Clinical trials: Gastric Content
Healthy Volunteer
Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor
An open label, multicentre, randomised, 2-cohort, sequential and crossover study to assess the relative oral bioavailability of MT-7117 higher content tablets versus MT-7117 lower content tablets and the pharmacokinetics of…
- Trial name
- MT-7117 BA DDI (NCT03688022)
- Testing
- MT-7117, PPI, Acidic beverage
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma America, Inc.
Gastric Emptying, Preoperative Care
Incidence of Stomach Fullness and Associated Factors in Elective Surgical Patients
The aim of this prospective, observational study is to evaluate the incidence of residual gastric content in elective surgical patients who adhered to preoperative fasting guidelines and to investigate associated patient-related…
- Conditions
- Gastric Emptying, Preoperative Care, Preoperative Fasting, Elective Surgical Procedures
- Trial name
- NCT06606782
- Where
- Turkey (Türkiye)
- Volunteers
- 404 people
- Sponsor
- Recep Tayyip Erdogan University
Fasting
Gastric Emptying Time After Turkish Breakfast
DETERMINING GASTRIC EMPTYING TIME IN ELDERLY USING ULTRASOUND ASSOCIATED WITH PREOPERATIVE FASTING TIME Background: Gastric contents aspiration is the most crucial complication of general anaesthesia.
- Trial name
- NCT04789785
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Diabetes Mellitus, Type 2, Overweight
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal.
- Conditions
- Diabetes Mellitus, Type 2, Overweight, Obesity
- Trial name
- NCT07299084
- Testing
- Tirzepatide
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Eli Lilly and Company
Surgery
Gastric Ultrasound
The primary objective of this study is to evaluate gastric volume and contents as well as gall bladder size in patients scheduled for routine, urgent, and emergency surgery.
- Trial name
- NCT04127331
- Testing
- Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alok Moharir
Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of Dulaglutide (LY2189265) affect the amount of food and drink that stays in your stomach after a meal.
- Trial name
- GBGT (NCT07313813)
- Testing
- Dulaglutide
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Eli Lilly and Company
Rapid Sequence Induction
Classic and Modified Rapid Sequence Induction for Prevention of Gastric Content Regurgitation
Induction of anesthesia induces a loss of protective upper airway reflexes and is associated with gastric content regurgitation.
- Trial name
- NCT04312425
- Testing
- Modified rapid sequence induction, Classic rapid sequence induction
- Where
- China
- Volunteers
- 8,601 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diabetes, Gastric Content Aspiration
Effects of GLP-1 Agonists on Gastric Volume
This study will enroll patients ages 18 and over who have a diagnosis of diabetes, are undergoing an elective surgery under general anesthesia and 1) are taking a GLP-1 receptor agonist medication, or 2) not taking a GLP-1…
- Conditions
- Diabetes, Gastric Content Aspiration, Glucagon-like Peptide 1, GLP-1
- Trial name
- NCT05854979
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Medical University of South Carolina
Upper GI Bleeding, Point of Care Ultrasound
Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy
Emerging studies have evaluated POCUS (Point of Care Ultrasound) for assessing of gastric content prior to anesthesia to reduce the risk of aspiration and demonstrated that POCUS can accurately identify presence of gastric food…
- Conditions
- Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content
- Trial name
- NCT05763745
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Respiratory Aspiration of Gastric Content
AuraGainTM and I-Gel® Laryngeal Masks in General Anesthesia for Laparoscopic Cholecystectomy
The standard procedure used for airway control in general anesthesia for LC (laparoscopic cholecystectomy) is endotracheal intubation (EI).
- Trial name
- AILMALC (NCT02925598)
- Testing
- I-gel LMA insertion, AuraGain LMA insertion, ETT insertion
- Volunteers
- 114 people
- Sponsor
- Adiyaman University Research Hospital
Variation of the Antral Area After Cigarettes Smoking or Not
Cigarette and Gastric Contents
The aims of this cross over prospective study are to demonstrate that smoking two cigarettes do not change the gastric contents and volume in fasting volunteers.
- Trial name
- NCT02080598
- Testing
- 2 cigarettes in 15 minutes
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lionel Bouvet
Suxamethonium Sensitivity, Aspiration of Gastric Contents Into Respiratory Tract, Part Unspecified
Comparison on Succinylcholine Onset Time Assessed by Train of Four Stimulation Versus Clinical Judgment During Rapid Sequence Induction of Anesthesia
Succinylcholine is a myorelaxant agent often used during rapid sequence induction for patients who need to undergo general anesthesia but who are at risk of pulmonary aspiration of gastric content.
- Trial name
- CELOTOF (NCT03415607)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Caen
Fasting, Hunger
Patient Satiety as an Indicator of Stomach Contents and Fluid Volume
This research proposal aims to investigate the correlation between a) the hunger feeling as measured by a ten point scale and b) total gastric fluid volumes and content as measured with gastric PoCUS in fasted, healthy subjects >…
- Trial name
- NCT04884373
- Testing
- Gastric ultrasound
- Where
- Belgium
- Volunteers
- 501 people
- Sponsor
- Imeldaziekenhuis
Pneumonia, Aspiration, Gastric Content
Point-of-care Gastric Ultrasound for Fracture Surgery
Although there are fasting guidelines offered by the American Society of Anesthesiology (ASA) for managing preoperative patient assessment, some patients may need to be more cautious about the risk of aspiration.
- Conditions
- Pneumonia, Aspiration, Gastric Content, Fractures, Bone
- Trial name
- NCT05728242
- Testing
- Gastric ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Haseki Training and Research Hospital
Gastric Emptying, Diabetes
Gastric Ultrasound in Diabetic Patients
The American Society of Anesthesiologists (ASA) does not specify a fasting period for patients with certain comorbidities, such as diabetes, for elective surgery, and does not make a separate recommendation for surgery.
- Conditions
- Gastric Emptying, Diabetes, Ultrasound
- Trial name
- NCT06195488
- Testing
- Gastric ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Gastroparesis
Ultrasound Assessment of Gastric Contents in Fasted Patient Undergoing Cholecystectomy
Investigators assess the gastric contents by ultrasonography in fasted patients undergoing cholecystectomy.
- Trial name
- NCT03259841
- Testing
- Ultrasound assessment of gastric contet
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- SMG-SNU Boramae Medical Center
Obesity, Overweight and/or Obesity
A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity
This study looks at how a study medicine called PF-08653944 affects how quickly the stomach empties food after eating. It is being done in adults who are overweight or have obesity.
- Conditions
- Obesity, Overweight and/or Obesity, Overweight, Drug Interaction
- Trial name
- NCT07508241
- Testing
- PF-08653944, Acetaminophen
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Residual Gastric Contents, Delayed Gastric Emptying
GLP-1 RA Cessation and Gastric Ultrasound Findings
This prospective observational study will evaluate the association between the time interval since the last dose of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and residual gastric contents before elective surgery.
- Trial name
- NCT07623148
- Testing
- GLP-1 RA Cessation Interval
- Where
- South Korea
- Volunteers
- 186 people
- Sponsor
- Wonkwang University Hospital
Pulmonary Aspiration, Gastric Content Aspiration
Ultrasound Assessment of Gastric Volume in Diabetic Versus Non-Diabetic Term Pregnant Women Undergoing Cesarean Section
The aim of the work to compare estimated gastric volumes through ultrasound in fasting diabetic and non-diabetic pregnant women scheduled for caesarean section.
- Trial name
- NCT06621706
- Testing
- Gastric ultrasonography
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
Fasting, Pediatric ALL
Effect of NPO Time and Type of Food Intake on Preoperative Residual Gastric Content and pH
According to normal physiology, the longer fasting period allows food particles to pass stomach through small intestines to minimize intragastric content.
- Trial name
- NCT03448991
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital