Clinical trials: Gall Stone Disease
Gallstones
Accuracy of Surgeon-performed Ultrasound in Detecting Gallstones - a Validation Study
Aims: To prospectively investigate the accuracy of surgeon-performed ultrasound for the detection of gallstones. Methods: 179 adult patients, with an acute or elective referral for an abdominal ultrasound examination, were…
- Trial name
- NCT02469935
- Testing
- ultrasound
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Karolinska Institutet
Gallstones
Medical Dissolution of Cholesterol Gallstones Using Oral Aramchol - A Proof of Concept Phase IIa Study
This is a one center, Phase IIa, randomized, double blind, placebo controlled study designed to evaluate the efficacy and safety of two Aramchol doses in subjects 18 to 75 years of age, with newly formed cholesterol gallstones in…
- Trial name
- NCT02325492
- Testing
- Aramchol, Ultrasound
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Galmed Pharmaceuticals Ltd
Gallstones, Appendicitis
Hybrid Transvaginal-Transabdominal Endoscopic Surgery
The is a pilot study to evaluate the safety and efficacy of hybrid transvaginal-transabdominal procedures. Diagnostic peritoneoscopy (visualizing the inside of the abdomen), appendectomy (removal of the appendix), and…
- Conditions
- Gallstones, Appendicitis, Pelvic Pain
- Trial name
- NCT01039129
- Testing
- Endoscopic Cholecystectomy, Endoscopic Appendectomy, Endoscopic Peritoneoscopy
- Where
- United States
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Stone - Biliary
Effect of Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCP
In this prospective study, the investigators assessed the utility of intermittent saline irrigation in reducing the recurrent rate of choledocholithiasis after the endoscopic extraction for common bile duct stones, and it does…
- Trial name
- NCT03937037
- Testing
- Saline irrigation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Gallstone
Impact on Diagnostic Accuracy of a Specific Clinical Ultrasound Practical Teaching
This research proposal is a pilot double-blind randomized control trial evaluating the impact on diagnostic accuracy of a Clinical UltraSound (CUS) teaching for gallbladder assessment using exclusively healthy volunteers for…
- Trial name
- RCTpCUS (NCT04879459)
- Testing
- Practical sessions to learn CUS exclusively on volunteers presenting a healthy gallbladder
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Gallbladder Stone
A Strategy for Gallstone Expulsion Through Dietary Therapy
This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.
- Trial name
- NCT06699030
- Testing
- Functional fatty acids
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Cholelithiasis
Cholecystectomy vs EUS-guided GBD With Stone Removal
In this new era of less invasive procedures, the indications for endoscopic ultrasound (EUS)-guided gallbladder drainage (GBD) are rapidly expanding.
- Trial name
- NCT06038201
- Testing
- LAMS placement for cholecystostomy, Laparoscopic cholecystectomy
- Where
- Ecuador
- Volunteers
- 56 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreaticobiliary Reflux
Pancreaticobiliary Reflux in Patients Without Cholelithiasis
Pancreaticobiliary reflux has been found in patients with cholelithiasis and gallbladder cancer associated with normal pancreaticobiliary union.
- Trial name
- NCT00890201
- Testing
- Gallbladder bile sampling and intraoperative cholangiography
- Where
- Chile
- Volunteers
- 197 people
- Sponsor
- Cirujanos la Serena
Morbid Obesity
Preventive Therapy With Ursodiol to Reduce the Incidence of Gallstones Formation in Patients After Bariatric Surgery
Risk factor of cholelithiasis is rapid weight loss after bariatric surgery and change in the gallbladder function which is secondary to surgery.
- Trial name
- NCT02319629
- Testing
- URSODIOL
- Where
- Israel
- Volunteers
- 266 people
- Sponsor
- HaEmek Medical Center, Israel
Gallstone
Effectiveness of Guided Imagery Meditation in Patients With Laparoscopic Gallstone Surgery
Guided image meditation has been shown to alter the functional circuits of the brain to alleviate pain by mediating breathing and thoughts.
- Trial name
- NCT04390828
- Testing
- Guided Imagery Meditation
- Where
- 2 sites in Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Common Bile Duct Gallstones, Choledocholithiasis
Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla
This study compare 2 techniques to treat difficult bile duct stones endoscopically
- Trial name
- EHL (NCT02703077)
- Testing
- Spyglass, Balloon dilation of the papilla, EHL (electrohydraulic lithotripsy)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Appendicitis, Cholelithiasis
Minimally Invasive Surgery: Using Natural Orifice Translumenal Endoscopic Surgery (NOTES)
This is an observational study of pain and outcomes from patients undergoing transgastric NOTES removal of their appendix or gallbladder.
- Trial name
- NOTES (NCT00531219)
- Testing
- Transgastric Appendectomy, Transgastric Cholecystectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Morbid Obesity, Gallstone
Concomitant Versus Delayed Cholecystectomy for Management of Obesity With Gallstone
in this study we compare the results of concomitant cholecystectomy with bariatric surgery versus delayed cholecystectomy for management of gallstone in obese patients
- Trial name
- NCT04980417
- Testing
- concomitant cholecystectomy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Common Bile Duct Gall Stones
Feasibility of Endoscopic Ultrasound Based Biliary Stone Removal Without Fluoroscopy
To assess the feasibility and success of endoscopic ultrasound (EUS) directed biliary stone removal without use of fluoroscopy. Success for this study will be defined as the successful removal of all stones from the bile duct…
- Trial name
- NCT01678391
- Testing
- Common bile duct stone removal without fluoroscopy.
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- California Pacific Medical Center Research Institute
Lithiasis, Cholecystitis, Acute
Interest of Intravenous Cholangiography With Indocyanine Green in the Context of Laparoscopic Cholecystectomy for Grade 1 and 2 Acute Gallstone Cholecystitis
Acute lithiasis cholecystitis (ALC) is the third most common cause of surgical emergency admission. The initial treatment of ALC associates a medical support and a cholecystectomy, preferentially performed laparoscopically in the…
- Conditions
- Lithiasis, Cholecystitis, Acute, Cholangiopathy
- Trial name
- VIFCAL (NCT04103762)
- Testing
- laparoscopic cholecystectomy, systematic intraoperative cholangiography
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Colorectal Carcinoma, Rectal Prolapse
Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
Robotic assisted surgery has been performed for more than two decades with good success and safety profile. However, there was only one dominating robotic surgical system available in the past which led to high cost for robotic…
- Conditions
- Colorectal Carcinoma, Rectal Prolapse, Prostate Cancer (Adenocarcinoma), Bladder Cancer
- Trial name
- NCT06926374
- Testing
- Robotic surgery using the Sentire Surgical System
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Gall Stone Disease, Polyp
Comparison of Coagulation Factors During Laparoscopic Cholecystectomy
Pneumoperitoneum is formed with CO2 during laparoscopic abdominal operations. Effect of pneumoperitoneum on coagulation factors is not well known.
- Trial name
- NCT02568852
- Testing
- Combined anaesthesia, General anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Cholecystectomy, Adults
ALgerian Cholecystectomy Outcomes and Determinants Study (AL-CODS)
Cholecystectomy, the surgical removal of the gallbladder, is a common procedure performed to treat benign gallbladder diseases such as cholelithiasis (gallstones), cholecystitis (inflammation of the gallbladder), and biliary…
- Conditions
- Cholecystectomy, Adults, Gall Stone, Polyps
- Trial name
- AL-CODS (NCT06481007)
- Volunteers
- 500 people
- Sponsor
- University of Oran 1
Cholelithiasis, Difficult Gallbladder Extraction
Tri-Radial Port Extension for Difficult Gallbladder Extraction
Laparoscopic cholecystectomy is a common operation for gallbladder stones. In some patients, the removed gallbladder is difficult to extract through the umbilical port because it is large, thick-walled, or packed with stones.
- Conditions
- Cholelithiasis, Difficult Gallbladder Extraction, Laparoscopic Cholecystectomy Surgery, Port-Site Fascial Extension
- Trial name
- TPE-LC (NCT07595692)
- Testing
- Vertical Fascial Extension, Horizontal Fascial Extension, Tri-Radial Fascial Micro-Incision
- Where
- Bangladesh
- Volunteers
- 156 people
- Sponsor
- Bangladesh Navy
Choledocholithiasis
Prospective Evaluation of the Covered Self-expandable Metal Stents (CSEMS) for Incomplete Biliary Stone Clearance
The current standard of care for bile duct stone are endoscopic sphincterotomy and stone extraction. Placement of plastic stents is an option for incomplete biliary stone clearance.
- Trial name
- NCT01475864
- Testing
- ERCP with metal stent
- Sponsor
- University of Florida