Clinical trials: GERD - PPI Non-responders
Gastro Esophageal Reflux
Effectiveness of Physiologic Testing in PPI Non-Responders
The prevalence of GERD is estimated to be as high as 20% in the US, and up to 50% remain symptomatic on proton pump inhibitor (PPI) therapy.
- Trial name
- NCT03202537
- Testing
- dexlansoprazole
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Northwestern University
Gastroesophageal Reflux Disease
Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)
To understand the dose-response characteristics of PF-00885706 for efficacy in terms of symptomatic relief when used as add-on treatment to esomeprazole 20mg (standard proton pump inhibitor [PPI] treatment), in subjects with…
- Trial name
- NCT00730665
- Testing
- PF-00885706, Esomeprazole
- Where
- 38 sites in Belgium, Brazil and 5 more
- Volunteers
- 81 people
- Sponsor
- Pfizer
GERD - PPI Responders, GERD - PPI Non-responders
Acid Pocket: Position and Aspiration
Gastroesophageal reflux disease (GERD) is a very common condition affecting up to 30% of adults. To date, therapy consists of powerful acid suppression with proton pump inhibitors (PPI).
- Conditions
- GERD - PPI Responders, GERD - PPI Non-responders, Barrett Esophagus, Healthy Volunteers
- Trial name
- NCT02199002
- Testing
- multi-pH-impedance manometry catheter
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Gastro Esophageal Reflux Disease PPI Non-Responders
A Prospective, Observational Study of the PPI Non-responder
Gastroesophageal reflux disease (GERD) is a common chronic condition, affecting approximately 20% of the American adult population. Proton pump inhibitors (PPIs) are now the mainstay of medical therapy for symptoms of GERD.
- Trial name
- NCT03282084
- Testing
- EGD with biopsy, EGD and impedance-pH study on PPI
- Sponsor
- Dartmouth-Hitchcock Medical Center
GERD - PPI Non-responders
Effect of Baclofen in Management of Patients With Gastroesophageal Reflux Disease Symptoms
The goal of this clinical trial is to assess the effect of using baclofen along with conventional treatment in improving GERD symptoms.
- Trial name
- NCT07063576
- Testing
- Baclofen 10mg
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Adnan Imtiaj Rahul