Clinical trials: Gastrectomy for Gastric Cancer
Metastatic Gastric Cancer, Gastric Cancer
Cytoreductive Gastrectomy After Systemic Therapy Versus Systemic Therapy Alone For Limited Metastasis Gastric Cancer
The results of the current studies to determine the optimal strategy for metastatic gastric cancer remain contrversial worldwide.
- Conditions
- Metastatic Gastric Cancer, Gastric Cancer, Systemic Therapy, Cytoreductive Gastrectomy
- Trial name
- CYGAS-GC (NCT06768463)
- Testing
- Cytoreductive Gastrectomy
- Where
- Vietnam
- Volunteers
- 250 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Stomach Neoplasm
Omentum Preservation Versus Complete Omentectomy in Gastrectomy for Gastric Cancer
Curative therapy for gastric cancer usually consists of perioperative chemotherapy and a radical (R0) gastrectomy. A radical resection includes a modified D2 lymphadenectomy, and, generally, a complete omentectomy, to ensure the…
- Trial name
- OMEGA-2 (NCT05180864)
- Testing
- Gastrectomy
- Where
- 16 sites in Germany, Italy and 2 more
- Volunteers
- 654 people
- Sponsor
- Amsterdam UMC
Gastric Cancer
The Safety of Totally Laparoscopic Versus Laparoscopy-Assisted Total Gastrectomy.
To compare the short-term surgical safety and postoperative quality of life of totally laparoscopic versus laparoscopy-assisted total gastrectomy and to evaluate the superiority of totally laparoscopic total gastrectomy.
- Trial name
- NCT04351321
- Testing
- Totally Laparoscopic Total Gastrectomy, Laparoscopy-Assisted Total Gastrectomy
- Volunteers
- 560 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gastric Cancer
Feasibility Study of Laparoscopy-assisted D2 Distal Gastrectomy to Treat Advanced Gastric Cancer
The purpose of this study is to evaluate the oncological feasibility of laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for advanced gastric cancer.
- Trial name
- COACT_1001 (NCT01088204)
- Testing
- laparoscopy assisted distal gastrectomy, open distal gastrectomy
- Where
- 7 sites in South Korea
- Volunteers
- 204 people
- Sponsor
- National Cancer Center, Korea
Adhesive Intestinal Obstruction
Anti-adhesion Effect of GUARDIX-SGⓇ in Gastric Cancer Surgery
This study is to evaluate the efficacy of GUARDIX-SGⓇ for patients with gastrectomy in Korea and the investigators hypothesized applying of adhesive preventing agent would reduce incidence of adhesive obstruction after…
- Trial name
- NCT02198898
- Testing
- GUARDIX-SG
- Where
- South Korea
- Volunteers
- 224 people
- Sponsor
- The Catholic University of Korea
Remnant Gastric Cancer
The Safety, Feasibility and Oncological Outcomes of Laparoscopic Completion Total Gastrectomy for Remnant Gastric Cancer
This study aims to investigate the safety, feasibility, and long-term oncological outcomes of laparoscopic completion total gastrectomy for remnant gastric cancer.
- Trial name
- NCT02792881
- Testing
- Laparoscopic completion total gastrectomy with D2 lymphadenectomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University
Gastric Cancer (GC), Malnutitrion
Combined Oral and Parenteral Nutritional Therapy After Gastrectomy for Gastric Cancer
Patients undergoing gastrectomy for gastric cancer frequently experience insufficient oral intake during the postoperative recovery period because of reduced gastric capacity, early satiety, and gastrointestinal symptoms.
- Trial name
- BRIDGE-GC (NCT07604857)
- Testing
- Oral Nutritional Supplementation, Parenteral Nutrition, Standard Postoperative Nutritional Care
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Kyo Young Song
Stomach Neoplasms
Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer
Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall…
- Trial name
- NCT04439812
- Testing
- Observation
- Volunteers
- 267 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Stomach Neoplasm, Cardiovascular Diseases
Pharmacokinetics of Oral Antiplatelet Agents After Distal Gastrectomy
This study is aimed to investigate the changes in pharmacokinetics and efficacy of antiplatelet agents before and after distal gastrectomy in gastric cancer patients taking oral antiplatelet agents for primary or secondary…
- Conditions
- Stomach Neoplasm, Cardiovascular Diseases, Cerebrovascular Disease
- Trial name
- NCT05543863
- Testing
- Platelet function testing
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Stomach Neoplasms
Randomized Controlled Trials on Clinical Outcomes of Totally Laparoscopic Versus Laparoscopy Assisted Total Gastrectomy for Gastric Cancer
The purpose of this study is to explore clinical outcomes of totally laparoscopic versus laparoscopy assisted total gastrectomy for gastric cancer.
- Trial name
- NCT03006263
- Testing
- Totally Laparoscopic Total Gastrectomy, Laparoscopy Assisted Total Gastrectomy
- Volunteers
- 110 people
- Sponsor
- Fujian Medical University
Gastric Cancers
Analysis of Lymph Node Metastasis and Tumor Deposit in the Short Gastric Mesentery Following Total Gastrectomy for Gastric Cancer
This study aims to explore lymph node metastasis in the short gastric mesentery following total gastrectomy with D2 lymphadenectomy plus complete mesogastric excision, providing evidence-based medicine for standardizing lymph…
- Trial name
- zytg001 (NCT06728878)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jichao Qin
Hereditary Diffuse Gastric Cancer
Liquid Biopsies for the Personalized Management of Patients with Hereditary Diffuse Gastric Cancer
Activating somatic mutations and methylation profiles identified by liquid biopsies could identify CDH1 and CTNNA1 pathogenic variants carriers with invasive diffuse gastric cancer undetectable by upper G-I endoscopy.
- Trial name
- LISA-HDGC (NCT04253106)
- Testing
- Liquid biopsies (blood, gastric fluid).
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus Type 2 in Nonobese, Gastric Cancer
Safety and Efficacy of Long Limb Roux-en Y Reconstruction
We grafted the concept of metabolic surgery (long limb Roux-en Y reconstruction) into gastric cancer surgery. This study aimed to investigate the safety and efficacy of long limb Roux-en Y reconstruction after gastrectomy in…
- Trial name
- LoLiRoRe (NCT01373346)
- Testing
- Long limb Roux-en Y reconstruction
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Gangnam Severance Hospital
Gastric Cancer
Comparison With Open and Totally Laparoscopic Gastrectomy for Gastric Cancer
In gastric cancer, laparoscopic gastrectomy is commonly performed in Asian countries. In other regions where tumor incidence is relatively low and patient characteristics are different, developments in this issue have been…
- Trial name
- NCT04481828
- Testing
- gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Gastric Cancer, Reflux Esophagitis
Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy
The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions.
- Trial name
- NCT06475170
- Testing
- proximal gastrectomy combined with 'λ+α' double-tract anastomosis
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Northern Jiangsu People's Hospital
Gastric Cancer
Fast Track Surgery With Laparoscopic-assisted Gastrectomy for Advanced Gastric Cancer: a Randomized Controlled Trial
The purpose of this study is to to investigate the feasibility and safety of fast-track surgery when combined with laparoscopic-assisted gastrectomy for advanced gastric cancer patients.
- Trial name
- FTSlapAG (NCT01955096)
- Testing
- fast-track surgery, conventional postoperative care
- Volunteers
- 61 people
- Sponsor
- Quan Wang
Early Gastric Cancer
Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer
The investigators compared the perioperative, oncological, functional and immunological outcomes of endoscopic submucosal dissection against laparoscopic assisted gastrectomy for treatment of early gastric cancer.
- Trial name
- LGE (NCT03136354)
- Testing
- Endoscopic Submucosal Dissection, Laparoscopic assisted Gastrectomy
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Gastric Cancer, Gastrointestinal Cancer
Comparison of Outcomes of Multiple Platforms for Assisted Robotic - Gastrectomy
The object of this exploratory clinical trial is to evaluate intra and post-operative complications in a population that underwent Robotic Gastrectomy, with multiple platforms: DaVinci; Hugo; Versius.
- Conditions
- Gastric Cancer, Gastrointestinal Cancer, Neoplasms, Gastric Diffuse Adenocarcinoma
- Trial name
- NCT06362070
- Testing
- DaVinci® Surgical System, Hugo™ RAS System, Versius® Robotic Surgery System
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Gastric Cancer, Peritoneal Metastases
Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer
Data demonstrating the efficacy of PIPAC in patients with regionally advanced gastric cancer with positive peritoneal cytology and/or minimal peritoneal disease is limited due to the relatively recent development of this…
- Conditions
- Gastric Cancer, Peritoneal Metastases, Chemotherapy Effect
- Trial name
- SPECTRA (NCT05318794)
- Testing
- Doxorubicin and Cisplatin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Gastric Cancer, Complication of Surgical Procedure
Study About no Antimicrobial Prophylaxis in Totally Laparoscopic Distal Gastrectomy
Laparoscopic gastrectomy has fewer infectious complications compared to open surgery. Recently, the incidence of postoperative infectious complications was greatly reduced due to the development of surgical techniques and…
- Trial name
- KSWEET-03 (NCT03802097)
- Testing
- No use of antimicrobial prophylaxis, Use of antimicrobial prophylaxis
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Korean South West East Gastric Surgery Group