Clinical trials: Gallbladder Stone
Choledocholithiasis, Cholangiocarcinoma
Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD
When a doctor performs Endoscopic retrograde cholangiopancreatography "ERCP" (Endoscopy to examine the bile duct) a flexible tube is inserted into the mouth and into the stomach.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Benign Stricture of Common Bile Duct
- Trial name
- NCT01673269
- Testing
- Blood culture ( aerobic and anaerobic)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Cholecystitis; Gallstone
Safety of Laparoscopic ChOlecystectomy Performed by Trainee Surgeons With Different CHolangiographic Techniques
Laparoscopic cholecystectomy (LC) gained popularity among general surgeons in 1990s and rapidly become one of the most commonly performed procedures in digestive surgery, with more than one million cholecystectomies being…
- Trial name
- SCOTCH (NCT04863482)
- Testing
- IOC
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Università Politecnica delle Marche
Biliary Disease, Pancreatic Disease
Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope
The purpose of the study is to compare the success rates of procedure success and complication rates in patients undergoing Endoscopic retrograde cholangiopancreatography (ERCP) using two types of currently available endoscopes.
- Conditions
- Biliary Disease, Pancreatic Disease, Choledocholithiasis, Biliary Obstruction
- Trial name
- NCT05429203
- Testing
- Duodenoscope with single-use distal cover, Conventional duodenoscope
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- Stanford University
Common Bile Duct Gallstones
Comparison Between Laparoscopic Common Bile Duct Exploration and Intraoperative ERCP for Management of Common Bile Duct Stones
Many options are available for management of common bile duct stones. the most recent development in this field is single-session approach by one of two methods; laparoscopic common bile duct exploration and intraoperative…
- Trial name
- NCT01189734
- Testing
- laparoscopic common bile duct exploration, laparoscopic cholecystectomy and intraoperative endoscopic sphincterotomy
- Where
- Egypt
- Volunteers
- 248 people
- Sponsor
- Mansoura University
Gallstone Disease, Gallstone; Colic
A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease
The goal of this trial is to assess the effect on the quality of life (QoL) of recommending a fat-free diet versus a balanced WHO diet in symptomatic patients with gallstones and in patients undergoing cholecystectomy for…
- Conditions
- Gallstone Disease, Gallstone; Colic, Gallstone; Cholecystitis, Acute, Cholelithiases
- Trial name
- RADIGAL (NCT06405906)
- Testing
- Fat-free diet, Balanced WHO diet
- Where
- Greece
- Volunteers
- 242 people
- Sponsor
- University Hospital of Crete
Cholelithiases
Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of Complications
Gallstones have been recognised since antiquity and have been found during autopsies of Egyptian mummies. Following the first successful open cholecystectomy in 1882, it was Eric Muhe, a German surgeon, who performed the first…
- Trial name
- NCT06311305
- Testing
- Early Laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Gallstone, Dyslipidemias
Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones
Gallbladder disease is one of the most common diseases of the gastrointestinal tract. Various studies have shown an association between gallstones and an alteration in the serum lipids.
- Trial name
- NCT03804775
- Testing
- Serum lipid profile
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Common Bile Duct Gallstones, Choledocholithiasis
Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla
This study compare 2 techniques to treat difficult bile duct stones endoscopically
- Trial name
- EHL (NCT02703077)
- Testing
- Spyglass, Balloon dilation of the papilla, EHL (electrohydraulic lithotripsy)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Calculus of Gallbladder With or Without Cholecystitis, Laparoscopic Cholecystectomy
Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy
Laparoscopic surgery has become the golden standard for the removal of the gallbladder. Recently, developments have been made so that operations can be performed through a natural orifice instead of the abdominal wall, thus…
- Trial name
- NATCH (NCT01685775)
- Testing
- Transvaginal/transumbilical, Needlescopic with 3 trocars
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Witten/Herdecke
Regional Anesthesia Morbidity, Gallbladder Stone
LaGRA Trial in Laparoscopic Cholecystectomy
This study investigated the effectiveness of a surgeon administered, laparoscopic guided, regional anaesthesia technique.
- Conditions
- Regional Anesthesia Morbidity, Gallbladder Stone, Pain
- Trial name
- LaGRA (NCT03394807)
- Testing
- Levobupivacaine
- Volunteers
- 76 people
- Sponsor
- Health Service Executive, Ireland
Cholesterol Gallstone Dissolution
Synergistic Effects of Natural Oils and Herbal Extracts on Cholesterol Gallstone Dissolution: In Vitro Comparison With Rowachol®
Objective: This study aims to evaluate the effectiveness of a natural mixture (sesame oil, extra virgin olive oil, psyllium extract, and dandelion extract) in dissolving cholesterol gallstones compared to the standard medication…
- Trial name
- NCT06972134
- Testing
- Sesame Oil (SO) at 100 mg/mL in dissolving fluid., Extra Virgin Olive Oil (EVOO) at 100 mg/mL in dissolving fluid., 50% Sesame Oil (SO) + 50% Extra Virgin Olive Oil (EVOO).
- Where
- Syria
- Volunteers
- 55 people
- Sponsor
- University of Duhok
Physical Activity, Breast Neoplasm
The Impact of Physical Activity on the Outcome of Surgery
Over the last decades different life style factors have been established as risk factors for various diseases. The obesity pandemic displays a good example of a disease where great effort is undertaken to characterize risk…
- Conditions
- Physical Activity, Breast Neoplasm, Colorectal Neoplasm, Gall Stones
- Trial name
- NCT01707121
- Where
- 2 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Sahlgrenska University Hospital
Cholecystitis, Gall Stone Pancreatitis
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
Laparoscopic cholecystectomy (removal of the gall bladder via 'keyhole surgery') is a common procedure. This can be performed as an emergency operation when a patient has a complication of gall stones such as acute inflammation…
- Trial name
- NCT01528722
- Testing
- Bupivacaine, Normal saline
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Efficacy
ETGBD in Surgically Unfit Patients With Both Choledocholithiasis and Cholecystolithiasis
Cholecystectomy is recommended for patients with both gallbladder (GB) and common bile duct (CBD) stones to prevent recurrent biliary complications, unless there are specific reasons for surgery is considered inappropriate.
- Trial name
- ETGBD (NCT05935969)
- Testing
- ERCP(Endoscopic retrograde choangiopancreatography), ETGBD(endoscopic transpapillary gallbladder drainage)
- Where
- South Korea
- Volunteers
- 302 people
- Sponsor
- Seoul National University Hospital
Gall Stones (& [Calculus - Gall Bladder]), Anesthesia
Segmental Spinal Anesthesia for Small-incision Cholecystectomy in a Field Hospital
Providing safe and efficient anesthesia and in a field hospital is a challenging situation. This study investigated the feasibility and safety of thoracic spinal anesthesia for small-incision open cholecystectomy in a deployed…
- Trial name
- SPICHOL (NCT05165641)
- Testing
- segmental spinal anesthesia
- Volunteers
- 62 people
- Sponsor
- Avicenna Military Hospital
Gallbladder Malignant Neoplasm
A Case Series on Incidentally Detected Gallbladder Malignancy
A retrospective analysis of data, using the Hospital records of all the patients who underwent cholecystectomy for benign conditions at Osmania General Hospital in a year (2019).
- Trial name
- NCT05606029
- Testing
- Cholecystectomy, extended cholecystectomy
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Osmania Medical College
Gallstone Disease, Bile Duct Diseases
Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions
The goal of this longitudinal observational cohort study is to examine the changes in the composition and diversity of gut microbiome and systemic metabolome in patients with symptomatic gallbladder stones with or without…
- Trial name
- NCT05689255
- Where
- Singapore
- Volunteers
- 65 people
- Sponsor
- Changi General Hospital
Gall Stone Disease, Polyp
Comparison of Coagulation Factors During Laparoscopic Cholecystectomy
Pneumoperitoneum is formed with CO2 during laparoscopic abdominal operations. Effect of pneumoperitoneum on coagulation factors is not well known.
- Trial name
- NCT02568852
- Testing
- Combined anaesthesia, General anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Cholelithiasis
Single Site Robotic Cholecystectomy in Non Selected Patients
This is a study of new technology to allow gallbladder removal through a single small surgical incision. A surgical robot is utilized to help navigate the small space.
- Trial name
- SSRC (NCT01855308)
- Testing
- Single site robotic chole, da Vinci Si Surgical System
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, Davis