Clinical trials: Gallstone
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Gallbladder Cancer, Gallstone Disease
EULAT Eradicate GBC
Gallstones are relatively frequent in women and constitute one of the main risk factors for gallbladder cancer (GBC). Currently, GBC diagnosis is mainly based on imaging (ultrasound or abdominal CT) associated with invasive…
- Trial name
- EULAT (NCT06192719)
- Testing
- None, observational study.
- Where
- 36 sites in Argentina, Bolivia and 3 more
- Volunteers
- 15,000 people
- Sponsor
- Centre Paul Strauss
ERCP, Robot Surgery
Efficacy and Safety of a Novel ERCP Robot in the Treatment of Common Bile Duct Stone
Conventional endoscopic retrograde cholangiopancreatography (ERCP) is performed under fluoroscopic guidance, exposing endoscopists to ionizing radiation and posing risks of work-related musculoskeletal injury.
- Conditions
- ERCP, Robot Surgery, Common Bile Duct Stone
- Trial name
- ERCP (NCT07368335)
- Testing
- Robotic-assisted ERCP, Conventional ERCP
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Common Bile Duct Calculi
Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube Drainage
This observational study aims to compare two techniques for closing the common bile duct incision (choledochotomy) after laparoscopic common bile duct exploration (LCBDE) with T-tube drainage.
- Trial name
- NCT07345663
- Testing
- Modified continuous suture, Interrupted suture
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Yantai Affiliated Hospital of Binzhou Medical University
Choledocholithiasis, Papillary Stenosis
Endoscopic Antegrade Sphincterotomy (ASD) Versus Standard Sphincterotomy
This study compares endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko (Antegrade Sphincterotomy Dovbenko, ASD) with conventional pull-type endoscopic sphincterotomy (EST) in patients undergoing…
- Conditions
- Choledocholithiasis, Papillary Stenosis, Biliary Obstruction, Gallstone Disease
- Trial name
- ASD (NCT04406961)
- Testing
- Endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko., The antegrade sphincterotome developed by Dr. Dovbenko., Endoscopic sphincterotomy.
- Where
- Ukraine
- Volunteers
- 1,521 people
- Sponsor
- Military Medical Clinical Center of the Southern Region, Ukraine
Gallbladder Stone
A Strategy for Gallstone Expulsion Through Dietary Therapy
This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.
- Trial name
- NCT06699030
- Testing
- Functional fatty acids
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Gallstone Disease, Postoperative Pain
TENS for Anxiety, Pain, and Satisfaction After Laparoscopic Cholecystectomy
This study is designed to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) can improve recovery for patients undergoing laparoscopic gallbladder removal surgery (laparoscopic cholecystectomy).
- Conditions
- Gallstone Disease, Postoperative Pain, Surgical Anxiety, Patient Satisfaction After Laparoscopic Cholecystectomy
- Trial name
- TENS-LC (NCT07307703)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Gallstones, Gallstone Attack
The Pro-Chol Study
This prospective clinical cohort study will include patients with gallstones and abdominal pain scheduled for surgery (laparoscopic cholecystectomy).
- Conditions
- Gallstones, Gallstone Attack, Uncomplicated Cholelithiasis, Cholecystolithiasis
- Trial name
- ProChol (NCT07245108)
- Testing
- Laparoscopic cholecystectomy
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Nordsjaellands Hospital
Gallstone Disease
GallRiks ERC Anesthesia Study
Endoscopic retrograde cholangiopancreatography (ERCP) for common bile duct stones (CBDS) removal can be performed under varying levels of sedation.
- Trial name
- NCT07205380
- Testing
- Endoscopic Retrograde Cholangiopancreaticography
- Volunteers
- 121,252 people
- Sponsor
- Karolinska Institutet
Dementia, Depression
Vegetarian Diet and Chronic Degenerative Diseases
To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists
- Conditions
- Dementia, Depression, Cardiovascular Diseases, Stroke
- Trial name
- NCT03470584
- Testing
- Diet Exposure
- Where
- Taiwan
- Volunteers
- 18,064 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Cholecystitis; Gallstone, Cholecystolithiasis
Effect of TENS on Patient Outcomes After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of TENS (Transcutaneous Electrical Nerve Stimulation) on patient outcomes after laparoscopic cholecystectomy.
- Trial name
- TENS (NCT05962853)
- Testing
- Experimental group (Transcutaneous Electrical Nerve Stimulation)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Acute Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
The goal of this clinical trial is to learn if performing gallbladder surgery early is as safe and effective as delaying it for people with acute cholecystitis (a sudden gallbladder infection).
- Trial name
- EDLC-AC (NCT07101315)
- Testing
- Laparoscopic Cholecystectomy
- Where
- 2 sites in Yemen
- Volunteers
- 81 people
- Sponsor
- Sana'a University
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Common Bile Duct Calculi, Laparoscopic Abdominal Surgery
Safety and Feasibility of Early T-tube Cholangiography Performed Within 2 to 3 Days After Laparoscopic Common Bile Duct Exploration
Current clinical evidence indicates that 10-20% of patients with symptomatic cholelithiasis present with concomitant common bile duct stones (CBDS), a clinical scenario requiring tailored therapeutic approaches.
- Conditions
- Common Bile Duct Calculi, Laparoscopic Abdominal Surgery, Cholangiography
- Trial name
- LCBDE (NCT07058740)
- Testing
- early cholangiography
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Piyou Ji
Common Bile Duct Stone
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Common bile duct (CBD) stones are a frequent condition that can lead to severe complications if not treated. The standard approach involves endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone…
- Trial name
- NCT07030829
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Gall Stone, Common Bile Duct Calculi
Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis
- Trial name
- LERV (NCT07008170)
- Testing
- Laparoendoscopic rendezvous
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Cholesterol Gallstone Dissolution
Synergistic Effects of Natural Oils and Herbal Extracts on Cholesterol Gallstone Dissolution: In Vitro Comparison With Rowachol®
Objective: This study aims to evaluate the effectiveness of a natural mixture (sesame oil, extra virgin olive oil, psyllium extract, and dandelion extract) in dissolving cholesterol gallstones compared to the standard medication…
- Trial name
- NCT06972134
- Testing
- Sesame Oil (SO) at 100 mg/mL in dissolving fluid., Extra Virgin Olive Oil (EVOO) at 100 mg/mL in dissolving fluid., 50% Sesame Oil (SO) + 50% Extra Virgin Olive Oil (EVOO).
- Where
- Syria
- Volunteers
- 55 people
- Sponsor
- University of Duhok
Gallstone
Subtotal Cholecystectomy for Difficult Gall Bladder Due to Chronic Cholecystitis
Subtotal cholecystectomy (STC) is a valuable technique when severe inflammation, fibrosis, or anatomical variations obscure the critical view of safety essential for identifying the cystic duct and artery.
- Trial name
- NCT06969144
- Testing
- cholecystectomy
- Where
- Nepal
- Volunteers
- 1,149 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Gallstone
TSH Risk by Extraction Site in Lap Cholecystectomy
The main purpose of this study is to determine whether removing the gallbladder through different incision sites (ports) during laparoscopic surgery affects the risk of developing an incisional hernia.
- Trial name
- NCT06953713
- Testing
- gallbladder extraction umbilical, extracting gallbladder via epigastric port
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Basak
Cholecystitis; Gallstone, Cholecystolithiasis
A (5-5-5-8) Technique for Laparoscopic Cholecystectomy
The aim of this current study is to investigate the effectiveness and safety of a novel technique which is the 5-5-5-8 where the camera port is 5 mm.
- Conditions
- Cholecystitis; Gallstone, Cholecystolithiasis, Cholecystitis, Chronic
- Trial name
- NCT06045546
- Testing
- 5-5-5-8 technique, 10-10-5-5 technique
- Where
- Egypt
- Volunteers
- 524 people
- Sponsor
- ClinAmygate