Clinical trials: GI Bleeding
Gastrointestinal Hemorrhage, Cardiovascular Diseases
Study of the Risk Factors and Outcomes After Gastrointestinal Bleeding
The purpose of this multicenter, two component observational and standardized case-control study is to evaluate risk factors of gastrointestinal (GI) bleeding with a prospective 3-month and 12-month follow-up to examine outcomes…
- Trial name
- NCT02514304
- Where
- Canada
- Volunteers
- 4,745 people
- Sponsor
- Population Health Research Institute
Death
Prognostic Factors in Malignant GI Bleeding Treated With Hemostatic Powder
This is a retrospective study to identify the prognostic factors of the good outcomes in patients who presented with upper GI bleeding from tumor and received Hemospray via endoscopy for hemostatic control.
- Trial name
- NCT03066700
- Testing
- Hemostatic powder
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Gastrointestinal Haemorrhage
Purastat® vs Standard Therapy for Haemostasis During Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is an endoscopic resection technique used to treat superficial neoplasia in the gastrointestinal tract.
- Trial name
- NCT02833558
- Testing
- PuraStat®, Electrocautery
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Gastrointestinal Bleeding
Risk Factors for Rebleeding in Patients With Obscure Gastrointestinal Bleeding
The investigators investigated the rebleeding rate the risk factors for rebleeding after long-term follow-up (≥12 months) in patients who underwent capsule endoscopy for obscure gastrointestinal bleeding.
- Trial name
- NCT01821326
- Volunteers
- 339 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Helicobacter Pylori Infection, Peptic Ulcer Hemorrhage
Diagnostic Performance of CIM for Helicobacter Pylori Infection in Patients With Peptic Ulcer Bleeding
The goal of this cross-sectional study is to evaluate the efficacy of current infection marker (CIM) method for H. pylori detection. The main questions it aims to answer are: To evaluate the efficacy of CIM method for H.
- Trial name
- CIM (NCT06273384)
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gastrointestinal Hemorrhage
Transfusion in Gastrointestinal Bleeding
Aim: To evaluate the feasibility and safety of a restrictive versus liberal red blood cell (RBC) transfusion policy in adult patients admitted with Acute Upper Gastrointestinal Bleeding (AUGIB) in order to inform the design of a…
- Trial name
- TRIGGER (NCT02105532)
- Testing
- Restrictive transfusion policy, Liberal Transfusion Policy
- Where
- United Kingdom
- Volunteers
- 936 people
- Sponsor
- Dr Vipul Jairath
Precancerous Condition
Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding
RATIONALE: A study that evaluates DNA changes and other disease-related health information in patients with Barrett's esophagus, gastroesophageal reflux, or gastrointestinal bleeding may help doctors learn more about the risk…
- Trial name
- NCT00445653
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Massachusetts General Hospital
Atmospheric Pressure; Adverse Effect, GastroIntestinal Bleeding
Gastrointestinal Bleeding and Atmospheric Pressure Relationship
This study aims to investigate whether atmospheric pressure has an effect on upper gastrointestinal bleeding (UGIB), which includes causes such as peptic ulcer disease, esophagitis, gastritis, gastrointestinal varices…
- Trial name
- NCT06515353
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi
Cirrhosis, Liver, Coagulopathy
Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis
The goal of this clinical trial is to compare resuscitation strategies in patients with cirrhosis and gastrointestinal bleeding.
- Conditions
- Cirrhosis, Liver, Coagulopathy, GastroIntestinal Bleeding
- Trial name
- STRATEGIC (NCT05583539)
- Testing
- Thromboelastography
- Sponsor
- Vanderbilt University Medical Center
Bleeding Peptic Ulcer
Multicenter Validation on Predicting Mortality for Patients With Bleeding Peptic Ulcers
This study aimed to validate CU prediction model on mortality for patients with high risk bleeding peptic ulcers after therapeutic endoscopy.
- Trial name
- NCT02245802
- Where
- China
- Volunteers
- 785 people
- Sponsor
- Chinese University of Hong Kong
Hemorrhage
Endoscopy for Bleeding Situations in Surgical Patients
Retrospective analysis of surgical patients with relevant gastrointestinal bleeding situations and indication for endoscopy for bleeding
- Trial name
- NCT04523753
- Testing
- emergency endoscopy
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Ulcerative Colitis
A Study of MDX-1100 in Subjects With Active Ulcerative Colitis
The purpose of this study is to determine the safety and tolerability of the MDX-1100 regimen in subjects with active Ulcerative colitis(UC) and determine the response rate at day 57 in patients administered MDX-1100.
- Trial name
- MDX1100-06 (NCT00656890)
- Testing
- sterile saline for injection, MDX-1100
- Where
- 44 sites in United States, Canada and 6 more
- Volunteers
- 110 people
- Sponsor
- Bristol-Myers Squibb
Bleeding Peptic Ulcer
Surveillance of Bleeding Peptic Ulcer Using Wireless Capsule Endoscopy
To investigate the adjunctive role of "Capsule Endoscope" in continuous endoscopic monitoring and early detection of recurrent ulcer bleeding after endoscopic therapy in patients presenting with bleeding peptic ulcers
- Trial name
- NCT00164827
- Testing
- Endoscopic placement of Capsule endoscope adjacent to the peptic ulcer
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Non-variceal Gastrointestinal Bleeding
Role of Octreotide in Non Variceal Bleeding
The rationale for using somatostatin (octreotide0 is that it has been shown to inhibit the secretion of various gastrointestinal hormones, including gastrin and secretin, which can contribute to the development of non-variceal…
- Trial name
- NCT06062719
- Testing
- PPI group, PPI plus octreotide
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Liver Cirrhosis, Gastrointestinal Bleeding
Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding
Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the…
- Trial name
- SI (NCT06680583)
- Testing
- physical indicators such as shock index relatives
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- St. Martin De Porress Hospital
Bleeding Peptic Ulcer
High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer
To describe the rate of clinically significant rebleeding during 72 hours continuous i.v. infusion of high dose esomeprazole Na in patients in China with primary successful endoscopic haemostatic therapy of a bleeding peptic…
- Trial name
- NCT01757275
- Testing
- Esomeprazole Na, Cimetidine, Esomeprazole Mg
- Where
- 12 sites in China
- Volunteers
- 239 people
- Sponsor
- AstraZeneca
Gastrointestinal Hemorrhage, Variceal Bleeding
Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy
Patients with liver cirrhoses and recent history of variceal bleeding, with HVPG documented non response to medical therapy with non selective beta blockers +/- mononitrates or variceal rebleeding during adequate medical therapy…
- Conditions
- Gastrointestinal Hemorrhage, Variceal Bleeding, Cirrhosis, Encephalopathy
- Trial name
- ENDOvsTIPS (NCT00570973)
- Testing
- endoscopic band ligation, TIPS-Implantation
- Where
- 4 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Colon Cancer, Inflammatory Bowel Diseases
Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure
The study aims to investigate the effect of the optimized bowel preparation and boost regimens on colon capsule endoscopy procedures, specifically on cleanliness and completion rate.
- Conditions
- Colon Cancer, Inflammatory Bowel Diseases, Gastrointestinal Bleed, Colon Polyp
- Trial name
- NCT05726097
- Testing
- polyethylene glycol, sodium phosphate, polyethylene glycol + ascorbic acid
- Where
- Sweden
- Volunteers
- 147 people
- Sponsor
- Region Skane
Gastrointestinal Bleeding
Haemorrhage Alleviation With Tranexamic Acid- Intestinal System
Severe bleeding in the digestive system is a common symptom of many diseases. Each year, about 50,000 people end up in British hospitals because of this problem and about 5,000 of them die.
- Trial name
- HALT-IT (NCT01658124)
- Testing
- Tranexamic Acid
- Where
- United Kingdom
- Volunteers
- 12,009 people
- Sponsor
- London School of Hygiene and Tropical Medicine