Clinical trials: GI-bleeding
Bleeding Peptic Ulcers
Hemostasis of Active Gastrointestinal (GI) Luminal Tract Bleeding
The objective of this study is to show that Hemospray is effective in achieving initial hemostasis and documenting rate of further bleed when compared to standard of care.
- Trial name
- HALT (NCT01306864)
- Testing
- Hemospray Kit
- Where
- 12 sites in Canada, Hong Kong and 2 more
- Volunteers
- 67 people
- Sponsor
- Cook Group Incorporated
Cirrhosis, Esophageal and Gastric Varices
Rifaximin in Patients With Gastroesophageal Variceal Bleeding
The purpose of the study is to evaluate the safety and efficacy of Rifaximin in the treatment of cirrhotic gastroesophageal variceal bleeding.
- Conditions
- Cirrhosis, Esophageal and Gastric Varices, Gastrointestinal Hemorrhage
- Trial name
- RFXM (NCT02991612)
- Testing
- Rifaximin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Zhongshan Hospital
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Pediatric Acute Gastrointestinal Bleeding Registry
The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding.
- Trial name
- TRIAGE (NCT03090945)
- Testing
- This is an obsevational cohort study
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Gastrointestinal Bleeding
Gastrointestinal Bleeding Management
Unlike the management of patients with various forms of accidents (e.g. polytrauma), only a few data exists for the emergency management of patients with acute gastrointestinal bleeding.
- Trial name
- NCT02403076
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Bleeding After GI Endoscopy
Endoscopic Application of Hemostatic Drug Powder in Lower Gastrointestinal Bleeding: A Pilot Study
This clinical trial will enroll patients at National Cheng Kung University Hospital. All patients who are hospitalized for lower gastrointestinal bleeding and undergo colonoscopy will be invited to participate.
- Trial name
- NCT07679139
- Testing
- Tranexamic acid and sucralfate powder spray, Standard endsocopic hemostasis
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Coronary Disease
Cardiovascular Events in Patients With CAD During Emergent Endoscopy for Upper Gastrointestinal Bleeding
Background: Upper gastrointestinal (GI) bleeding, a common disorder encountered at emergency room, may cause hypotension and tachycardia that may in turn result in myocardial ischemia in patients with coronary artery disease…
- Trial name
- NCT00173511
- Testing
- 24 hr Holter monitor
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Gastrointestinal Hemorrhage
Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy
Acute gastrointestinal bleeding is a common medical problem. When patients with gastrointestinal bleeding present with melena (dark, tarry stool) the blood loss is usually originating in the upper gastrointestinal tract…
- Trial name
- NCT02609100
- Testing
- Video Capsule Endoscopy, Colonoscopy, 1.0 X 2.5 cm 'pill' containing a camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Gastrointestinal Bleeding
Occult Obscure Gastrointestinal Bleeding
To test the activity of a polyglucosamine (PG) together with a Standard Management protocol (SM) on the occult and obscure gastrointestinal bleeding (OGIB) and the clinical symptoms in patients suffering from colonic…
- Trial name
- OGIB (NCT03464539)
- Testing
- PG low molecular weight chitosan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Blymum Srl
Peptic Ulcer Hemorrhage
A Study Comparing High Dose Omeprazole Infusion Against Scheduled Second Endoscopy for Bleeding Peptic Ulcer
A prospective randomized study to compare the adjunctive use of high dose omeprazole infusion against scheduled second endoscopy in prevention of peptic ulcer rebleeding after therapeutic endoscopy.
- Trial name
- NCT00164931
- Testing
- Intravenous omeprazole infusion, Scheduled second endoscopy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese University of Hong Kong
GI Bleeding
Hematological Disorders in Patients With GI Angiodysplasia
The aim of this study will be to assess the association between GIT angiodysplasia with any hematological disorders as von Willebrand factor and Prognostic value of von Willebrand factor on patient's outcomes as risk of…
- Trial name
- NCT07183995
- Volunteers
- 55 people
- Sponsor
- Assiut University
Von Willebrand Diseases
Prognostic Value of Implementing VCE on Top in Constitutional VWD-patients With GI-bleeding
Inclusion criteria: Only constitutional VWD-patients fulfilling the inclusion criteria of the French reference center for VWD will be included. Patients with acquired von Willebrand syndrome will not be included.
- Trial name
- NCT04466878
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
GIT - Gastrointestinal Tract Hemorrhage
Endoscopic Findings in Patients With Upper GIT Bleeding
This study aims to identify the causes of upper gastrointestinal bleeding through comprehensive evaluation via upper endoscopy in Assiut University Hospital and contribute valuable insights into effective management strategies.
- Trial name
- NCT06886880
- Testing
- endoscope
- Volunteers
- 100 people
- Sponsor
- Assiut University
Upper GI Bleeding
Validation of Prognostic Accuracy of ABC ( Age, Blood Urea Nitrogen , Co-morbidities ) and Horibe Pre-endoscopy Scoring Systems in Patients With Upper Gastrointestinal Bleeding in Sohag University Hospital .
Upper gastrointestinal bleeding (UGIB) is a common medical emergency with significant morbidity and mortality. Treating physicians are urged to perform rapid diagnosis, careful risk assessment, and effective resuscitation to…
- Trial name
- NCT05876741
- Testing
- history taking , vital signs and labaratory investigations
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Intubation;Difficult, Gastrointestinal Bleeding
Evaluation of Prophylactic Endotracheal Intubation
Upper gastrointestinal (GI) bleeding is defined as patients who either presented with hematemesis or presented with melena along with evidence of hemodynamic compromise.
- Trial name
- NCT03716466
- Testing
- Endotracheal intubation, No airway intervention
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas Southwestern Medical Center
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
Peptic Ulcer
Esomeprazole Versus Pantoprazole to Prevent Peptic Ulcer Rebleeding
The aim of this study is to compare the clinical effectiveness of intravenous esomeprazole and pantoprazole in preventing recurrent bleeding in the patients with high-risk bleeding peptic ulcers after successful standard…
- Trial name
- NCT00881413
- Testing
- Esomeprazole, Pantoprazole
- Sponsor
- Lotung Poh-Ai Hospital
Obscure Gastrointestinal Bleeding, Gastrointestinal Diseases
Assessing Depth of Small Bowel Insertion at Push Enteroscopy by Using Capsule Endoscopy
Bleeding from the gastrointestinal tract can originate from the small bowel. Typically, upper and lower endoscopies are unable to identify the site of bleeding and patients need to undergo special endoscopies with longer cameras…
- Conditions
- Obscure Gastrointestinal Bleeding, Gastrointestinal Diseases, Gastrointestinal Bleed, Angiodysplasia Intestine
- Trial name
- NCT05731388
- Testing
- Push enteroscopy
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Unity Health Toronto
Active Peptic Ulcer Disease/GI Bleeding
Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps for Acute Peptic Ulcer Bleeding
Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection.
- Trial name
- NCT02020603
- Testing
- epinephrine injection plus soft coagulation using hemostatic forceps, epinephrine injection plus argon plasma coagulation
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Kyunghee University Medical Center
Lower GI Bleeding
Safe Discharge in Lower Gastrointestinal Bleeding
The increasing incidence in lower gastrointestinal bleeding (LGIB) leads to a rise in hospital admission. Many LGBI are self-limiting thus the several scores to identify low risk patients suited to outpatient care have been…
- Trial name
- NCT06409988
- Testing
- Safe discharge
- Where
- Spain
- Volunteers
- 398 people
- Sponsor
- Germans Trias i Pujol Hospital
Gastrointestinal Bleeding, Complication of Internal Device
Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device(VAD)Patients
The purpose of this study is to estimate the proportion of Ventricular Assist Device (VAD) patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood test.
- Trial name
- NCT01415869
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic