Clinical trials: Gastric Cancer, completed
Gastrointestinal Stromal Tumors
Laparoscopic Resection of Large Gastric Stromal Tumors
Despite laparoscopic surgical treatment has not been recommended in patients with gastric gastrointestinal stromal tumors (GIST) larger than 5 centimeter, but it continues to evolve rapidly to overcome the boundaries.
- Trial name
- NCT02662478
- Testing
- Laparoscopic Surgery
- Volunteers
- 23 people
- Sponsor
- Medical Park Gaziantep Hospital
Islet Cell Adenoma, Zollinger Ellison Syndrome
Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer
This study will examine the safety and effectiveness of interferon-a and octreotide for the treatment of Zollinger-Ellison syndrome (gastrinoma) and advanced non-B islet cell cancer.
- Trial name
- NCT00001228
- Testing
- Interferon
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gastric Subepithelial Tumor
Novel Endoscopic Resection of Upper Gastrointestinal Subepithelial Tumors Originating From the Muscularis Propria
Endoscopic submucosal tumor resection using biopsy forceps was performed for 11 consecutive patients who had clinical indications for lesion removal.
- Trial name
- NCT03037034
- Testing
- Forcep
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Korea University Anam Hospital
Advanced Gastric Cancer
Phase II Study of Epirubicin, Cisplatin and Capecitabine (ECX) Versus Cisplatin and Capecitabine (CX) for Advanced Gastric Cancer (AGC)
Recently, 3-drug (ECX) and 2-drug (CX) combination chemotherapy involving capecitabine showed promising results in randomized clinical trials for advanced gastric cancer (AGC).
- Trial name
- NCT00743964
- Testing
- Epirubicin, Cisplatin, capecitabine
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Gastric Adenocarcinoma
Different Cycles of Neoadjuvant PD-1 Blockades + Chemotherapy for Advanced Gastric Cancer
The goal of this observational study is to analyze the impact of different durations of neoadjuvant PD-1 inhibitor combined with chemotherapy on tumor regression and safety in patients with advanced gastric cancer.
- Trial name
- NCT06798376
- Testing
- 2-4 cycles of neoadjuvant PD-1 Inhibitors combined with chemotherapy, 5-8 cycles of neoadjuvant PD-1 Inhibitors combined with chemotherapy, Gastrectomy
- Where
- China
- Volunteers
- 409 people
- Sponsor
- Chinese PLA General Hospital
Esophageal Neoplasms, Stomach Neoplasms
Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer
The aim of this study is to identify biomarkers predicting response or resistance factors of a targeted therapy with trastuzumab in advanced gastric cancer.
- Trial name
- VARIANZ (NCT02305043)
- Testing
- non-interventional
- Where
- Germany
- Volunteers
- 549 people
- Sponsor
- University of Leipzig
Resected Advanced Gastric Cancer
Adjuvant Chemotherapy With Docetaxel, Capecitabine and Cisplatin in Patients With Advanced Gastric Cancer: Adjuvant DXP
Despite the improvement of surgical resection as primary curative treatment for gastric cancer, more than 70% of patients with stage IIIB and IV disease undergoing radical primary tumor resection relapse and die within 5 years.
- Trial name
- NCT00976976
- Testing
- docetaxel, capecitabine, cisplatin
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Asan Medical Center
Stage II-III Gastric Cancer
A Validation Study of Relationships Among Genomic Gene Expression Profile, Prognosis and Prediction of Adjuvant Chemotherapy Benefit With Capecitabine and Oxaliplatin in Gastric Cancer Stage II and III (6th AJCC) Patients After D2 Surgery (CLASSIC)
The purpose of this study is to validate a pre-defined single-patient classifier algorithm for predicting prognosis and benefit from adjuvant chemotherapy for patients who underwent D2 gastrectomy for stage II and III gastric…
- Trial name
- NCT03403296
- Testing
- nProfiler I Stomach Cancer Assay Kit
- Where
- South Korea
- Volunteers
- 640 people
- Sponsor
- Yonsei University
Adenocarcinoma, Adenocystic Carcinoma
The Registry of Oncology Outcomes Associated With Testing and Treatment
This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation.
- Conditions
- Adenocarcinoma, Adenocystic Carcinoma, Anal Cancer, Appendix Cancer
- Trial name
- ROOT (NCT04028479)
- Testing
- Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Taproot Health
Stomach Neoplasms
Enhanced Magnifying Endoscopy for Diagnosis of Early Gastric Cancer
When performing screening endoscopy, small focal gastric lesions are frequently encountered. Novel techniques in endoscopy, such as magnifying endoscopy (ME) with narrow-band imaging (NBI) and chromoendoscopy with acetic…
- Trial name
- NCT01617876
- Where
- China
- Volunteers
- 282 people
- Sponsor
- Peking Union Medical College Hospital
Gastric Cancer Metastatic to Lung, Lung Cancer
Study for Patients With Lung Metastatic Advanced Gastric Cancer and NSCLC Treated With Apatinib
The primary end point was progression-free survival (PFS), secondary end points included duration of locoregional control (LRC), overall survival (OS), quality of life and safety.
- Trial name
- NCT03629691
- Testing
- lung cavitation
- Volunteers
- 187 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Stomach Neoplasms
S-1 Plus Oxaliplatin Compared With Fluorouracil, Leucovorin Calcium Plus Oxaliplatin as Perioperative Chemotherapy for Advanced Gastric Carcinoma
This is a randomized multicenter controlled study of oxaliplatin, leucovorin calcium , plus 5-fluorouracil (FOLFOX) compared with S-1 plus oxaliplatin (SOX) as perioperative chemotherapy for advanced gastric cancer.
- Trial name
- Focus (NCT01364376)
- Testing
- S-1; Oxaliplatin; 5-Fu; Leucovorin Calcium
- Where
- 8 sites in China
- Volunteers
- 583 people
- Sponsor
- Zhejiang University
Colorectal Cancer, Gastric Cancer
Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy
The study is testing an intervention of an investigator-developed chemotherapy dose adjustment algorithm. The primary objective of this study is to evaluate the effectiveness of the chemotherapy dose adjustment algorithm for…
- Conditions
- Colorectal Cancer, Gastric Cancer, Esophageal Cancer, Ampullary Cancer
- Trial name
- NCT04526886
- Testing
- Algorithm for cytopenia-related delay and dose-reduction of mFOLFOX chemotherapy
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Gastric Cancer
Chemotherapy Options for the First Line Chemotherapy in Elderly Patient With Advanced Gastric Cancer
The investigators compare the overall survival between combination chemotherapy and monochemotherapy as a first-line chemotherapy in elderly patients with metastatic or recurrent gastric cancer.
- Trial name
- NCT02114359
- Testing
- Capecitabine/cisplatin, S-1/cisplatin, Capecitabine/oxaliplatin
- Where
- 14 sites in South Korea
- Volunteers
- 111 people
- Sponsor
- Seoul National University Hospital
Gastric Cancer
da Vinci SP Robotic Gastrectomy
Laparoscopic surgery revolutionized the surgical treatment of gastric cancer saving large incsion and associated pain. Robotic surgical system was introduced to enhance the minimally invasive surgery using articulating robotic…
- Trial name
- NCT05051670
- Testing
- da vinc SP gastrectomy
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Yonsei University
Stomach Neoplasms
Compliance to ERAS After Gastric Surgery
The purpose of this study is to prospectively evaluate the overall compliance to the enhanced recovery after surgery (ERAS) program in patients undergoing gastric cancer surgery.
- Trial name
- ERAS (NCT01653496)
- Testing
- Enhanced recovery after surgery
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Chonnam National University Hospital
Solid Tumor
A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination With Chemotherapy or Toripalimab in Advanced Solid Tumors
A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination with Chemotherapy or Toripalimab in Advanced Solid Tumors
- Trial name
- NCT05173142
- Testing
- HMPL-453, gemcitabine and cisplatin, toripalimab
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Hutchison Medipharma Limited
Gastric Cancer
XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC)
Our study aims to compare 4 months versus 6 months of adjuvant capecitabine plus oxaliplatin after D2 gastrectomy in patients with gastric cancer.
- Trial name
- NCT03399110
- Testing
- Oxaliplatin, Capecitabine
- Where
- 10 sites in China
- Volunteers
- 1,024 people
- Sponsor
- Fudan University
Gastric Cancer
Combination Chemotherapy and Surgery in Treating Patients With Locally Advanced Stomach Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery may kill more tumor cells.
- Trial name
- NCT00005060
- Testing
- Taxotere-Cisplatin-5FU, Immediate surgery
- Where
- 3 sites in Italy, Switzerland
- Volunteers
- 240 people
- Sponsor
- Swiss Cancer Institute
Adenocarcinoma, Gastric, Neoplasm, Breast
DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein
HER2-positive cancer is a cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 promotes the growth of certain cancer cells.
- Trial name
- NCT03368196
- Testing
- DS-8201a
- Where
- 2 sites in Taiwan
- Volunteers
- 12 people
- Sponsor
- Daiichi Sankyo Taiwan Ltd., a Daiichi Sankyo Company
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