Clinical trials: Gastrectomy
Bariatric Surgery Candidate, Bone Loss
Healthy Body, Healthy Bones After Bariatric Surgery Trial
One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Bone Resorption
- Trial name
- NCT04279392
- Testing
- Zoledronic Acid 5 mg/Bag 100 ml Inj
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Bariatric Surgery Candidate
Pharmacokinetics of Paracetamol and Antiepileptic Drugs After Sleeve Gastrectomy
Sleeve gastrectomy may affect drug pharmacokinetics in several potential ways. We will measure pharmakokinetics of paracetamol and antiepileptic drugs before and 6 months after sleeve gastrectomy.
- Trial name
- NCT03161509
- Testing
- Paracetamol, Antiepileptic (either carbamazepine, lamotrigine, phenytoin or valproic acid)
- Where
- Israel
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Obesity
Enteroendocrine Cells Before and After Sleeve Gastrectomy
Morbidly obese patients exhibit impaired secretion of satiation hormones which may contribute to the development of obesity. Bariatric surgery is associated with weight loss and dramatic increase in the secretion of satiation…
- Trial name
- NCT02589587
- Testing
- sleeve gastrectomy, no intervention
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Vitamin Deficiencies
Trial Comparing Elan Specialized Bariatric Supplements With Standard Multivitamins in Patients Undergoing Bariatric Procedures
Obesity has escalated to pandemic levels, impacting over 650 million adults globally and significantly contributing to the burden of non-communicable diseases such as type 2 diabetes, cardiovascular disease, obstructive sleep…
- Trial name
- NCT07021170
- Testing
- Elan Believe, Elan Compass, Elan Supreme
- Where
- Egypt
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Obesity, Morbid, Diabete Type 2
Indocyanine Green Test for Evaluation of Perfusion of Staple Line of the Stomach During Laparoscopic Sleeve Gastrectomy
The investigators present the case of a 40-year-old female underwent laparoscopic sleeve gastrectomy. Intraoperative indocyanine green test was performed
- Conditions
- Obesity, Morbid, Diabete Type 2, Cardiac Disease, Vascular Diseases
- Trial name
- NCT05337644
- Testing
- Indocyanine green solution
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Unspecified Effect of Air Pressure
The Effect of PEEP and Intraabdominal Pressure Levels on Cerebral Oxygenation Morbidly Obese.
Background: Study was designed to determine the effect of zero (ZEEP) and 5 mmHg positive end expiratory pressure (5PEEP) on cerebral oximeter levels in morbid obese patients whose undergoing laparoscopic sleeve gastrectomy.
- Trial name
- NCT02920138
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Duzce University
Surgical Procedure, Unspecified
Comparing the Cost Savings Potential of Orogastric Tubes in Laparoscopic Sleeve Gastrectomy
Comparing the operation times and staple loads used between the use of multiple tubes and a bougie versus a one-step suction callibrated system in laparoscopic sleeve gastrectomy.
- Trial name
- VS1 (NCT03239405)
- Testing
- Suction callibrated system
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boehringer Labs LLC
Pain, Postoperative
Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement
Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort.
- Trial name
- NCT03071991
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Morbid Obesity
Laparoscopic Gastric Plication Compared With Laparoscopic Sleeve Gastrectomy
The study must be performed in 100 patients suffering from morbid obesity, the procedure will be performed under general anesthesia doing two or three layers of suture to achieves gastric imbrication until transform the stomach…
- Trial name
- LGP (NCT01293877)
- Testing
- Laparoscopy surgery for morbid obesity
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bikkur Holim Hospital
Laparoscopic Sleeve Gastrectomy, Postoperative Nausea and Vomiting
Randomized, Controlled, Single-blind Exploratory Study of the Efficacy and Safety of Wrist and Ankle Acupuncture Intervention on Nausea, Vomiting and Pain After Sleeve Gastric Surgery in Women
PONV is the most common clinical presentation after surgical procedures beyond pain. A retrospective study of our center found that the postoperative incidence of LSG was 77.4%.
- Trial name
- NCT05873270
- Testing
- Wrist and ankle acupuncture
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LILIAN GAO
Pain, Postoperative
Comparison of QLB Block and TAP Block in Morbid Obese Patients
Quadratus lumborum block (QLB) and Transversus abdominis plane (TAP) blocks are regional anesthesia techniques that are frequently used to reduce postoperative pain and are an important part of the current analgesic regimen for…
- Trial name
- NCT05820620
- Testing
- TAP block, QLB block, Control Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Biruni University
Bariatric Surgery Candidate, Perioperative Complication
Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery
Post-operative nausea and vomiting (PONV) is one of the leading causes of patient morbidity after laparoscopic bariatric surgeries.
- Conditions
- Bariatric Surgery Candidate, Perioperative Complication, Nausea, Vomiting, Postoperative
- Trial name
- PONV (NCT05087615)
- Testing
- Metoclopramide, Ondansetron, Metoclopramide and Ondanteron
- Where
- Iran
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Laparoscopic Sleeve Gastrectomy
Reinforcement Method in Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy is a technically simple popular bariatric operation with acceptable results. Leaks can occur in long staple lines; therefore, variable reinforcement methods are used.
- Trial name
- NCT03051919
- Testing
- observation
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteoporosis, Sarcopenia
Bone Microstructure After Gastrectomy Evaluating by Using HR-pQCT
Osteoporosis after gastrectomy, which is characterized by both the loss of bone mass and the deterioration of bone architecture, is a serious complication in the long course after gastrectomy.
- Conditions
- Osteoporosis, Sarcopenia, Gastric Cancer
- Trial name
- NCT03398226
- Where
- Japan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nagasaki University
Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery
This study aims to evaluate the possible efficacy of baclofen on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.
- Conditions
- Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy, Morbid Obesity
- Trial name
- NCT05516953
- Testing
- Baclofen Tablets
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Postoperative Pain
The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
The aim of this study to test hypothesis that addition of dexmedetomidine to fentanyl based intravenous patient controlled analgesia (PCA) improves postoperative pain compared with conventional thoracic epidural and intravenous…
- Trial name
- NCT02325882
- Testing
- Dexmedetomidine, Fentanyl 1, Fentanyl 2
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Compassion, Bleeding
Comparison of Omentopexy and Clips on the Staple Line During Laparoscopic Sleeve Gastrectomy
Background: Bleeding through the staple line has been reported as one of the most common staple-related complications in laparoscopic sleeve gastrectomy (LSG).
- Conditions
- Compassion, Bleeding, Nausea, Postoperative, Readmission
- Trial name
- NCT06219668
- Testing
- Omentopexy group
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital