Clinical trials: Gastrectomy
Esophagogastric Junction Adenocarcinoma, Siewert Type II Adenocarcinoma of Esophagogastric Junction
A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Ⅱ AEG
Objective: To evaluate the safety, feasibility and clinical efficacy of transthoracic single-hole assisted laparoscopic radical gastrectomy for Siewert Type Ⅱ adenocarcinoma of esophagogastric junction.
- Trial name
- NCT04423354
- Testing
- Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Type Ⅱ Adenocarcinoma of Esophagogastric Junction
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
End Stage Renal Disease
Pharmacokinetics of Immunosuppressants in Renal Transplant Candidates Who Have Undergone Laparoscopic Sleeve Gastrectomy
The purpose of this study is to evaluate how quickly and to what extent different immunosuppressants are absorbed into the blood (this is called pharmacokinetics) in renal transplant candidates who have undergone a laparoscopic…
- Trial name
- NCT02221583
- Testing
- Astagraf XL, Prograf, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Cincinnati
Peristaltic Direction, Roux-en-Y Gastrointestinal Anastomosis
Study on the Peristaltic Direction of GI Anastomosis in Roux-en-Y Reconstruction
The aim of this study is intending to provide the optimal procedures of the peristaltic direction of gastrointestinal anastomosis in Roux-en-Y reconstruction after distal curative gastrectomy for gastric cancer, which can provide…
- Conditions
- Peristaltic Direction, Roux-en-Y Gastrointestinal Anastomosis, Gastric Cancer
- Trial name
- NCT04801459
- Testing
- Direction procedure of gastrointestinal anastomosis in Roux-en-Y reconstruction
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Rhabdomyolysis, Acute Kidney Injury
Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure
This prospective clinical trial aimed to assess the usefulness of the usage of a vacuum mattress during laparoscopic sleeve gastrectomy (LSG) in the reduction of levels of rhabdomyolysis markers (myoglobin, creatine kinase…
- Conditions
- Rhabdomyolysis, Acute Kidney Injury, Bariatric Surgery Candidate
- Trial name
- NCT06338423
- Testing
- vacuum mattress, Standard Mattress
- Where
- Poland
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Postoperative Pain
Effect of OFA in Laparoscopic Gastrectomy
The investigator will examine the effects of opioid free anesthesia in patients undergoing laparoscopic gastrectomy. The investigator expect that opioid free anesthesia will reduce postoperative pain and opioid consumption.
- Trial name
- NCT05076903
- Testing
- OFA, Control
- Where
- 2 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Bariatric Surgery Candidate, Weight Loss
A Comparison of Two Regional Techniques for Bariatric Sleeve Gastrectomy
Regional anaesthetic techniques, or nerve blocks, are commonly used to provide postoperative pain relief for patients undergoing surgery.
- Conditions
- Bariatric Surgery Candidate, Weight Loss, Surgery
- Trial name
- NCT05839704
- Testing
- Bilateral Erector Spinae Plane Block, Abdominal Wall Blocks
- Where
- Ireland
- Volunteers
- 70 people
- Sponsor
- University College Hospital Galway
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
Metabolic Flux Analysis in Metabolic Dysfunction-Associated Steatotic Liver Disease
This prospective, single-center pilot study will evaluate metabolic flux dysregulation in adults with obesity and suspected or confirmed metabolic dysfunction-associated steatotic liver disease (MASLD) who are scheduled for…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, Obesity, Bariatric Surgery
- Trial name
- MASLD (NCT07760909)
- Testing
- Bariatric surgery, Stable isotope tracer infusion, MRI/MRE
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Bariatric Surgery
Efficacy and Safety of Ciprofol in Laparoscopic Sleeve Gastrectomy
To evaluate the efficacy and safety of ciprofol for the induction of general anesthesia in obese patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- NCT05522998
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 212 people
- Sponsor
- The Third People's Hospital of Chengdu
Weight Loss
Pre- and Postoperative Probiotics Administration in Patients Undergoing Sleeve Gastrectomy
Patients will be randomized into 2 groups: G1: Patients undergoing sleeve gastrectomy as bariatric procedure and receiving pre- and postoperative probiotics G2: Patients undergoing sleeve gastrectomy as bariatric procedure and…
- Trial name
- NCT04367428
- Testing
- Administration of probiotics
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Gastric Cancer
Preventive Use of PIPAC in Locally Advanced Gastric Cancer.
Gastric cancer is the fifth most common cancer worldwide and the third leading cause of cancer-related mortality. In patients with locally advanced gastric cancer, multimodal treatment strategies, including perioperative…
- Trial name
- NCT06784765
- Testing
- Intervention Group, Control Group
- Where
- Kazakhstan
- Volunteers
- 160 people
- Sponsor
- National Research Oncology and Transplantology Center, Kazakhstan
Polycystic Ovary Syndrome
The Changes of Body Fat Distribution in Obese Patients With PCOS After LSG
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04690634
- Testing
- laparoscopic sleeve gastrectomy (LSG)
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Shanghai 10th People's Hospital
Gastric Cancer
Intraoperative Adverse Events in Robotic Radical Gastrectomy for Gastric Cancer
Surgical quality control is a crucial determinant of evaluating the tumor efficacy. We assess the ClassIntra grade for quality control and oncological outcomes of robotic radical surgery for gastric cancer (GC).
- Trial name
- NCT05999019
- Testing
- robotic surgery
- Volunteers
- 366 people
- Sponsor
- Fujian Medical University
Bariatric Surgery Candidate, Glucose Metabolism Disorders
The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy
The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for improved insulin secretion and…
- Trial name
- NCT05189353
- Testing
- Ghrelin
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Postoperative Pain
Investigating the Analgesic Efficacy and Ease of Perfomance of Modified Throracoabdominal Plane Block and Comparing it With Erector Spinea Plane Block in Laparacopic Sleeve Gasterctomy Surgeries
Interest in surgical weight loss interventions continues to rise in the face of what has been dubbed the obesity epidemic. The most popular of these weight loss interventions is laparoscopic sleeve gastrectomy, which has proven…
- Trial name
- NCT07654556
- Testing
- Bupivacaine 0.25% (isobaric), Bupivaciane 0.25% (Isobaric)
- Volunteers
- 64 people
- Sponsor
- Cairo University
Gastric Cancer
Pilot Study for High Output Drainage Removal After Gastrectomy
*Objective: The study aims to evaluate whether there is a difference in intra-abdominal complication rates between patients discharged with or without a drainage tube following gastrectomy with high postoperative drainage…
- Trial name
- NCT06690112
- Testing
- Arm I (Drainage tube removal)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gangnam Severance Hospital
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge.
- Conditions
- Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
- Trial name
- NCT04644445
- Testing
- Bariatric Full Liquid Diet
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Colorectal Neoplasms, Gastrectomy
The Impact of Laparotomy and Analgesia Methods on Diaphragm
Major abdominal surgeries are traditionally performed via laparotomy. Analgesia is routinely administered during the postoperative period.
- Trial name
- NCT06403540
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Obesity and Overweight, Nutritional Deficiency
Nutritional Health and Satisfaction After Bariatric Surgery: a Five-Year Retrospective Study
A retrospective study analyzing long-term outcomes of metabolic bariatric surgery (MBS) with a focus on weight loss, nutritional deficiencies, and patient satisfaction over a five-year follow-up.
- Conditions
- Obesity and Overweight, Nutritional Deficiency, Bariatric Surgery
- Trial name
- NCT06664580
- Testing
- Metabolic Bariatric Surgery Procedures
- Volunteers
- 249 people
- Sponsor
- San Raffaele Telematic University
Stomach Cancer
Effect of Mosapride Citrate on Gastrointestinal Motility After Laparoscopic Gastrectomy
"Mosapride citrate is a 5-hydroxytryptamine 4 receptor agonist, and is widely used as an agent to increase intestinal motility. Mosapride citrate has been demonstrated in in vitro and in vivo studies to increase both gastric and…
- Trial name
- NCT04493125
- Testing
- Mosapride citrate
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Gangnam Severance Hospital
Early-stage Breast Cancer, Obesity
BAriaTric Surgery After Breast Cancer Treatment (BATS)
This is a feasibility study to gain an understanding of the willingness of women with a history of early stage breast cancer and current obesity to enroll in a weight-loss study, accept an assigned intervention (bariatric surgery…
- Trial name
- NCT03946423
- Testing
- Bariatric Surgery with Sleeve Gastrectomy, Lifestyle Intervention
- Sponsor
- Masonic Cancer Center, University of Minnesota