Clinical trials: Gastric Carcinoma
Gastritis, Dyspepsia
Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of high-dose esomeprazole and amoxicillin dual therapy(esomeprazole and amoxicillin) versus bismuth-containing quadruple Therapy(bismuth，esomeprazole，tetracycline and…
- Conditions
- Gastritis, Dyspepsia, Helicobacter Pylori Infection, Gastric Cancer
- Trial name
- NCT04678492
- Testing
- Esomeprazole, Amoxicillin, Bismuth
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Cancer
Randomized Controlled Study of Postoperative Adjuvant Therapy for Gastric Cancer Using TS-1 or TS-1+PSK
A randomized controlled study is conducted on patients with resected gastric cancer assigned to postoperative adjuvant therapy of TS-1 alone or PSK combined with TS-1, with the objective to examine or validate the outcome, QOL…
- Trial name
- NCT00216034
- Testing
- Tegafur-gimeracil-oteracil potassium (TS-1), Krestin (PSK)
- Where
- 42 sites in Japan
- Volunteers
- 255 people
- Sponsor
- Hokuriku-Kinki Immunochemotherapy Study Group
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction
Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA
ARTemIS-Eso is a phase I-II, three-level, open-label trial with a dose-expansion cohort at recommended schedule in both esophageal cancer histological groups (squamous cell carcinoma and adenocarcinoma) of RCT and ImT…
- Conditions
- Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Squamous Cell Carcinoma of the Esophagus
- Trial name
- ARTEMIS-Eso (NCT03307941)
- Testing
- Monalizumab, Oxaliplatin, 5-Fluorouracil
- Where
- Belgium
- Sponsor
- Jules Bordet Institute
HER2-positive Gastric Cancer
Study of HLX10, Trastuzumab and Chemotherapy in First-line Treatment of HER2-positive Recurrent/Metastatic Gastric Cancer
Investigators assessed the effectiveness of HLX10, Trastuzumab and Chemotherapy in First-line Treatment of HER2-positive Recurrent/Metastatic Gastric Cancer
- Trial name
- NCT05311189
- Testing
- HLX10, Trastuzumab and Chemotherapy
- Volunteers
- 40 people
- Sponsor
- Shanghai Zhongshan Hospital
Lung Cancer, Gastro-Intestinal Cancer
Whey Protein Supplement in Combination With Physical Exercise and Nutrition Program
This study evaluates physical performance in cancer outpatients during a multimodal therapy. Half of the patients will receive physical exercise und nutrition program in combination with a specially formulated whey protein…
- Conditions
- Lung Cancer, Gastro-Intestinal Cancer, Breast Cancer, Prostate Cancer
- Trial name
- NCT02585362
- Testing
- physical exercise, nutrition counseling, whey protein supplement
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Kantonsspital Winterthur KSW
Colorectal Neoplasms, Stomach Neoplasms
Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response
- Conditions
- Colorectal Neoplasms, Stomach Neoplasms, Pancreatic Neoplasms, Breast Neoplasms
- Trial name
- NCT00419627
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Hillel Yaffe Medical Center
Gastric Cancer, MicroRNAs
MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection
The goal of this observational study is to compare specific microRNA levels from the plasma of gastric cancer patients and healthy volunteers to see if there is an upregulated expression in gastric cancer patients.
- Trial name
- NCT05901376
- Testing
- MicroRNA
- Where
- Thailand
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- King Chulalongkorn Memorial Hospital
Pancreatic Cancer, Colo-rectal Cancer
Prehabilitation in High-risk Oncologic Surgery
The goal of this clinical study is to learn whether a prehabilitation program can improve recovery after major abdominal surgery in adults with cancer who are receiving treatment before surgery.
- Conditions
- Pancreatic Cancer, Colo-rectal Cancer, Gastric Cancer, Esophageal Cancer
- Trial name
- NCT07638410
- Testing
- Multidisciplinary Prehabilitation Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Fox Chase Cancer Center
Gastric Cancer
Perianastomotic Drain After Gastrectomy (DRAG)
Gastric cancer ranks as the fifth most common and fifth most lethal cancer globally. For patients with AJCC stages IB to IIIC, representing the majority of cases, the current gold standard of surgical treatment involves total…
- Trial name
- DRAG (NCT04288661)
- Testing
- No drain placement
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- THEODOROU DIMITRIOS
Metastatic Gastric Adenocarcinoma, Metastatic Gastroesophageal Junction Adenocarcinoma
Apatinib Plus Camrelizumab Combined With Docetaxel and S1 in First-line Treatment for Metastatic Gastric Cancer
The purpose of this study is to evaluate the efficacy and safety of Apatinib plus Camrelizumab combined with docetaxel and S-1 as the first-line treatment of metastatic adenocarcinoma of gastric and gastroesophageal junction.
- Trial name
- NCT04781686
- Testing
- Camrelizumab, Apatinib Mesylate, S1
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Zhou Fuxiang
Gastric Cancer
Combination Chemotherapy and Surgery in Treating Patients With Locally Advanced Stomach Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery may kill more tumor cells.
- Trial name
- NCT00005060
- Testing
- Taxotere-Cisplatin-5FU, Immediate surgery
- Where
- 3 sites in Italy, Switzerland
- Volunteers
- 240 people
- Sponsor
- Swiss Cancer Institute
Gastric Adenocarcinoma, Gastric Squamous Cell Carcinoma
Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer
This phase II trial studies how well pembrolizumab and palliative radiation therapy works in treating patients with esophagus, stomach, or gastroesophageal junction cancer that has spread to other parts of the body.
- Conditions
- Gastric Adenocarcinoma, Gastric Squamous Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma, Metastatic Malignant Neoplasm in the Stomach
- Trial name
- NCT02830594
- Testing
- External Beam Radiation Therapy, Laboratory Biomarker Analysis, Pembrolizumab
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- City of Hope Medical Center
Gastric Cancer
The Efficacy and Safety of Benmelstobart for GC/EGC
The goal of this clinical trial is to evaluate the major pathological response (MPR) rate of locally advanced gastric cancer / gastroesophageal junction cancer treated with bemosumab combined with antiangiogenic drugs and…
- Trial name
- EASOBFGE (NCT06603974)
- Testing
- surgery, Benmelstobart, tegafur
- Volunteers
- 48 people
- Sponsor
- Xijing Hospital
Gastric Cancer, Gastric (Stomach) Cancer
Gastric Cancer Endoscopic Screening in an Intermediate-risk Country - ROGCAS, a Dual-centre Pilot Program
Endoscopic screening of gastric cancer combined with screening colonoscopy
- Conditions
- Gastric Cancer, Gastric (Stomach) Cancer, Atrophic Gastritis, Intestinal Metaplasia of Gastric Mucosa
- Trial name
- ROGCAS (NCT06316882)
- Testing
- Screening endoscopy
- Where
- Portugal
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Unidade Local De Saúde Do Norte Alentejano
Stomach Neoplasms
Exploratory Study of Drug Sensitivity Prediction Software (IRCR-DReSS) With Patient-derived Tumor Cells of Metastatic Gastric Cancer
1. Metastatic gastric cancer patients who failed standard treatment will be enrolled in this study. 2. After consent form, patient-derived cancer cell will be collected and tested with 3 kinds of drugs (sunitinib, gefitinib…
- Trial name
- NCT03170180
- Testing
- Sunitinib, Gefitinib, Imatinib
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Samsung Medical Center
Stomach Neoplasms, Stomach Cancer
Prospective Evaluation and Molecular Profiling in People With Gastric Tumors
Background: Certain stomach cancers are rare, but they have high mortality rates. Researchers want to learn more about gastric (stomach) tumors.
- Trial name
- NCT03027427
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Cancer
Postoperative Sequence Chemoradiotherapy Compared With Chemotherapy Alone for Advanced Gastric Cancer
Gastric cancer is one of the most prevalent malignancies in China; the survival rate remains poor despite potentially curative resections.
- Trial name
- NCT01197118
- Testing
- sequence chemoradiotherapy, chemotherapy alone following radical resection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huazhong University of Science and Technology
Esophageal Cancer, Gastric Cancer
Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol)
Esophageal cancer and cancers of the gastroesophageal junction (GEJ) are among the most common malignancies worldwide. The outcome for these patients remains very poor.
- Conditions
- Esophageal Cancer, Gastric Cancer, Oligometastatic Disease
- Trial name
- TORO (NCT06668454)
- Testing
- Surgical resection followed by preoperative chemoimmunotherapy for oligometastatic esophagogastric cancer
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- University Health Network, Toronto
Cancer, Metastatic, Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and…
- Conditions
- Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
- Trial name
- NCT03452774
- Testing
- Clinical Trial Matching
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 50,000 people
- Sponsor
- Massive Bio, Inc.