Clinical trials: Galectin 3, active
Metastatic Melanoma, Head and Neck Squamous Cell Carcinoma
GB1211 and Pembrolizumab Versus Pembrolizumab and Placebo in Patients With Metastatic Melanoma and Head and Neck Squamous Cell Carcinoma
The purpose of this study is to determine the objective response of GB1211 and pembrolizumab versus pembrolizumab and placebo in patients with advance metastatic melanoma or head and neck squamous cell carcinoma.
- Trial name
- NCT05913388
- Testing
- GB1211, Pembrolizumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Providence Health & Services
Renal Cell Carcinoma (Kidney Cancer), Non Small Cell Lung Cancer
Association Between Galectin-3 Levels and Outcomes in Patients With Renal Cell Carcinoma, Transitional Cell Carcinoma , Non Small Cell Lung Cancer, and Hepatocellular Carcinoma, Treated With PD-1/PDL-1 Inhibitors
1. Background and Rationale:: Galectin-3 (Gal-3) is a β-galactoside-binding protein involved in various biological processes, including cell proliferation, apoptosis, adhesion, and immune regulation.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Non Small Cell Lung Cancer, Hepatocellular Carcinoma, Transitional Cell Carcinoma
- Trial name
- NCT07485114
- Testing
- Serum Gal-3 level, blood count and chemistry included liver function
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Daniel Keizman
Diabetic Neuropathy
DLBS1033 as Adjunctive Therapy for Patients With Diabetic Neuropathy
This study will evaluate the effect of DLBS1033 as adjunctive therapy in patients with diabetic neuropathy. Diabetic neuropathy is a common complication of diabetes that can cause numbness, tingling, pain, impaired nerve…
- Trial name
- NCT07683598
- Testing
- DLBS1033
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- RS H Adam Malik
Vascular Surgical Procedure
Measurement Of NT-proBNP to Predict Outcomes in Surgery
The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery.
- Trial name
- MOBOS (NCT04014647)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Post-operative Atrial Fibrillation, Cardiovascular Diseases
Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft
The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG).
- Conditions
- Post-operative Atrial Fibrillation, Cardiovascular Diseases, Post-pericardiotomy Syndrome
- Trial name
- GNOSIS (NCT06768528)
- Testing
- Galectin-3 dosage
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Thyroid Cancer, Papillary Thyroid Cancer
Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer
Now, the investigators carried out a prospective study enrolling patients with thyroid cancer, who had received ablative thyroidectomy and /or radioactive iodine therapy for two more years.
- Conditions
- Thyroid Cancer, Papillary Thyroid Cancer, Follicular Thyroid Cancer
- Trial name
- NCT04948437
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- National Taiwan University Hospital
Ulcerative Colitis (UC)
The Effects of a Modified Mediterranean Diet on Ulcerative Colitis Patients
Ulcerative colitis is a chronic disease with a significant impact on quality of life where a substantial proportion of patients fails to achieve disease remission.
- Trial name
- OLIVE-UC-1 (NCT07857447)
- Testing
- Modified Mediterranean Diet, Standard Nutritional Guidance
- Where
- Croatia
- Volunteers
- 62 people
- Sponsor
- University Hospital Sestre Milosrdnice