Clinical trials: Gait Disorders in Old Age
Knee Osteoarthritis
Effect of Footwear on the Clinical, Functional, and Biomechanical Aspects in Elderly Women With Knee Osteoarthritis (OA)
The purpose of this study is to determine whether inexpensive, flexible and non-heeled footwear is effective in improving of clinical, functional and gait biomechanics in elderly women with knee osteoarthritis.
- Trial name
- OA (NCT01342458)
- Testing
- Flexible footwear
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo General Hospital
Cerebrovascular Accident, Accidental Falls
Balance and Gait Characteristics to Predict Accidental Falls in Community-dwelling Stroke Elderly
Background: Accidental falls result in major physical and psychological morbidity in the elderly, especially stroke patients. To get optimal prevention of stroke falls, it is crucial to identify independent risk factors from…
- Trial name
- NCT01825486
- Testing
- accidental falls
- Where
- Taiwan
- Sponsor
- Changhua Christian Hospital
Stroke, Healthy
The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot, gait enhancing and motivating system (GEMS) developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd.…
- Trial name
- NCT03048968
- Testing
- Gait, sit-to-stand movement, stair climbing and treadmill gait, Sit-to-stand movement and treadmill gait, gait enhancing mechatronic system (GEMS)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Aging, Parkinson's Disease (PD)
Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations.
- Trial name
- NCT07568951
- Testing
- Age, Parkinson's disease (PD)
- Where
- 2 sites in Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Vertigo
Effects of Vestibular Habituation and Ocular Reflex Exercises on Vertigo
The aim of this study is to determine the comparative effects of vestibular Habituation and ocular reflex exercises on Gait stability, Dizziness severity, and fear of fall in elderly population with vertigo
- Trial name
- NCT06760975
- Testing
- Vestibular Habituation Exercises, Ocular Reflex Excercises
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Gait Disorders in Old Age, Gait Disorders, Neurologic
Walking With the SAIRE Smart Walker
The current study aims to investigate the effect of walking with the SAIRE smart walker on spatiotemporal parameters and gait kinematics in a population who suffer from difficulties during gait, and compare this to walking with a…
- Conditions
- Gait Disorders in Old Age, Gait Disorders, Neurologic, Walking, Difficulty
- Trial name
- SAIRE (NCT05461677)
- Testing
- SAIRE smart walker, Standard 4-wheeled walker, No walking aid
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Hearing Loss, Gait, Unsteady
Exercise to Improve Balance in Older Adults With Hearing Impairment - a Proof-of-concept Study
Hearing impairment is common in older adults, and recent research points to associations between hearing impairment and balance/mobility.
- Conditions
- Hearing Loss, Gait, Unsteady, Balance; Distorted, Old Age; Debility
- Trial name
- NCT04283279
- Testing
- Virtual reality exercise, Vestibular rehabilitation exercise, Control
- Volunteers
- 60 people
- Sponsor
- Western Norway University of Applied Sciences
Healthy, Thalamic Pain Syndrome
Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
A large proportion of falls in older people occurs when walking. Most studies have recently demonstrated correlation between the variations in spatiotemporal gait parameters and fall risk in elderly and in several diseases.
- Conditions
- Healthy, Thalamic Pain Syndrome, Fallers
- Trial name
- GAITRITE (NCT01443052)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcopenia
A 24-week Off-drug Extension Study in Sarcopenic Elderly Who Completed Treatment in the 6-month Core Study
This extension study was a 24-week off-drug follow-up of the core CBYM338E2202 (NCT ) study and the main objective was to determine the long-term durability of bimagrumab (BYM338) effect after a 6-month treatment period.
- Trial name
- NCT02468674
- Testing
- bimagrumab
- Where
- 30 sites in United States, Australia and 10 more
- Volunteers
- 160 people
- Sponsor
- Novartis Pharmaceuticals
Aging, Inspiratory Muscle Weakness
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of a 4-week inspiratory muscle training (IMT) program on diaphragm muscle thickness, fatty liver density, functional capacity, and quality of life in elderly men…
- Conditions
- Aging, Inspiratory Muscle Weakness, Fatty Liver, Reduced Functional Capacity
- Trial name
- IMT AND ELDERL (NCT07193082)
- Testing
- Experimental Inspiratory Muscle Training (IMT Group), Control Group: No inspiratory muscle training.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Mild Cognitive Impairment
SYNchronizing Exercises, Remedies in Gait and Cognition at Home (SYNERGIC@Home)
Background: Prevention of Alzheimer's Disease and Related Dementias (ADRDs) may be possible for persons with subjective (SCI) or mild cognitive impairment (MCI), or normal cognition and risk factors.
- Trial name
- SYNERGIC@Hom (NCT04997681)
- Testing
- Combined Aerobic Exercise and Resistance Training (AE + RT), Cognitive Training (NeuropeakTM), Control Cognitive Training of Website Searching and Video Watching (WS+V)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of New Brunswick
Diabetic Polyneuropathy
Differential Air Pressure Technology for Treatment of Diabetic Elderly Patients
Aging can be defined as sequential deterioration that occurs in elderly people including weakness, loss of mobility, decline of physical capabilities, increase susceptibility to disease and many other age-related physiological…
- Trial name
- NCT04620265
- Testing
- Antigravity treadmill training 100% weight bearing, Antigravity treadmill training 75% weight bearing, Antigravity treadmill training 50% weight bearing
- Where
- Saudi Arabia
- Volunteers
- 110 people
- Sponsor
- Umm Al-Qura University
Gait Disorders in Old Age
Useability Test to the Wearable Walking-assist Robot (GEMS-H) for Normal Adults Including the Elderly
The purpose of this study is to investigate the userbility and satisfaction of functional gait training with the Gait Enhancing and Motivating System-Hip type (GEMS-H) on locomotor function in normal adults including the elderly.
- Trial name
- NCT04610190
- Testing
- Training with Gait Enhancing and Motivating System (GEMS-H) Robot
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yun-Hee Kim
Late Life Depression, Cognitive Decline
Dopaminergic Dysfunction in Late-Life Depression
Late-Life Depression (LLD), or depression in older adults, often presents with motivational deficits, deficits in performance in cognitive domains including processing speed and executive dysfunction, and mobility impairments.
- Conditions
- Late Life Depression, Cognitive Decline, Depressive Disorder, Treatment-Resistant, Levodopa
- Trial name
- D3 (NCT04469959)
- Testing
- L-Dopa
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Falls, Frailty Syndrome
Effectiveness of a Home-Based Multicomponent Exercise Program With Digital Support in Community-Dwelling Older Adults With Falls
This study evaluates the effectiveness of an 8-week multicomponent exercise program conducted at home with digital support through the VIVIFIL mobile application, compared to a traditional in-person hospital-based exercise…
- Conditions
- Falls, Frailty Syndrome, Gait Disorders, Mobility Limitation
- Trial name
- GAIT2CARE (NCT06936865)
- Testing
- VIVIFIL App Program, Hospital-Based Multicomponent Exercise
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Spanish National Research Council
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
The goal of this clinical trial is to is to test whether Walkasins can help people with peripheral neuropathy maintain their balance better.
- Conditions
- Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in Elderly
- Trial name
- NCT06959277
- Testing
- Walkasins, Fall Prevention Training
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- RxFunction Inc.
Gait, Unsteady, Healthy
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Elderly Adults
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in elderly adults.
- Trial name
- NCT03325998
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Samsung Medical Center
Mild Cognitive Impairment, Cognitive Decline
Effects of Walkasins on Gait Speed of Individuals With Mild Cognitive Impairments
The primary aim of this pilot study is to investigate the effect of Walkasins, a wearable lower-limb sensory prosthesis, on the gait speed and balance function of participants with mild cognitive impairment as measured by the…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Gait Disorders in Old Age
- Trial name
- NCT05723822
- Testing
- Walkasins
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- RxFunction Inc.