Clinical trials: GI Disorders
Infections, Rotavirus, Rotavirus Vaccines
Study to Evaluate Immunogenicity, Reactogenicity and Safety of Rotarix™ Vaccine in Korean Infants
The aim of this study is to assess the immunogenicity, reactogenicity and safety of the human rotavirus (HRV) Rotarix ™ vaccine when administered in healthy infants aged approximately 6-12 weeks at the time of first vaccination.
- Trial name
- NCT00969228
- Testing
- Rotarix ™
- Where
- 18 sites in South Korea
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Inflammatory Bowel Disease
Characterization of Phenotype and Genotype of Early Onset Enteropathies
This study has been set up in order to characterize phenotypes and genotypes of patients with early onset enteropathies. In that goal, Investigators will collect biological samples (mainly blood) of patients suffering from early…
- Trial name
- IMMUNOBIOTA (NCT02614911)
- Testing
- Biological sampling
- Where
- 12 sites in France
- Volunteers
- 1,445 people, healthy volunteers welcome
- Sponsor
- Imagine Institute
Colon Cancer
Study of Colorectal Cancer Screening Options
The investigators propose to evaluate Guardant Health's commercially available colorectal cancer screening assay(Guardant SHIELD) in individuals who are not up to date with CRC screening.
- Trial name
- NCT05987709
- Testing
- GuardantSHIELD Blood Test
- Where
- United States
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Anal Fissure, Microbial Colonization
Microbiota in Chronic Anal Fissure and Its Association With Prognosis
In this study, we will try to answer the following questions: 1. What are the salient features of the microbiota in chronic anal fissure? 2. Are these features associated with prognosis and response to therapy? 3.
- Trial name
- NCT05405634
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lasse Krogsbøll
Gastroparesis
ABCA2 GIRMS Analytical Validation Clinical Performance Study
The purpose of this study is to collect human breath samples for use in a validation study intended to demonstrate equivalent clinical performance measures of new ABCA2 GIRMS (Automated Breath Carbon Analyzer-2 Gas Isotope Ratio…
- Trial name
- NCT04607304
- Testing
- ABCA2 GIRMS
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Bulimia Nervosa, Eating Disorders
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
This study will determine the effectiveness of the antibiotic erythromycin in enhancing gastrointestinal function and decreasing the frequency of binge eating in people with bulimia nervosa.
- Trial name
- NCT00304187
- Testing
- Erythromycin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Sigmoid Colon Cancer
The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome
The purpose of this clinical trial study was to evaluate the prevalence of colon cancer among the symptom (s) of anterior resection syndrome that may occur after surgery in patients for efficacy and safety in Metchnik probiotic…
- Trial name
- NCT03531606
- Testing
- Mechnicov probiotics
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kye Bong-Hyeon
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Gastro Esophageal Reflux, Barrett Esophagus
Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)
Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)
- Conditions
- Gastro Esophageal Reflux, Barrett Esophagus, Erosive Esophagitis
- Trial name
- NCT03228407
- Testing
- Confocal endomicroscopy, Endoscopic biopsies, Mucosal impedance (MI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGuire Research Institute
Inflammatory Bowel Diseases
Phase 1 Study for IPG11406 in Health Volunteer
A phase 1, randomized, double-blind, placebo-controlled, single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics (PK) and food effect of orally administered IPG11406 in healthy adult…
- Trial name
- NCT06255834
- Testing
- IPG11406
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nanjing Immunophage Biotech Co., Ltd
Colorectal Cancer, Metabolic Disease
Impact of Environmental Factors and Metabolomics on Colorectal Cancer.
Colorectal cancer is one of the malignant tumours with high morbidity and mortality worldwide, posing a serious threat to human health.
- Trial name
- NCT06643429
- Testing
- colorectal cancer, colorectal neoplasm
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Dong Peng
Short Bowel Syndrome
Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Rotavirus infection is a common pediatric illness and is the leading cause of severe acute gastroenteritis (vomiting and diarrhea) in infants and young children.
- Trial name
- NCT00767364
- Testing
- Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Michigan
Low Anterior Resection Syndrome, Rectal Cancer
Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome
The study is a multicentre randomized controlled trial with the objective to compare the effect of transanal irrigation with glycerol suppositories in patients suffering from major Low Anterior Resection Syndrome (LARS).
- Trial name
- NCT04087421
- Testing
- Qufora Irrisedo Cone System, Glycerol "OBA"
- Where
- Denmark
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stomach Neoplasms
Irreversible Electroporation(IRE) For Unresectable Stomach Neoplasms
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Stomach Neoplasms.
- Trial name
- IRE (NCT02430636)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Colo-rectal Cancer, Colon Cancer
Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption
Briefly, this is a 28-day dietary intervention study participants will be asked to eat 2 ounces (52 grams) of walnuts every day for 3 weeks, and at the end of the study period they will come in for a colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Cancer, Diet Habit
- Trial name
- NCT04066816
- Testing
- Walnuts
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- UConn Health
IBS - Irritable Bowel Syndrome
Efficacy and Safety of a Probiotic Formulation in Adults With Irritable Bowel Syndrome With Diarrhea (IBS-D)
The purpose of the study is to monitor safety and to evaluate the efficacy of a probiotic formulation on abdominal pain, abnormal defecation, comorbid mood disorders (anxiety and depression) as well as general quality of life in…
- Trial name
- NCT05509725
- Testing
- Probiotic formulation
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Gastric Cancer Patients Treated by Subtotal Gastrectomy
Obestatin Change in Distal Gastrectomy
According to Seoul cancer registry data (2000), cancer became the leading cause of death in Korea, accounting for 23.9% of all deaths and gastric cancer is the most prevalent malignant neoplasm, comprising 20.8% of all cancers.
- Trial name
- NCT00822718
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Colorectal Neoplasms, Colonic Polyp
Adenoma Detection Rate Using AI System in China
The primary aim of this study is to explore the usefulness of Artificial Intelligence system in colonoscopy on adenoma detection rate (ADR). Other aims include to explore the data below when Artificial Intelligence is used.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma
- Trial name
- SinoAIADR (NCT03840590)
- Testing
- CSK AI system, Standard Colonoscopy
- Where
- 4 sites in China
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonoscopy
Implementation of Evidence Based Practices for Colonoscopy: The Strategies to Improve Colonoscopy Study
The purpose of this study is to compare the effect of physician education about evidence based practices for colonoscopy alone, versus physician education plus a multi-component staff implementation strategy to improve adequacy…
- Trial name
- STIC (NCT02723370)
- Testing
- Staff multi-component implementation strategy
- Volunteers
- 46,184 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Irritable Bowel Syndrome (IBS), Children, Only
Butyrate in Children With IBS: Double Blind Placebo Controlled Randomized Clinical Trial
We will perform a randomized, double-blind, placebo-controlled trial to establish whether calcium butyrate relieves symptoms in children with irritable bowel syndrome (IBS).
- Trial name
- BUZIR (NCT04566679)
- Testing
- Dibuzin
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bari
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