Clinical trials: GI Disorders
Colorectal Cancer
A Multi Center Study Comparing the Efficacy of CAD EYE and the Standard of Care (White Light )
This study is to assess the sensitivity and added benefits of CADEYE compared to standard care (white-light) in detecting colon polyps in patients undergoing colonoscopy.
- Trial name
- NCT05523271
- Testing
- CAD EYE (Computer Aided Diagnosis ----?
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Gastrointestinal Disease
Casein Glycomacropeptide in Healthy Subjects
Casein glycomacropeptide (CGMP) has anti-inflammatory properties in experimental rodent colitis and using human in vitro inflammation models. Its use as a food ingredient has proven safe and with no influence on dietary intake.
- Trial name
- NCT02832700
- Testing
- Casein glycomacropeptide
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Nasogastric Feeding, Training Family Caregivers
Effectiveness of an Web Application in Enhancing Informal Caregivers' Nasogastric Tube Feeding Competency
The goal of this trial is to determine whether adding a nasogastric tube web application to standard face-to-face caregiver training helps informal caregivers learn nasogastric tube feeding more quickly than standard training…
- Conditions
- Nasogastric Feeding, Training Family Caregivers, Family Caregivers, Informal Caregiver
- Trial name
- NCT07414563
- Testing
- Nasogastric tube web application
- Where
- Singapore
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Blastocystis Infections
Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis
Blastocystis is an anaerobic unicellular protozoal parasite infecting the gastrointestinal tract of humans and a wide range of animals.
- Trial name
- NCT05580393
- Testing
- RFLP analysis of SSU rRNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cholestasis
A Trial of Taurine Supplementation in Parenteral Nutrition 1
The purpose of this study is to investigate whether the inclusion of 1g of intravenous taurine as part of the nitrogen source of parenteral nutrition reduces parenteral nutrition associated cholestatic liver disease, a common…
- Trial name
- NCT00135044
- Testing
- intravenous taurine in nutritional supplement
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Complication of Surgical Procedure, Infections
Pathogenesis of Postoperative Infections and Biomarkers for Early Diagnosis of it
Infections remain a prevalent complication after major abdominal surgery. The common belief that most surgical site infections (SSIs) following elective surgery with modern antiseptic techniques are due to intraoperative…
- Trial name
- NCT06513598
- Testing
- Major visceral surgery for gastrointestinal cancer
- Where
- 2 sites in Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Crohn Disease, Functional Gastrointestinal Disorders
Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodes
The goal of this clinical trial is to compare the gastro-intestinal biopotentials recorded with a homemade device using surface electrodes placed on the abdomen in healthy volunteers, Crohn's disease patients without fibrosis…
- Conditions
- Crohn Disease, Functional Gastrointestinal Disorders, Healthy
- Trial name
- GRELE (NCT06197334)
- Testing
- Gastro-intestinal biopotentials recording
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Steatorrhea, Growth
Tolerance and Digestibility of a New Formula in Healthy Infants
The great majority of infants formula contain fats exclusively from vegetable oil. Nevertheless, the use of both vegetable and dairy lipids is on a real interest to obtain an infant formula closer to the nutritional composition…
- Trial name
- NCT01184378
- Testing
- dairy lipids and soluble milk proteins
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lactalis
Cough, Gastroesophageal Reflux
Longitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal Reflux
Cough is both an important physiologic component of lung defense and a cardinal indicator of disease. For those with chronic cough, defined as cough lasting for more than 3 weeks, the differential diagnosis is broad, including…
- Trial name
- NCT00771706
- Testing
- Proton Pump Inhibitor
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Functional Dyspepsia, Chronic Atrophic Gastritis (CAG)
Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms
Background: Dyspepsia is a common gastrointestinal complaint globally, affecting approximately 21.8% of the population. Among patients presenting with dyspeptic symptoms, over 80% are diagnosed with functional dyspepsia (FD)…
- Trial name
- NCT07250308
- Where
- China
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Healthy Volunteer, Rheumatoid Arthritis
Phenomics in Autoimmune and Inflammatory Diseases
The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and…
- Conditions
- Healthy Volunteer, Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus/Antiphospholipid Syndrome
- Trial name
- TRANSIMMUNOM (NCT02466217)
- Testing
- 1: AID groups, 2: Control groups
- Where
- 2 sites in France
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inflammatory Bowel Disease
Inflammatory Bowel Disease(IBD)Database
This will be a comprehensive epidemiological, clinical, endoscopic and histological database for inflammatory bowel diseases patients in our medical center that will further provide clinical and basic investigations.
- Trial name
- IBD (NCT01266538)
- Where
- Israel
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Colorectal Cancer
Polyp Measurement Device
Colorectal cancer is the second-leading cause of cancer death in the United States. Colorectal cancer screening is recommended to begin at age 50 years for most men and women at average risk for this disease.
- Trial name
- NCT03856255
- Testing
- Micro-Tech Endoscopic Gauge
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Advanced Rectal Cancers
Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers
Hypothesis : Therapeutic intensification by increasing the dose delivered to the tumor by RCMI (conformational radiotherapy by intensity modulation) in order to reduce local relapse, often associated with poor prognosis Primary…
- Trial name
- RADICAL (NCT03200249)
- Testing
- Preoperative chemo-radiation with IG-IMRT dose escalation
- Where
- 2 sites in France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Georges Francois Leclerc
Stage I Colon Cancer AJCC v8, Stage I Rectal Cancer AJCC v8
Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
This clinical trial develops and tests a mobile health (mHealth) intervention to improve adherence to lifestyle recommendations in colorectal cancer (CRC) survivors and their family caregivers.
- Conditions
- Stage I Colon Cancer AJCC v8, Stage I Rectal Cancer AJCC v8, Stage II Colon Cancer AJCC v8, Stage II Rectal Cancer AJCC v8
- Trial name
- NCT06746012
- Testing
- Discussion, Educational Activity, Internet-Based Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Inflammatory Bowel Diseases, Mild Cognitive Impairment
Cognitive Impairment and Affective Mood Disorders in Patients With IBD
The aim is to evaluate the presence of mild cognitive impairment (MCI) in patients with inflammatory bowel disease (IBD). This will be done by cognitive tests.
- Conditions
- Inflammatory Bowel Diseases, Mild Cognitive Impairment, Depression, Anxiety
- Trial name
- COGN-IBD-1 (NCT05760729)
- Testing
- Cognitive testing
- Where
- 3 sites in Romania
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Calprotectin, Inflammatory Bowel Disease
Value of Fecal Calprotectin
For the main goal - the accuracy of calprotectin for the diagnosis of IBD - calprotectin levels will be compared between patients with and without a diagnosis of IBD and the sensitivity, specificity and accuracy will be…
- Trial name
- NCT00577928
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Indiana University
Early Gastric Cancer
Application of Linked Color Imaging（LCI） in Diagnosis of Early Gastric Cancer(EGC)
the purpose of this study is to evaluate application value of LCI in the diagnosis of early gastric cancer.
- Trial name
- NCT03661671
- Testing
- LCI+white light
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
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