Clinical trials: Gall Stone Disease
Efficacy
ETGBD in Surgically Unfit Patients With Both Choledocholithiasis and Cholecystolithiasis
Cholecystectomy is recommended for patients with both gallbladder (GB) and common bile duct (CBD) stones to prevent recurrent biliary complications, unless there are specific reasons for surgery is considered inappropriate.
- Trial name
- ETGBD (NCT05935969)
- Testing
- ERCP(Endoscopic retrograde choangiopancreatography), ETGBD(endoscopic transpapillary gallbladder drainage)
- Where
- South Korea
- Volunteers
- 302 people
- Sponsor
- Seoul National University Hospital
Choledocholithiasis, Papillary Stenosis
Endoscopic Antegrade Sphincterotomy (ASD) Versus Standard Sphincterotomy
This study compares endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko (Antegrade Sphincterotomy Dovbenko, ASD) with conventional pull-type endoscopic sphincterotomy (EST) in patients undergoing…
- Conditions
- Choledocholithiasis, Papillary Stenosis, Biliary Obstruction, Gallstone Disease
- Trial name
- ASD (NCT04406961)
- Testing
- Endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko., The antegrade sphincterotome developed by Dr. Dovbenko., Endoscopic sphincterotomy.
- Where
- Ukraine
- Volunteers
- 1,521 people
- Sponsor
- Military Medical Clinical Center of the Southern Region, Ukraine
Choledocholithiasis With Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy Following ERCP in Concomitant Gallstones and Common Bile Duct Stones
The present study aimed to compare early and delayed laparoscopic cholecystectomy after ERCP for CBDs and gallstones.
- Trial name
- NCT04475796
- Testing
- Laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Kafrelsheikh University
Gall Stone Disease, Polyp
Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC).
- Trial name
- NCT02317510
- Testing
- combined anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Cholecystitis, Gallstones
Fluorescence Cholangiography During Cholecystectomy - a RCT
The primary objective is to compare the success rates of intraoperative fluorescent cholangiography using indocyanine green versus conventional X-ray cholangiography for the identification of bile duct anatomy during laparoscopic…
- Trial name
- NCT02344654
- Testing
- Indocyanine green, Near-infrared illumination, Urografin
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Choledocholithiasis, Common Bile Duct Calculi
SpyGlass Versus ESWL for Large Common Bile Duct Stones
Overall stone clearance with endoscopic retrograde cholangiopancreatography (ERCP) for choledocholithiasis is a big problem, especially for stones with a diameter greater than 3cm.
- Trial name
- NCT05186350
- Testing
- ERCP+ SpyGlass, ESWL+ ERCP
- Where
- China
- Volunteers
- 65 people
- Sponsor
- First People's Hospital of Hangzhou
Gallstones
Compliance of Clinical Pathways in Elective Laparoscopic Cholecystectomy: Evaluation of Different Implementation Methods
Compliance to the clinical pathway, postoperative complication and total cost of the hospitalisation of patients undergoing elective cholecystectomy for symptomatic cholecystolithiasis were collected over two different periods…
- Trial name
- NCT02667249
- Testing
- clinical pathway
- Volunteers
- 241 people
- Sponsor
- University Hospital Tuebingen
Obesity, Gallstones
Obeticholic Acid in Bariatric and Gallstone Disease
By binding to the nuclear receptor FXR, bile acids not only regulate their own turn-over but presumably also pivotal steps in cholesterol, triglyceride and glucose metabolism as shown in laboratory animals.
- Trial name
- OCABSGS (NCT01625026)
- Testing
- Obeticholic acid
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
Ulcerative Colitis, Crohn Disease
Systems Biology of Gastrointestinal and Related Diseases
This is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and…
- Conditions
- Ulcerative Colitis, Crohn Disease, Obesity, Colon Polyp
- Trial name
- NCT05579444
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Viome
Gallstone, Biliary Stricture
Diagnosis and Percutaneous Treatment of Biliary Tract Diseases
This study aims to implement and optimize the treatment of bile duct diseases in participants not eligible for endoscopic treatment using the Spyglass system, a system suitable for diagnostic and therapeutic endoscopic procedures…
- Conditions
- Gallstone, Biliary Stricture, Biliary Diseases
- Trial name
- NCT06816615
- Testing
- Percutaneous cholangioscopic-assisted treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cholelithiasis
Renalof in the Treatment of Elderly Patients With Gallstones
The purpose of this study is to assess the efficacy and safety of Renalof administration in the treatment of gallstones (cholelithiasis) as determined by ultrasonography and clinical evaluation in elderly patients (aged >65…
- Trial name
- NCT01099319
- Testing
- Renalof
- Where
- Cuba
- Volunteers
- 40 people
- Sponsor
- Catalysis SL
Gallbladder Cancer, Gallstone Disease
EULAT Eradicate GBC
Gallstones are relatively frequent in women and constitute one of the main risk factors for gallbladder cancer (GBC). Currently, GBC diagnosis is mainly based on imaging (ultrasound or abdominal CT) associated with invasive…
- Trial name
- EULAT (NCT06192719)
- Testing
- None, observational study.
- Where
- 36 sites in Argentina, Bolivia and 3 more
- Volunteers
- 15,000 people
- Sponsor
- Centre Paul Strauss
Biliary Stones
Percutaneous Endoscopic Biliary Exploration in Complex Biliary Stone Disease
Patients with complex biliary stone disease are challenging to treat. The investigator present their experience in using urological interventions to treat challenging biliary stones.
- Trial name
- NCT04308993
- Testing
- percutaneous transhepatic choledochoscopy
- Volunteers
- 15 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Common Bile Duct Calculi
Effect of Common Bile Duct Stone Clearance Using Saline Irrigation After Stone Removal: A Prospective Randomized Control Trial.
Retained CBD stone after ERCP is a common problem in clinical practice. This study aimed to evaluate the effect of saline irrigation of common bile duct after complete stone removal considered by ERCP in the reduction of residual…
- Trial name
- NCT05639816
- Testing
- Saline irrigation group
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Endoscopic Retrograde Cholangiopancreatography , Gallstone
Nonradiation-to-endoscopist Endoscopic Retrograde Cholangiopancreatography in Patients With Complexity Level I/II
Radiation exposure may put endoscopists at risk when performing endoscopic retrograde cholangiopancreatography. Although non-radiation endoscopic retrograde cholangiopancreatography was reported in pregnant women in previous…
- Trial name
- NCT02697149
- Testing
- nonradiation-to-endoscopist endoscopic retrograde cholangiopancreatography, standard endoscopic retrograde cholangiopancreatography
- Where
- 2 sites in China
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Laparoscopic Cholecystectomy, Ultrasonography
Ultrasonography vs Intraoperative Laparoscopic Cholecystectomy for Gall Stone Disease
This research is designed to correlate between intraoperative status of gallstone disease patients with their USG findings. The key question it aims to answer is: Does the ultrasonography predict laparoscopic cholecystectomy will…
- Conditions
- Laparoscopic Cholecystectomy, Ultrasonography, Difficult Surgery
- Trial name
- NCT07530874
- Testing
- laparoscopic cholecystectomy
- Where
- Nepal
- Volunteers
- 130 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone
Potential Pulmonary Benefit of Low Pressure Laparoscopic Cholecystectomy in Selected Patients
Standard Pressure Laparoscopic Cholecystectomy，as the standard for cholecystectomy, can lead to about 15% of pulmonary atelectasis.
- Conditions
- Cholecystitis/Cholelithiasis, Cholecystitis; Gallstone, Polyp Gallbladder
- Trial name
- POPLOP (NCT04670952)
- Testing
- Low Pressure Laparoscopic Cholecystectomy, Standard Pressure Laparoscopic Cholecystectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Gallstone
Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis
Subtotal cholecystectomy (STC) is a valuable technique when severe inflammation, fibrosis, or anatomical variations obscure the critical view of safety essential for identifying the cystic duct and artery.
- Trial name
- NCT06969144
- Testing
- cholecystectomy
- Where
- Nepal
- Volunteers
- 1,149 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Cholecystitis; Acute, Choledocholithiasis
Early MRI in Acute GallstonE Disease
This pilot study aims to determine the utility of direct Magnetic Resonance Cholangiopancreatography (MRCP) in the assessment of suspected acute gallstone disease presentations.
- Trial name
- E-MAGED (NCT03709030)
- Testing
- magnetic resonance cholangiopancreatography (MRCP)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Perspectum
Cholecystitis, Acute, Acute Cholangitis
Visualization of the Extrahepatic biliaRy Tree Trial
This study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy.
- Conditions
- Cholecystitis, Acute, Acute Cholangitis, Gallstone Pancreatitis, Choledocholithiasis
- Trial name
- VERT (NCT04922528)
- Testing
- Laparoscopic Cholecystectomy with Fluorescent Cholangiography, Laparoscopic Cholecystectomy with White Light Imaging
- Where
- Canada
- Volunteers
- 340 people
- Sponsor
- University of British Columbia