Clinical trials: GI Bleeding
Gastrointestinal Hemorrhage
The Clinical Feature of Ulcer Base Over Time After Prophylactic Argon Plasma Coagulation in Colonic EMR
The prophylactic APC right after colonic EMR doesn't mean the complete coagulation of visible vessel because of injection material.
- Trial name
- NCT02025764
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Gastrointestinal Bleeding, Stress Ulcers
Stress Ulcer Prophylaxis in the Intensive Care Unit
Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported.
- Trial name
- SUP-ICU (NCT02467621)
- Testing
- Pantoprazole, Saline (0.9%)
- Where
- 33 sites in Denmark, Finland and 4 more
- Volunteers
- 3,350 people
- Sponsor
- Dr. Morten Hylander Møller
Gastro Intestinal Bleeding
Factor XIII Activity in Gastrointestinal Bleedings
The aim of this retrospective study is to investigate the relationship between factor XIII activity and the outcome of gastrointestinal bleedings.
- Trial name
- NCT05933135
- Testing
- Factor XIII Injection
- Where
- Austria
- Volunteers
- 97 people
- Sponsor
- Medical University of Graz
Major Haemorrhage
Major Bleeding Risk Associated With Antithrombotics
Prospective, multicenter, observational study with a three-year inclusion period (from January 1, 2012 to December 31, 2015) and a 6-month follow-up
- Trial name
- SACHA (NCT02886533)
- Testing
- Antithrombotic
- Where
- 12 sites in France
- Volunteers
- 6,484 people
- Sponsor
- Rennes University Hospital
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Bowel Cancer, Bowel Diseases, Inflammatory
LuCID - Investigating the Use of a Novel Digital Rectoscope for Community Examinations During COVID-19
The LumenEye scope and CHiP platform will be piloted in a number of clinical settings including remote colorectal clinics. The rationale is to perform an initial pilot study to determine the clinical utility of the LumenEye…
- Conditions
- Bowel Cancer, Bowel Diseases, Inflammatory, Rectal Bleeding
- Trial name
- LuCID (NCT05043363)
- Testing
- LumenEye X1 digital rectoscope
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- Imperial College London
GastroIntestinal Bleeding
Analysis of Blood Metabolomics to Identify Potential Biomarkers of Gastrointestinal Bleeding
Despite advances in gastrointestinal endoscopy and pharmaceuticals, gastrointestinal bleeding is still a significant emergency disease with a high mortality rate of 1.9-5 per 100 people due to excessive bleeding and shock.
- Trial name
- NCT05547360
- Where
- Singapore
- Volunteers
- 32 people
- Sponsor
- National University of Singapore
Peptic Ulcer Hemorrhage
Effect of High-dose Oral Rabeprazole on Recurrent Bleeding After the Endoscopic Treatment of Bleeding Peptic Ulcers
This study is conducted to compare and evaluate the effect of administering a high-dose intravenous proton pump inhibitors or high-dose oral Rabeprazole in preventing recurrent bleeding after the endoscopic treatment of bleeding…
- Trial name
- NCT00838682
- Testing
- omeprazole sodium IV, Rabeprazole
- Where
- 2 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- The Catholic University of Korea
Gastro Intestinal Bleeding, Patient Engagement
Patient Important Gastrointestinal Bleeding in the ICU
This study will engage patients and families to create a definition of what matters most to them about upper gastrointestinal (GI) bleeding.
- Conditions
- Gastro Intestinal Bleeding, Patient Engagement, Family Members
- Trial name
- PIB (NCT05506150)
- Testing
- Interviews
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- McMaster University
Gastrointestinal Hemorrhage
Endoscopic Evaluation of Lower Gastrointestinal Bleeding (GIB) in Patients Presenting With Melena
To evaluate the incidence and etiology of small bowel or large bowel bleeding in patients presenting with melena.
- Trial name
- NCT00164723
- Testing
- Capsule endoscopy
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Chinese University of Hong Kong
Peptic Ulcer With Haemorrhage
Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis
Upper gastrointestinal hemorrhage (UGIH) is common urgency condition.The estimate mortality rate about 7 percent from peptic ulcers disease(PUD).
- Trial name
- NCT05005910
- Testing
- Vonoprazan, PPIs IV infusion
- Where
- Thailand
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Uayporn Kaosombatwattana
Colitis, Ischemic
Study of Ischemic Colitis Compared to Other Diagnoses in Patients With Lower Gastrointestinal Bleeding
The purpose of this study is to study the demographic,laboratory,endoscopic, and outcomes of ischemic colitis patient presented with severe lower gastrointestinal bleeding compared to other diagnoses.
- Trial name
- NCT01078324
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of California, Los Angeles
Acute Lower Gastrointestinal Bleeding
Oral PEG vs. Enema in Urgent Colonoscopy for ALGIB
The main goal of this study is to assess whether the diagnostic efficacy of enema is non-inferior to that of oral polyethylene glycol (PEG) in acute lower gastrointestinal bleeding (ALGIB) patients requiring urgent colonoscopy.
- Trial name
- CANDLE (NCT06254443)
- Testing
- Enema Bowel preparation, PEG Bowel preparation
- Where
- 3 sites in China
- Volunteers
- 144 people
- Sponsor
- Beijing Friendship Hospital
Upper Gastrointestinal Bleeding
Patients With Upper Gastrointestinal Bleeding in Emergency Department
More than 80% of patients with upper gastrointestinal bleeding (UGIB) are hospitalized after their visit to the emergency department (ED). However, some of these hospitalizations do not seem justified.
- Trial name
- UGIB-ED (NCT05927493)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cirrhosis, Liver, Upper Gastrointestinal Bleeding
Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding
The investigators studied the renal function index level in terlipressin treated cirrhotic patients with upper-gastrointestinal bleeding at different time point.
- Trial name
- NCT04358016
- Testing
- Terlipressin, Somatostatin
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Changhai Hospital
Gastrointestinal Hemorrhage, Gastrointestinal Neoplasms
Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
This study evaluates the efficacy of the endoscopic hemostatic powder for the treatment of bleeding from malignant lesions of the upper GI tract.
- Trial name
- NCT02820077
- Testing
- Hemospray (Endoscopic treatment with hemostatic powder)
- Volunteers
- 62 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Colonic Polyp
Prospective, Randomized, Parallel Clinical Controlled Study of Early Diet Opening on Postoperative Gastrointestinal Hemorrhage in Patients With Colonic Polyps
Currently, hemorrhage remains the most common postoperative complication in patients with colon polyps, with an incidence of approximately 1.5%.
- Trial name
- NCT05466903
- Testing
- Early diet opening
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
GastroIntestinal Bleeding
Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding
Acute gastrointestinal bleeding is potentially lethal in liver cirrhosis. Accurate assessment of prognosis is critical in a timely fashion.
- Trial name
- NCT04662918
- Where
- 23 sites in United States, Brazil and 6 more
- Volunteers
- 3,000 people
- Sponsor
- Xingshun Qi
Melena Due to Gastrointestinal Hemorrhage
The Role of Push Enteroscopy in Patients With Passing Melena With Nondiagnostic EGD.
Melena is often caused by upper gastrointestinal (GI) bleeding; therefore, esophagogastroduodenoscopy (EGD) is the first preferred diagnostic tool. However, EGD fails to identify the bleeding source in about 25% of cases.
- Trial name
- NCT06574542
- Testing
- Push enteroscopy (PE), Colonoscopy
- Where
- Thailand
- Volunteers
- 77 people
- Sponsor
- Mahidol University
MALIGNANT GASTROINTESTINAL BLEEDING
TC-325 (HEMOSPRAY™) VS. CURRENT STANDARD OF CARE IN MANAGING MALIGNANT GASTROINTESTINAL BLEEDING: A PILOT STUDY TO INFORM A RANDOMIZED CONTROLLED TRIAL.
Introduction: Gastrointestinal (GI) bleeding arising from malignant tumors is increasingly recognized as a result of oncological advances and improved detection methods, and stems from local vessel damage and tumor invasion with…
- Trial name
- NCT02135627
- Testing
- TC-325 monotherapy on initial endoscopy ± radiation therapy, angioembolization, and/or surgery., Current standard therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre