of Diaphragmatic Breathing Exercise on Fatigue and Quality of Life in Pregnant Women With Gestational Diabetes
Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy. GDM, which is in the high-risk pregnancy category, causes fatigue during pregnancy due to both hormonal changes and pregnancy…
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Pregnancy in Diabetic, Fatigue, Quality of Life
- Trial name
- NCT06265935
- Testing
- Experimental Group
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Gestational Diabetes Mellitus (GDM), Blood Glucose
Diabetes, Insulin, Gut, Enteric Supplementation Trial
Pregnancy is a critical window for metabolic health, and early changes in blood sugar regulation can increase the risk of gestational diabetes mellitus (GDM), which affects both maternal and infant health.
- Conditions
- Gestational Diabetes Mellitus (GDM), Blood Glucose, Insulin Resistance, Diabetes, Gut Microbiome
- Trial name
- DIGEST (NCT07682077)
- Testing
- Kefir
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Glucose Intolerance During Pregnancy, Body Composition
- Trial name
- eMOM (NCT03681054)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Overweight and Obesity, Insulin Resistance
DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)
Women with excess adiposity while pregnant are more likely to develop gestational diabetes and high blood pressure during pregnancy than women of healthy weights.
- Conditions
- Overweight and Obesity, Insulin Resistance, Diabetes, Gestational, Hypertension in Pregnancy
- Trial name
- NCT00865683
- Testing
- DHA Supplements
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Gestational Diabetes Mellitus
Insulin Action During Pregnancy in Woman at High Risk for Gestational Diabetes
The project objective is to validate a new indirect estimate of insulin status in both pregnant African-American women and Caucasian women in southern Louisiana who are at risk for gestational diabetes mellitus.
- Trial name
- DRM (NCT00687479)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Woman's
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity, Diabetes, Gestational
Metabolism, Breastmilk, and Microbiome
The objective of this pilot study is to compare breast milk composition in mothers of three different metabolic states (normal weight, obese, and gestational diabetic) and to determine the extent to which breastmilk components…
- Trial name
- NCT03522597
- Where
- United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Fetal Cardiac Anomaly, Gestational Diabetes
Fetal Cardiac Remodeling in Gestational Diabetic Pregnancies at the Moment of Diagnosis
The aim of the present study will be to evaluate whether fetal cardiac remodeling is already present at the moment of the diagnosis of gestational diabetes (GD) in comparison with fetuses of healthy pregnant women.
- Trial name
- NCT05260931
- Testing
- Fetal echocardiography
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Diabetes Mellitus in Pregnancy, Diabetes, Gestational
Glycemic Targets for Pregnant Women With GDM and T2DM
The purpose of this randomized clinical trial is to determine whether glycemic targets that are lower than those currently recommended by the American Diabetes Association (ADA) and the American College of Obstetricians and…
- Conditions
- Diabetes Mellitus in Pregnancy, Diabetes, Gestational, Diabetes Mellitus, Type 2
- Trial name
- NCT04672031
- Testing
- Glycemic Targets
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gestational Diabetes
Trimester Sequential Estimation of Serum Zonulin as a Predictor of Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is the development of glucose intolerance (GI) during pregnancy in a previously normoglycemic (NG) woman and associated with insulin resistance (IR).
- Trial name
- NCT06336512
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benha University
Gestational Diabetes, Oxidative Stress
Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.
- Conditions
- Gestational Diabetes, Oxidative Stress, Vascular Endothelial Function
- Trial name
- NCT05946798
- Testing
- Acetylcholine, Insulin aspart
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Gestational Diabetes Mellitus
The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes
It is well-known that women with previous gestational diabetes mellitus are in risk of developing type 2 diabetes later in life; approximately half of the women develop overt type 2 diabetes within the first 10 years after…
- Trial name
- NCT01795248
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tina Vilsboll
Gestational Diabetes Mellitus
Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)
This is a pharmacokinetic and pharmacodynamic study evaluating glyburide, metformin, and combination treatment for gestational diabetes mellitus.
- Trial name
- GDM (NCT01329016)
- Testing
- Glyburide, Metformin, Glyburide-Metformin combination
- Where
- 4 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Type 2 Diabetes, Gestational Diabetes
Exploring Nutritype Signature of Type 2 Diabetes Risks in Women Post-Gestational Diabetes Mellitus
Women post-gestational diabetes mellitus (GDM) have more than 7-fold increased risk of having future type 2 diabetes mellitus (T2DM).
- Trial name
- NCT04190199
- Testing
- Observational
- Where
- Malaysia
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Gestational Diabetes
Carbohydrate Restriction in Pregnant Women With Gestation Diabetes Mellitus
The purpose of this controlled, randomized intervention is to investigate whether a carbohydrate-restricted diet, having a positive effect on blood sugar and weigh maintaining in diabetes, is effective and safe for pregnant woman…
- Trial name
- NCT04051359
- Testing
- Low carbohydrate (130 g) diet
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
A diagnosis of gestational diabetes mellitus (GDM)has significant implications for the future health of the mother. GDM is often the culmination of years of unrecognized and unmodified diabetes risk factors that lead to overt and…
- Conditions
- Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT01234649
- Testing
- Metformin XR plus liraglutide
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Woman's