Clinical trials: Gastric Bypass
Bariatric Surgery, Osteoporosis
Skeletal Health in Bariatric Surgery Patients
The investigators propose a prospective cohort trial that will help to understand the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in pre- and post-menopausal female bariatric patients.
- Conditions
- Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass
- Trial name
- NCT03331536
- Testing
- Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Morbid, Surgery
Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
The aim of the study is to compare two different bariatric procedures performed in patients with 65 years or more: gastric bypass and sleeve gastrectomy.
- Conditions
- Obesity, Morbid, Surgery, Elderly
- Trial name
- BaSE (NCT03339791)
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Minimally Invasive Surgical Procedure, Laparoscopic Gastric Banding
Evaluation of Safety and Efficacy of the EndoLift Liver Retractor
The primary goal of the study is to evaluate the safety of the EndoLift Liver Retractor as an internal laparoscopic liver retraction device.
- Conditions
- Minimally Invasive Surgical Procedure, Laparoscopic Gastric Banding, Laparoscopic Roux-en-Y Gastric Bypass, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT02008409
- Testing
- EndoLift Liver Retractor
- Where
- United States
- Sponsor
- Duke University
Bariatric Surgery
Dexlansoprazole Absorption and Marginal Ulceration After Gastric Bypass
In Switzerland, the most commonly performed bariatric procedure is the proximal Roux-en-y gastric Bypass surgery. Since marginal ulceration is a known complication after this Operation, a Proton pump Inhibitor (PPI) prophylaxis…
- Trial name
- NCT04423588
- Testing
- dexlansoprazole serum concentration, upper endoscopy
- Sponsor
- Spital Limmattal Schlieren
Obesity, Cardiac Function
Severe Obesity: Bariatric Surgery vs. Life-Style-Intervention
The purpose of this study is to investigate the effects of weight loss induced by gastric bypass surgery in comparison to a psychotherapy-enhanced lifestyle intervention on cardiopulmonary performance and quality of life in…
- Conditions
- Obesity, Cardiac Function, Quality of Life
- Trial name
- WAS (NCT01352403)
- Testing
- Roux-en-Y gastric bypass, Psychotherapy-enhanced lifestyle intervention
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- University of Wuerzburg
Gastric Bypass Surgery, Obesity
Mechanisms of Diabetes Control After Weight Loss Surgery
Obesity and type 2 diabetes (T2DM) are increasing in the US. One third of patients seeking bariatric surgery have T2DM. Although all surgeries result in significant weight loss and often 'cure' the T2DM, the rapid onset and the…
- Trial name
- NCT00571220
- Testing
- gastric bypass surgery, Diet induced weight loss
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Bariatric Surgery, Obesity
Ovarian Reserve and Bariatric Surgery
The expansion of the obesity epidemic is accompanied with an increase in bariatric procedures, in particular in women of reproductive age.
- Conditions
- Bariatric Surgery, Obesity, Reproductive Health, Fertility
- Trial name
- BARIAOVO (NCT04583150)
- Testing
- Bariatric surgery
- Where
- 14 sites in France
- Volunteers
- 238 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes
Effect of Gastric Bypass on Patients With Type 2 Diabetes and/or Dyslipidemia
This is a retrospective review of patients who have undergone bariatric surgery at VUMC and who have type 2 Diabetes and/or dyslipidemia.
- Trial name
- NCT00879125
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Vanderbilt University
Gastric Cancer
Surgery for Obstructed Gastric Carcinoma
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to…
- Trial name
- NCT07435025
- Testing
- palliative gastric resection, palliative bypass
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Obesity
Analysing Differences in Glycaemic Control Immediately Post Obesity SurgEry (The ADIPOSE Study)
It is well established that bariatric (weightloss) surgery affords considerable improvement in glycaemic control (control of blood sugar), and in many cases may lead to a complete resolution of type 2 diabetes.
- Trial name
- ADIPOSE (NCT01515059)
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Leicester
Bariatric Surgery Candidate, Gastric Bypass
Assessment of Pouch Emptying With MRI After Roux-en-Y Gastric Bypass
A cross-sectional observational study in which pouch emptying rate is measured with MRI in good (TWL>35%) and bad responders (TWL<25%) two years after Laparoscopic Roux-en-Y Gastric Bypass (LRYGB).
- Conditions
- Bariatric Surgery Candidate, Gastric Bypass, Obesity, Morbid, Pouch Emptying
- Trial name
- MRI pouch (NCT06298162)
- Testing
- 2 years after RYGB, no intervention. MRI measurement. Observational.
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Rijnstate Hospital
Obesity, Type 2 Diabetes
Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.
Obesity is a growing epidemic throughout the world and is followed by increasing incidence of type 2 diabetes that accounts for 90-95% of all cases of diabetes.
- Conditions
- Obesity, Type 2 Diabetes, Bariatric Surgery
- Trial name
- CONTROL (NCT01984762)
- Testing
- Roux-en-Y gastric bypass, sleeve gastrectomy
- Where
- Sweden
- Volunteers
- 134 people
- Sponsor
- Göteborg University
Hyperinsulinemic Hypoglycemia, Postprandial Hypoglycemia
Dasiglucagon in the Treatment of Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass
The aim of this study is investigating the effect of a novel glucagon analogue administration in gastric bypass operated individuals, who are reactive hypoglycemic.
- Trial name
- NCT03984370
- Testing
- ZP4207
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Diabetes Mellitus Type 2 in Obese
DMBSS-A Randomized Trial of Different Laparoscopic Gastric Bypass Surgery in Patients With Obesity-related T2DM
The investigators would like to conduct a randomized clinical trial to compare the efficacy of diabetes treatment between different gastric bypass procedures involving type 2 diabetics patients with BMI from 27.5 to 35 kg/m2
- Trial name
- DMBSS (NCT01989988)
- Testing
- LMGB, LRYGB, SADJB
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Gastric Outlet Obstruction
EUS - Guided Balloon-occluded Gastrojejunostomy Bypass
Surgical gastrojejunostomy is the conventional treatment for palliating patients suffering from of inoperable malignant gastric outlet obstruction (GOO).
- Trial name
- NCT03223480
- Testing
- EUS-guided gastrojejunstomy
- Where
- Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong
Obesity and Obesity-related Medical Conditions
Revision Surgery for Suboptimal Weight Loss or Recurrent Weight Gain After Roux-en-Y Gastric Bypass
The majority of those who undergo gastric bypass surgery have a good/sufficient weight loss, averaging 25-30% after 10-20 years (Adams TD NEJM -18).
- Trial name
- REDO (NCT06857578)
- Testing
- Total revision of Roux-en-Y gastric bypass
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Linkoeping University