Clinical trials: Gastric Diseases
Surgical Site Infections, Gastric Cancer
Povidone-iodine and the Normal Saline Cleaning the Incision for the SSIs
Surgical site infections (SSIs) is one of the most common complications of upper abdominal surgery. Previous studies found that type of surgical incision, emergency operation or not, surgical duration, age of patient, body mass…
- Conditions
- Surgical Site Infections, Gastric Cancer, Dehiscence of Laparotomy Wound
- Trial name
- NCT02436395
- Testing
- Group A (povidone-iodine wash the surgical incision), Group B (normal saline wash the surgical incision)
- Where
- China
- Volunteers
- 340 people
- Sponsor
- West China Hospital
GastroEsophageal Cancer, Gastric Cancer
Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer
The purpose of the study is to test the effects, both good and bad, of the research study drug Neratinib in combination with Trastuzumab, Pembrolizumab and FOLFOX chemotherapy.
- Trial name
- NCT06109467
- Testing
- Neratinib, Trastuzumab, Oxaliplatin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Morbid Obesity, Bariatric Surgery
LAGB Versus VBG: 7-Year Results
The study aims to investigate the long term results of a randomized clinical single-centre trial comparing two standard operative techniques in bariatric surgery; laparoscopic adjustable gastric banding and vertical banded…
- Conditions
- Morbid Obesity, Bariatric Surgery, Vertical Banded Gastroplasty, Laparoscopic Adjustable Gastric Banding
- Trial name
- NCT00840736
- Testing
- Laparoscopic adjustable gastric banding, vertical banded gastroplasty
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center
Solid Tumor, Hepatocellular Carcinoma
Vorolanib (X-82) Combined With Checkpoint Inhibitors in Patients With Solid Tumors
The investigators hypothesize that vorolanib in combination with checkpoint inhibitors (pembrolizumab for gastric/gastroesophageal (GE) junction cancers and nivolumab for hepatocellular carcinoma (HCC)) may improve immunotherapy…
- Conditions
- Solid Tumor, Hepatocellular Carcinoma, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT03511222
- Testing
- Vorolanib, Nivolumab, Pembrolizumab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Neoplasm of Stomach
Effect of a Self-designed MET Exercise Intervention on Cancer-related Fatigue in Patients With Gastric Cancer
To investigate the effect of using Self-arranged Metabolic Equivalent Exercises on cancer-related fatigue in gastric cancer patients.
- Trial name
- SMEE (NCT05401045)
- Testing
- Met exercises
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Ruijin Hospital
Gastric Cancer
Study on the Effectiveness of Gastroscope Operation Quality Control Based on Artificial Intelligence Technology
This study aims to construct a real-time quality monitoring system based on artificial intelligence technology.
- Trial name
- NCT04384575
- Testing
- blind spots
- Where
- China
- Volunteers
- 1,570 people, healthy volunteers welcome
- Sponsor
- Peking University
Stomach Neoplasms, Gastric Cancer (Diagnosis)
Lymph Node Metastasis Pattern After Neoadjuvant Chemoimmunotherapy in LAGC
The purpose of this observational study is to learn how stomach cancer that has spread to nearby lymph nodes responds to standard chemotherapy combined with immunotherapy given before surgery.
- Conditions
- Stomach Neoplasms, Gastric Cancer (Diagnosis), Gastric Adenocarcinoma
- Trial name
- NCT07899775
- Testing
- Neoadjuvant SOX chemotherapy combined with PD-1 inhibitor
- Volunteers
- 103 people
- Sponsor
- Hainan General Hospital
Duodenal Ulcer
Helicobacter Pylori Eradication Treatment in Patients With Duodenal Ulcers
The Study purpose is to evaluate Helicobacter pylori susceptibility to Clarithromycin and to estimate eradication and healing rates of duodenal ulcer routine eradication therapy at the end of treatment and 52 weeks from the…
- Trial name
- NCT01199536
- Where
- Russia
- Volunteers
- 59 people
- Sponsor
- AstraZeneca
Peptic Ulcer, Helicobacter Pylori Infection
Clarithromycin Resistant Tailored Therapy
1. Back ground Antibiotics resistance of Helicobacter pylori, especially to clarithromycin is one of the main causes of failure of eradication.
- Trial name
- NCT01453036
- Testing
- 23S rRNA point mutation test of Helicobacter pylori, UBT test & Gastroenterology with biopsy c silver stain
- Where
- South Korea
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Jin Il Kim
Gastric Cancer, Esophageal Neoplasms
Study of Irinotecan and Docetaxel in Patients With Metastatic or Unresectable Gastric or Gastroesophageal Junction Adenocarcinoma
This study is for people with advanced gastric or gastroesophageal cancer. This study is being done to find out how long it takes tumors to grow after receiving treatment with the drugs irinotecan (also known as CPT-11) and…
- Trial name
- NCT00183872
- Testing
- irinotecan, docetaxel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Obesity, Type 2 Diabetes
Magnetic Gastro-Ileal or Gastro-Jejunal Diversion Study ("MGI/MGJ Study")
The purpose of this clinical research study is to evaluate the feasibility of the GT Metabolic Solutions Magnet System, GJ Biofragmentable ("MagGJ System") for creation of a side-to-side anastomosis for gastro-ileal or…
- Trial name
- NCT06073457
- Testing
- MagGJ System
- Where
- 4 sites in Canada, Chile and 2 more
- Volunteers
- 35 people
- Sponsor
- GT Metabolic Solutions, Inc.
Gastric Cancer, Adenocarcinoma of Esophagogastric Junction
TQB2450 Plus Anlotinib Combined With Chemotherapy in the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma
This is a prospective one arm phase II clinical study to evaluate the efficacy and safety of TQB2450 (PD-L1 inhibitor), anlotinib combined with oxaliplatin and capecitabine in patients with unresectable locally advanced…
- Trial name
- NCT04891900
- Testing
- TQB2450/Anlotinib hydrochloride/Oxaliplatin/Capecitabine
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Henan Cancer Hospital
Chronic Obstructive Pulmonary Disease, Bronchiectasis
The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease
Gastric reflux into the oesophagus may further lung damage in respiratory disease. The proportion of adults with chronic lung disease and gastric reflux is unknown.
- Trial name
- NCT00697177
- Where
- Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Functional Gastrointestinal Disorders (FGIDs), Cyclic Vomiting Syndrome
Autonomic Reactivity and Personalized Neurostimulation
Disorders of gut-brain interaction (DGBI) affect up to 25% of U.S. children. Patients often suffer from disabling, multisystem comorbidities that suggest a common root (sleep disturbances, fatigue, anxiety, etc).
- Conditions
- Functional Gastrointestinal Disorders (FGIDs), Cyclic Vomiting Syndrome, Functional Dyspepsia, Dysautonomia
- Trial name
- NCT06863207
- Testing
- Percutaneous electrical nerve field stimulation, Hypnotherapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma
Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
This phase II trial tests how well olanzapine works in managing cancer cachexia in patients experiencing esophagogastric, hepatopancreaticobiliary, colorectal, or lung cancer that may have spread from where it first started to…
- Conditions
- Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma, Advanced Esophageal Carcinoma, Metastatic Esophageal Carcinoma
- Trial name
- NCT05705492
- Testing
- Olanzapine, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- OHSU Knight Cancer Institute
Carcinoma, Glioblastoma
MRinRT: Swansea University and SWWCC Collaboration Study.
The aim of this study is to learn whether using MRI (magnetic resonance imaging) scans to plan radiotherapy is better than using CT (computed tomography) scans alone.
- Conditions
- Carcinoma, Glioblastoma, Radiotherapy, MRI
- Trial name
- MRinRT (NCT07365124)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
Gastric Cancer
A Comparison Between D1 and D2 Lymphadenectomy in Gastric Cancer : A Prospective Randomized Controlled Trial
Gastric cancer remains the second most common cancer worldwide.Although the prognosis is poor for majority of patients , long term survival is achievable in patients in whom surgical resection is possible.
- Trial name
- NCT00447746
- Testing
- D1 or D2 lymphadenectomy for gastric cancer patients
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Tata Memorial Hospital
Stomach Cancer
The Effect of Deep Neuromuscular Block on the Perioperative Stress Response Reduction and Postoperative Recovery Enhancement in Robot-assisted Stomach Cancer Surgery
Stress reactions caused by surgical stimuli can cause sympathetic nervous system activation and increased stress hormones, such as catecholamines, inflammatory cytokines, and pituitary hormones, and insulin resistance.
- Trial name
- NCT03937440
- Testing
- Deep neuromuscular block with 'rocunium®', Moderate neuromuscular block with 'rocunium®'
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yonsei University
Helicobacter Pylori Infection, Premalignant Lesion
Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion
The aim of this study is to evaluate the impact of artificial intelligence (AI) assistance during routine upper endoscopy on gastric cancer-specific mortality.
- Trial name
- NCT05762991
- Testing
- Routine endoscopy with artificial intelligence-assisted interpretation
- Where
- Taiwan
- Volunteers
- 6,000 people
- Sponsor
- National Taiwan University Hospital
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