Clinical trials: Gastric Bypass Surgery
Bariatric Surgery Candidate, Protein Deficiency
Effect of Protein Supplementation on Fat Free Mass Preservation After Bariatric Surgery
This double blind randomized placebo controlled trial investigates the effect of protein supplementation on fat free mass loss in patients who underwent a Roux-en-Y gastric bypass.
- Conditions
- Bariatric Surgery Candidate, Protein Deficiency, Muscle Loss
- Trial name
- PROMISE (NCT05570474)
- Testing
- Protein drink supplementation
- Where
- Netherlands
- Volunteers
- 266 people
- Sponsor
- Maasstad Hospital
Diabetes Mellitus Type 2
Effects on Remission of Type 2 Diabetes Mellitus Following Gastric Bypass Alone vs Gastric Bypass Combined With Truncal Vagotomy
This randomized, triple-blind clinical trial investigates whether adding truncal vagotomy to Roux-en-Y gastric bypass (RYGB) enhances remission of type 2 diabetes mellitus (T2DM) in patients with obesity.
- Trial name
- VagusSx (NCT07278115)
- Testing
- Roux-en-Y Gastric Bypass plus Truncal Vagotomy, Roux-en-Y Gastric Bypass
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University Research Institute for the Study of Genetic & Malignant Disorders in Childhood
Obesity
Roux-en-Y Gastric Bypass and Weight Regain
This study compares eating behaviors, meal size, and the size of the gastric pouch and connection between the gastric pouch and small intestine in patients who had gastric bypass surgery two or more years ago and regained weight…
- Trial name
- NCT02302898
- Testing
- Eating Behavior Evaluation, Measurement of Functional gastric volume, Measurement of gastric pouch and GJ size
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Gastric Bypass Surgery
The Effects of Probiotic Supplementation on the Results of Gastric Bypass Surgery
In this study, patients undergoing the bariatric surgery will be assigned to take either probiotic capsules or placebos from 1 month before surgery to 3 months after the surgery.
- Trial name
- NCT02708589
- Testing
- probiotic
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute
Obesity and Obesity-related Medical Conditions
Bariatric Surgery vs. Semaglutide vs. Tirzepatide
The recent introduction of the new generation of anti-obesity medications (AOMs) will change the future of obesity treatment. These highly effective medications, such as high-dose semaglutide and tirzepatide, are hormone…
- Trial name
- NCT06803888
- Testing
- Bariatric Surgery, Semaglutide, Tirzepatide
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Ali Aminian
Morbid Obesity, Obesity
TSBL-Based Versus BMI-Based Biliopancreatic Limb Length in One-Anastomosis Gastric Bypass
This study compares two surgical techniques used during one-anastomosis gastric bypass (OAGB) surgery for patients with severe obesity.
- Trial name
- TSBL-OAGB (NCT07796503)
- Testing
- TSBL-based biliopancreatic limb length determination, BMI-based biliopancreatic limb length determination
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- National Scientific Center of Surgery named after A.N.Syzganov
Nutritional Deficiency
Nutritional Deficiency After Bariatric Surgeries
comparing micro-nutrient deficiencies in postoperative morbid obese patients who will be undergoing gastric bypass and sleeve gastrectomy with regards to vit B 12, vitamin D,iron studies and calcium .
- Trial name
- NCT04717973
- Testing
- laboratory testing of CBC, serum ferritin, and vitamin B 12
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Adiposity
Study on the Performance of Symmcora® Mid-term Suture Versus Novosyn® Suture in Patients Undergoing Robotic Assisted Gastric Bypass Surgery
The study is designed as a prospective, mono-centric, randomized, patient blinded comparison of unidirectional barbed suture (Symmcora® mid term, UBS) vs. a conventional suture (Novosyn®, CS).
- Trial name
- BARGASTRO (NCT05433688)
- Testing
- Robotic assisted gastric bypass surgery
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Aesculap AG
Type 2 Diabetes
Mechanisms of Diabetes Relapse After Bariatric Surgery
The objective of this study is to investigate the different mechanisms by which Gastric Bypass (GBP), laparoscopic adjustable gastric banding (LAGB) and vertical sleeve gastrectomy (VSG) affect glucose control.
- Trial name
- LAF26 (NCT01516320)
- Testing
- Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Blandine Laferrere
Morbid Obesity
Effect of Bariatric Surgery on Bile Acid Homeostasis
The purpose of this study is to evaluate the effect of bariatric surgery in bile acid homeostasis and its interrelationship with the metabolic changes induced by the surgery.
- Trial name
- NCT02366624
- Where
- Chile
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Contraception
Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery Study
The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery
- Trial name
- NCT06345586
- Testing
- Drospirenone
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chulalongkorn University
Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM)
Comparative Outcomes of One-Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass As Revisional Procedures Following Failed Restrictive Bariatric Surgery
Study Description This prospective, multicenter study aims to compare the outcomes of One-Anastomosis Gastric Bypass (OAGB) and Roux-en-Y Gastric Bypass (RYGB) as revisional procedures for patients experiencing insufficient…
- Conditions
- Obesity, Morbid, Type 2 Diabetes Mellitus (T2DM), Hypertension, Dyslipidemia
- Trial name
- COBRA stady (NCT06794892)
- Where
- Italy
- Volunteers
- 328 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Gastric Bypass After Previous Anti-reflux Surgery
The goal of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional Roux-en-Y gastric bypass (RYGB) after either…
- Trial name
- RYGBafterARS (NCT01041105)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Osteopenia
BP Limb Length of 60cm vs 100cm in Roux-en-Y Gastric Bypass
Patients will be randomized into 2 groups: Group 60: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic limb length of 60cm Group 100: Patients will undergo a Roux-en-Y gastric bypass with a Biliopancreatic…
- Trial name
- NCT04377230
- Testing
- biliopancreatic limb length of 60cm., biliopancreatic limb length of 100cm.
- Volunteers
- 200 people
- Sponsor
- Hospital General Universitario Elche
Obesity, Osteoarthritis
Symptomatic, Biomechanical and Radiographic Outcomes in Knee Osteoarthritis Following Gastric Bypass Surgery
Weight is a risk factor for knee osteoarthritis Knee osteoarthritis is associated with abnormal gait biomechanics Gait biomechanics are evaluated in gastric bypass patients before and after losing 100 pounds.
- Trial name
- NCT00194051
- Testing
- gastric bypass surgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University Hospitals Cleveland Medical Center
Roux-en-Y Gastric Bypass
Changes in Food Preference and Food Cue Responsivity After Bariatric Surgery
It has been suggested that obese people are more sensitive to sensory and rewarding effects of food, aspects that mediate food preferences and intake.
- Trial name
- Verrukkelijk (NCT02068001)
- Testing
- Roux-en-Y Gastric Bypass
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Wageningen University
Small Gestational Age (SGA), Hypoglycemia After Gastric Bypass
Glycemic Variability During Pregnancy After Bariatric Surgery
Pregnancies after Metabolic and Bariatric Surgery (MBS) are linked to increased incidence of small-for-gestational-age (SGA) neonates.
- Conditions
- Small Gestational Age (SGA), Hypoglycemia After Gastric Bypass, Glycemic Variability
- Trial name
- NCT07731165
- Testing
- Intermittently Scanned Continuous Glucose Monitoring (isCGM)
- Where
- Portugal
- Volunteers
- 47 people
- Sponsor
- Centro Hospitalar Universitário de Santo António
Severe Obesity, Bariatric Surgery
Study on Impact of Lifestyle Change and Weight Loss Before Bariatric Surgery
The purpose of the trial is to determine whether a preoperative lifestyle intervention (targeting diet, exercise, and preparation for surgery) will favorably impact obesity-related parameters prior to bariatric surgery and…
- Trial name
- PREP (NCT00623792)
- Testing
- Preoperative lifestyle Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duquesne University
Obesity, Bariatric Surgery
Effects of Bariatric Surgery on Insulin
This study, conducted at the NIH Clinical Research Unit (CRU) at the Phoenix Indian Medical Center, will compare the effects of two methods of bariatric surgery, the adjustable BAND and Roux-en-Y gastric bypass, on insulin.
- Conditions
- Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss
- Trial name
- NCT00535600
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)