Clinical trials: GDM
Gestational Diabetes
Daily Versus Every Other Day Glucose Monitoring in Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) occurs secondary to carbohydrate intolerance in pregnancy. Screening of GDM occurs between 24 to 28 weeks gestation by a screening 1-hour 50g glucose challenge test and confirmed with a 100g…
- Trial name
- NCT04857073
- Testing
- Glucose Monitoring
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gestational Diabetes Mellitus, Preeclampsia
Leptin and Cytokines in Diabetic Pregnancy - Physiologic or Pathogenic Role
Leptin, a circulating hormone expressed abundantly in adipose tissue, has been reported to be a satiety factor. In addition, it has been shown to increase during pregnancy in maternal blood, parallel to increase in body fat mass…
- Conditions
- Gestational Diabetes Mellitus, Preeclampsia, Placental Hypoxia
- Trial name
- NCT00334841
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Gestational Diabetes, Mobile Application
eHealth in Treatment of Gestational Diabetes (eMOMGDM)
The overall aim of the eMOM GDM-project is to develop and evaluate a novel system to clinical decision making and patient behavior change in treatment of GDM, combining diet, physical activity, sleep, heart rate (e.g.
- Trial name
- eMOMGDM (NCT04714762)
- Testing
- eMOM GDM application
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Type 2 Diabetes Mellitus, Gestational Diabetes
Healthy Moms, Healthy Babies
Poor glucose control during pregnancy is a significant concern for Canadian women with diabetes. This problem is magnified in First Nations women, who have among the highest rates of gestational diabetes (GDM) in the world (up to…
- Trial name
- HMHB (NCT01578460)
- Testing
- Continuous Glucose Monitoring, Glucose Meter
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stewart Harris
Gestational Diabetes Mellitus as Antepartum Condition
Glycemic Impact of Myo-inositol in Pregnancy
Myo-inositol has been shown to decrease the rate of diabetes in pregnancy in European studies. It is not known exactly how this occurs or what it does to the sugar when the supplement is taken.
- Trial name
- NCT02149992
- Testing
- myo-inositol, Continuous glucose monitoring surveillance, Glucose monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabetes, Gestational Diabetes
Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes
This trial is conducted in the United States of America (USA). The purpose of this study is to test whether NovoLog (insulin aspart) is a safe and at least as effective alternative to regular human insulin for the control of…
- Trial name
- NCT00065130
- Testing
- human insulin, insulin NPH, insulin aspart
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Gestational Diabetes, Obesity
Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
This is a prospective, randomized, placebo controlled study with three parallel arms examining the effects of magnesium supplementation in the second trimester of pregnancy.
- Trial name
- NCT01510665
- Testing
- Magnesium citrate, Dietary modification
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Abnormal Glucose Complicating Pregnancy
Diagnosis of Gestational Diabetes Based on a 50-gram Glucose Challenge
The aim of this study is to determine a 1-hour glucose tolerance test (GTT) value at which the diagnosis of gestational diabetes can be made without undergoing a 3-hour test.
- Trial name
- NCT07643987
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Gestational Diabetes Mellitus, Metabolomics Detection
The Study of Biomarker in Early Diagnosis of GDM by Metabolomics
Gestational Diabetes Mellitus (GDM) refers to abnormal glucose metabolism during pregnancy, in which elevated blood glucose is first found during pregnancy and meets the criteria for diabetes.
- Conditions
- Gestational Diabetes Mellitus, Metabolomics Detection, Biomarker in Early Diagnosis
- Trial name
- GDM (NCT05733195)
- Testing
- OGTT test
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus (GDM)
Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes Mellitus
Gestational diabetes mellitus(GDM) is a commom complication during pregnancy and associated with various adverse pregnancy outcomes for both the mother and her offspring.
- Trial name
- NCT03062475
- Testing
- lifestyle intervention with dietary and exercise recommendation
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Mild Gestational Diabetes
Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo
This is a randomized prospective trial which addresses the question of whether use of an oral hypoglycemic agent as an adjunct to diet therapy in women with mild gestational diabetes will result in achieving euglycemia in a…
- Trial name
- NCT00744965
- Testing
- Glyburide
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pre-Eclampsia, Gestational Diabetes
SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India.
Background: Pregnancy-related conditions including hypertensive disorders of pregnancy (HDPs) and gestational diabetes mellitus (GDM) carry independent risks for future cardiovascular disease in women.
- Conditions
- Pre-Eclampsia, Gestational Diabetes, Anemia
- Trial name
- NCT03968952
- Testing
- SMARThealth Pregnancy
- Where
- India
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pregnancy Related, Gestational Diabetes
The Hoosier Moms Cohort
The Hoosier Moms Cohort (HMC) study's goal is to better understand the pathophysiology underlying the development of gestational diabetes mellitus (GDM) in pregnant women and its transition to Type 2 diabetes mellitus in mothers…
- Trial name
- NCT03696368
- Where
- 6 sites in United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Indiana University
Weight Loss, Gestational Diabetes Mellitus in Pregnancy
Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes
The goal of this clinical trial is to evaluate the effectiveness of a 6-month lifestyle intervention compared to Metformin in postpartum women who have delivered a singleton, live born infant within the last 12 weeks to 1 year…
- Conditions
- Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum Care
- Trial name
- GooDMomS2 (NCT06948825)
- Testing
- Metformin Hcl 850Mg Tab, Lifestyle Intervention, Enhanced Lifestyle Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Washington University
Gestational Diabetes
The Role of Umbilical Cord Thickness in Prediction of Fetal Macrosomia in Patients With Gestational Diabetes Mellitus
The aim of this work is the prediction of fetal macrosomia by measuring: 1. HbA1C. 2. Umbilical cord thickness. 3. Interventricular septum thickness.
- Trial name
- NCT02643225
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity
Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness
A pilot randomized control trial (RCT) to examine the efficacy of a culturally tailored mindfulness intervention upon fasting cardiometabolic factors (including markers of glycemic control) and inflammatory gene expression in…
- Conditions
- Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity, Maternal Inflammatory Markers, Maternal Diabetes
- Trial name
- NCT06898658
- Testing
- Mindfulness Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Gestational Diabetes Mellitus in Pregnancy
Effects of Telerehabilitation Exercise Program on Maternal Glycemic Control
Gestational diabetes is in which high blood glucose concentration results from body's inability to create enough insulin to fulfil the needs of pregnancy.
- Trial name
- NCT06452017
- Testing
- Telerehabilitation exercise program, Routine medical care
- Where
- 2 sites in Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pregnancy, Postprandial Glycemia
Whey Protein Pre-load and Postprandial Glycemia in Pregnancy
This pilot study aims to investigate the intake of whey protein prior to carbohydrate intake as an approach to modulate postprandial glucose excursions during pregnancy.
- Trial name
- ProGs (NCT06170905)
- Testing
- Whey protein-preload OGTT
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Pregnant Women, Gestational Diabetes
Education of Pregnant Women at Risk of Gestational Diabetes
There are studies in the literature showing that there is a decrease in the number of pregnant women diagnosed with gestational diabetes and improvements in parameters related to maternal and infant health, with the education to…
- Trial name
- NCT05568277
- Testing
- Education on preventive health behaviors based on Pender's Health Promotion Model
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi