Clinical trials: GI Bleeding
Peptic Ulcer Hemorrhage
Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients
The purpose of this phase study is to confirm the efficacy and safety by compare ilaprazole and omeprazole in the treatment and prevention of peptic ulcer bleeding.
- Trial name
- NCT03362281
- Testing
- Ilaprazole, Omeprazole, Ilaprazole tablet
- Volunteers
- 540 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Gastro Intestinal Bleeding
Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding
Upper Gastrointestinal bleed is a common presentation in a medical emergency. Patients generally present with hematemesis, melena or in severe cases hematochezia.
- Trial name
- NCT04788121
- Testing
- Tranexamic acid, Standard of care
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Upper Gastrointestinal Bleed
Optimal Dose of Proton Pump Inhibitors Following an Upper Gastrointestinal Bleed
Despite recommendations from clinical practice guidelines to discharge patients from the hospital on once daily proton pump inhibitors after acute management of UGIB, clinical practice is to use twice daily proton pump inhibitor…
- Trial name
- NCT02235311
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Missouri-Columbia
Overt Obscure Gastrointestinal Bleeding
A Prospective Study Comparing Urgent Video Capsule Endoscopy With Urgent Double-balloon Enteroscopy
Overt obscure gastrointestinal bleeding (OGIB) is a distinct clinical entity with significantly worse outcomes compared with colonic bleeding and upper GI bleeding.
- Trial name
- NCT01654770
- Testing
- video capsule endoscopy, double balloon enteroscopy
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Coronary Occlusion/Thrombosis, Peptic Ulcer Hemorrhage
Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
In a prospective randomised study design to investigate, if a systematic risk factor screening for bleeding ulcer in patients, who following percutaneous coronary intervention (PCI) commence a one year combination treatment with…
- Trial name
- NCT01447498
- Testing
- Screening for risk factors for ulcer bleeding
- Where
- Denmark
- Volunteers
- 2,024 people
- Sponsor
- Odense University Hospital
Gastric Cancer
Effects of Ilaprazole on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone ESD.
This study compared Ulcer healing rate of Ilaprazole 20mg or Rabeprazole 20mg in the patients undergone Endoscopic Submucosal Dissection for Gastric Adenoma or Early Gastric Cancer and investigated Prevention of gastrointestinal…
- Trial name
- NCT02638584
- Testing
- Ilaprazole, Rabeprazole
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
Gastrointestinal Hemorrhage
Glasgow-Blatschford Score Validation in Digestive Hemorrhage
The purpose of this study is to validate the Glasgow-Blatchford score for the stratification of patients with upper gastro-intestinal hemorrhage. This score is easy to calculate.
- Trial name
- NCT01029626
- Testing
- Endoscopy
- Where
- Switzerland
- Volunteers
- 208 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation, GI Bleeding
Left Atrial Appendage Closure With WATCHMAN FLX Device in Recurrent Gastrointestinal Bleeding: The GI-FLX Registry
The GI-FLX Registry is intended to create a registry of patients with a history of Atrial Fibrillation (AF) and Gastrointestinal (GI) bleed who will receive Left Atrial Appendage Closure (LAAC) with WATCHMAN FLX device and…
- Trial name
- NCT06052358
- Testing
- LAAC with Watchman FLX device
- Where
- 4 sites in United States
- Volunteers
- 73 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Anemia, Chronic Liver Disease
Etiopathogenesis of Anemia in Chronic Liver Disease
Anemia is the most common complication of liver cirrhosis and is seen in 75% of cases. The etiology of anemia in liver disease is diverse and often multi-factorial.
- Trial name
- NCT04622449
- Where
- India
- Volunteers
- 125 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Upper GI Bleeding
Detection of Blood in the GI Lumen With HemoPill Acute
The goal of this clinical trial is to learn if the HemoPill acute (trial device) can detect the presence of blood in participants suspected of having upper gastrointestinal bleeding.
- Trial name
- DIRECT (NCT07868068)
- Testing
- HemoPill acute
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stony Brook University
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Warfarin for the first time…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947998
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Warfarin, Antiplatelet drugs
- Where
- United Kingdom
- Volunteers
- 50,299 people
- Sponsor
- Bayer
Upper GI Bleeding, Point of Care Ultrasound
Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy
Emerging studies have evaluated POCUS (Point of Care Ultrasound) for assessing of gastric content prior to anesthesia to reduce the risk of aspiration and demonstrated that POCUS can accurately identify presence of gastric food…
- Conditions
- Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content
- Trial name
- NCT05763745
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Upper Gastrointestinal Bleeding
HFNC Versus Conventional Oxygen Therapy in Prolonged Upper Gastrointestinal Endoscopy in the ICU
Conventional supplemental oxygen therapy (COT) during upper gastrointestinal (UGI) endoscopy via nasal catheter is considered the standard practice in maintenance of oxygenation and prevention of hypoxia.
- Trial name
- NCT06350864
- Testing
- High-flow nasal cannula (HFNC), Conventional nasal oxygen therapy (COT), Upper gastrointestinal endoscopy (UGE) including gastroscopy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Peripheral Arterial Hemorrhage, Trauma
Onyx™ Liquid Embolic IDE Clinical Study
The purpose of this study is to evaluate the safety and effectiveness of Onyx™ LES in the treatment of subjects with active arterial bleeding in the peripheral vasculature outside of the heart and brain.
- Conditions
- Peripheral Arterial Hemorrhage, Trauma, GI Bleed, Ulcer
- Trial name
- NCT06742801
- Testing
- Onyx™ Liquid Embolic System
- Where
- 20 sites in United States
- Volunteers
- 119 people
- Sponsor
- Medtronic Endovascular
Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding
Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding
Acute upper gastrointestinal bleeding is a medical emergency that requires an urgent upper endoscopy to locate and treat the source of the bleeding.
- Conditions
- Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding, Gastrointestinal Hemorrhage
- Trial name
- NCT07749300
- Testing
- Trimebutine Maleate
- Volunteers
- 100 people
- Sponsor
- Assiut University
Upper Gastrointestinal Bleeding
PuraStat® Combined With Adrenaline Versus Standard of Care in Upper Gastrointestinal Bleeding
PuraStat® is a novel gel that offers several advantages over traditional hemostatic powders. Its transparency allows for continuous visualization of the bleeding site, and it can be applied in narrow spaces or in combination with…
- Trial name
- NCT06896409
- Testing
- PuraStat® combined with Adrenaline, Standard of Care
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Tallaght University Hospital
Carbon Footprint in Upper GI Endoscopy, Dyspepsia
The Difference in Carbon Footprint Between Diagnostic Upper GI Endoscopy in Dyspeptic Patients Versus Therapeutic Upper GI Bleeding
The goal of this observational study is to learn about the carbon footprint produced from diagnostic upper GI endoscopy in patients with dyspepsia and therapeutic upper GI endoscopy in patients with non-variceal upper GI…
- Conditions
- Carbon Footprint in Upper GI Endoscopy, Dyspepsia, Non-variceal Upper Gastrointestinal Bleeding
- Trial name
- NCT07261228
- Where
- 2 sites in Thailand
- Volunteers
- 75 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Cirrhosis, Esophageal and Gastric Varices
Efficacy of Rifaximin in Treatment of Cirrhotic Gastroesophageal Variceal Bleeding
The purpose of the study is to evaluate the efficacy of Rifaximin in the treatment of cirrhotic gastroesophageal variceal bleeding.
- Conditions
- Cirrhosis, Esophageal and Gastric Varices, Gastrointestinal Hemorrhage
- Trial name
- EoR-GEVB (NCT02964195)
- Testing
- Rifaximin
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastrointestinal Hemorrhage, Liver Cirrhosis
Efficacy and Safety Study on Nasogastric (NG) Tube in Patients With Upper Gastrointestinal Bleed
Upper gastrointestinal tract hemorrhage (UGIH) remains a major cause of morbidity and mortality . Nasogastric aspiration (NGA) is routinely performed in patients with UGIH to obtain important clinical data and make therapeutic…
- Trial name
- NG (NCT00689754)
- Testing
- nasogastric tube placement
- Where
- United States
- Volunteers
- 282 people
- Sponsor
- University of Texas Southwestern Medical Center
Marginal Ulcer, Chronic Ulcer Disease
Chronic Marginal Ulcers After Gastric Bypass
The purpose of this study is to determine the feasibility, safety, and efficacy of revision gastroplasty along with other adjunct procedures in the treatment of intractable / chronic marginal ulcers after Roux-en-Y gastric…
- Conditions
- Marginal Ulcer, Chronic Ulcer Disease, Persistent Ulcer Disease, Recurrent Ulcer Disease
- Trial name
- ChronicMU (NCT01041079)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco