Clinical trials: Ganglion Cyst
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain
Effectiveness of Bilateral Endoscopic Sphenopalatine Ganglion Block on Postoperative Pain After Septoplasty
The aim of this clinical study will investigate the efficacy of sphenopalatine ganglion block in the treatment of postoperative pain.it will also be learnt whether it reduces the consumption of analgesics in postoperative…
- Trial name
- NCT06695624
- Testing
- Sphenopalatine Ganglion Block
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Healthy Volunteers, Cardiovascular System
Effects of Transcutaneous Electrical Stimulation on the Autonomous Nerve System in Healthy Young People
Cardiovascular disease is one of the most important causes of death and disability in the world. An autonomic imbalance is associated to cardiovascular risks and disorders.
- Conditions
- Healthy Volunteers, Cardiovascular System, Autonomic Nervous System
- Trial name
- ESautonomous (NCT05289817)
- Testing
- Transcutaneous Vagus Nerve Stimulation (t-VNS), Transcutaneous Sympathetic Ganglion Electrical Stimulation (t-SES)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Intraocular Pressure, Osteopathic Manipulative Treatment
Effect of Osteopathic Techiniques on Intraocular Pressure
The purpose of this study is to assess the effects osteopathic techniques at the upper cervical vertebrae or at the sphenopalatine ganglia on the intraocular pressure.
- Trial name
- NCT04863209
- Testing
- Upper cervical manipulation, Sphenopalatine ganglion manipulation
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Postdural Puncture Headache
Study Evaluating Sphenopalatine Ganglion Block (SPGB) for Treatment of Postdural Puncture Headache (PDPH)
Postdural puncture headaches (PDPH) are a consequence of spinal and epidural anesthesia in approximately 1% of cases when performed in obstetric patients.
- Trial name
- PDPH (NCT02365909)
- Testing
- 0.5% bupivacaine, normal saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Anxiety Disorders, Stellate Ganglion Block
Efficacy, Safety and Neural Mechanism of Stellate Ganglion Block in the Treatment of Anxiety. Disorder.
1. In this study, ultrasound-guided Stellate Ganglion Block(SGB) will be used in the treatment of anxiety disorders, combined with relevant scales, HRV indicators and resting state functional magnetic resonance data, to explore…
- Trial name
- NCT06540313
- Testing
- Stellate Ganglion Block
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Nasal Polyps
Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESS
This study aimed to show the effect of sphinopalatine ganglion blockade on surgical field, hemodynamics and postoperative pain in FEES operation.
- Trial name
- NCT04996576
- Testing
- infrazygomatic approach sphinopalatine ganglion block, intranasal injection approach of sphinopalatine ganglion block
- Where
- 2 sites in Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Optical Coherence Tomography, Optical Coherence Tomography Angiography
Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers
Alzheimer disease is hard, long and expensive to diagnose. In order to help the clinician, a new biomarker in Alzheimer disease seems to be very useful.
- Conditions
- Optical Coherence Tomography, Optical Coherence Tomography Angiography, Retinal Thickening, Alzheimer Disease
- Trial name
- RETEVAL (NCT04794634)
- Testing
- Optical coherence tomography (OCT), Optical coherence tomograpohy angiography (OCTA)
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Osteopathic Manual Manipulation of Neurovascular Regulation
Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System
The purpose this study is to determine which manual medicine technique or combination of techniques has the greatest effect on the natural changes in heart rate.
- Trial name
- NCT02193373
- Testing
- Osteopathic Manual Medicine
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Increased Production of Tears
Will a Hands on Technique Applied to the Face Increase the Tear Production in Participants
The goal of this interventional study is to learn if a hands on technique will increase tear production in patients aged 45 and younger, without a history of eye issues.
- Trial name
- NCT07632183
- Testing
- sphenopalatine ganglion release
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Dorsal Root Ganglion
Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion
Here, this study aimed to conduct magnetic resonance neurography (MRN) of the thoracic DRGs in a cohort of healthy individuals. The acquired images will be thoroughly analyzed utilizing 3D-slicer software.
- Trial name
- NCT06177379
- Testing
- healthy volunteer
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Postdural Puncture Headache
Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache
The purpose of this study is to compare a pain block in the midface, versus the traditional, more invasive, therapeutic epidural patch for the treatment of headaches
- Trial name
- NCT03112720
- Testing
- Epidural Blood Patch, Sphenopalatine Ganglion Block
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Post-Dural Puncture Headache
The Sphenopalatine Ganglion Block for Post-dural Puncture Headache
This study aims to determine the efficacy of the sphenopalatine ganglion block in the treatment of post-dural puncture headache in post-partum women at the Brigham and Women's Hospital by measuring VAS scores at times between 0…
- Trial name
- NCT03385772
- Testing
- Sphenopalatine ganglion block
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Post-mastectomy Pain Syndrome
Stellate Ganglion Destruction With Alcohol Versus Thermal Ablation for Chronic Post Mastectomy Pain
Group A: SGB with alcohol injection by ultrasound guidance and C7 level confirmation by fluoroscopy. Group B: Thermal RF; thermal RF neurolysis will be applied with a time of 60 seconds at 80º C, and then will be repeated twice .
- Trial name
- NCT05771103
- Testing
- thermal Radiofrequency neurolysis of Stellate ganglion
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Parkinson's Disease
Retinal Function in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia) and, in extreme cases, a loss of physical movement.
- Trial name
- NCT01010074
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Anesthesia of Mucous Membrane
The Effect of Bilateral Sphenopalatine Ganglion Block on Postoperative Pain in Patients to be Subject to Septorhinoplasty Surgery
The aim of this study is to examine the effects of bilateral sphenopalatine ganglion block on surgical conditions, hemodynamics, intraoperative and postoperative analgesic use, recovery characteristics, and postoperative pain…
- Trial name
- NCT06016816
- Testing
- Bilateral endoscopic sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Stress Disorders, Post-Traumatic
Combining Stellate Ganglion Block With Prolonged Exposure for PTSD
The goal of this clinical trial is to compare the combination of Massed Prolonged Exposure (PE); a behavioral therapy for PTSD) and a stellate ganglion block (SGB; an injection of a local anesthetic into the front of the neck)…
- Trial name
- NCT05889741
- Testing
- Ropivacaine injection, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sleep and Circadian Problems
Effect of Stellate Ganglion Block on Sleep Quality in Patients With Depression
# Brief Summary This clinical research study looks at whether stellate ganglion block (SGB) can improve sleep quality for people with depression. Poor sleep often goes together with depression.
- Trial name
- NCT07836738
- Testing
- Stellate Ganglion Block
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Li Juan
Pain, Phantom
CT-guided Ganglion Impar Block for Management of Phantom Rectal Pain Syndrome
Background:Patients underwent abdominoperineal resection with colostomy may suffered from phantom rectum pain syndrome in the perineal area.In this study, the investigators evaluate the combination between ganglion impar block to…
- Trial name
- NCT03694639
- Testing
- ganglion impar block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University