Clinical trials: Gastric Retention
Gastric Retention
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
Glucagon-like peptide-1 agonists (GLP-1RA) are a family of medications used for diabetes and weight loss. One of their effect is to slow down stomach emptying.
- Trial name
- RESIDUAL (NCT06500143)
- Testing
- Gastric ultrasound
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gastric Retention
Impact of Neuropathy on the Risk of Semaglutide-Induced Gastric Retention
A prospective, single-center, observational study to compare the risk of gastric retention between the exposure group (with neuropathy) and non-exposure group (without neuropathy) in diabetic patients receiving uninterrupted…
- Trial name
- NCT07156591
- Testing
- Esophagogastroduodenoscopy
- Where
- China
- Volunteers
- 460 people
- Sponsor
- Fudan University
Gastric Retention
Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric Retention
A retrospective observational study to explore the impact of discontinuing GLP-1 receptor agonists for two weeks prior to upper endoscopy on the risk of gastric retention
- Trial name
- NCT07276763
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 16,509 people
- Sponsor
- Fudan University
Gastric Retention
GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound
This study will enroll patients 18 years and older who are taking a GLP-1/GIP medication and 1) are scheduled for elective surgery and meet ASA fasting guidelines (nothing by mouth for at least 8 hours prior), or 2) scheduled…
- Trial name
- NCT07251803
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Gastric Retention
the Effect of Abdominal Massage on the Gastric Residual Volume.
The goals of this randomized controlled trial are: 1. To determine the mean gastric residual volume in ICU admitted adult patients before and after intervention. 2.
- Trial name
- NCT06062381
- Testing
- Abdominal Massage
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Health Sciences Lahore
Gastric Retention, Healthy
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults
To assess how long extended release prototype capsule formulations stay in the stomach as determined by magnetic resonance imaging (MRI).
- Trial name
- NCT03718390
- Testing
- Formulation A, Formulation B, Formulation C
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Gastroparesis, Diabetes
Effect of Tegaserod on Gastric Emptying in Patients With Diabetic Gastroparesis
This study will assess gastric emptying in patients with symptoms of diabetic gastroparesis treated with tegaserod over 2 weeks.
- Trial name
- NCT00390975
- Testing
- Tegaserod
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Novartis
Alzheimer Disease, Gastric Retention
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules Containing Memantine Hydrochloride in Healthy Adults
To assess how long memantine hydrochloride (HCl) (50 mg) extended release capsules stay in the stomach as determined by imaging assessment (MRI or abdominal ultrasound).
- Conditions
- Alzheimer Disease, Gastric Retention, Healthy
- Trial name
- NCT03711825
- Testing
- LYN-057, Imaging Assessment (MRI), Imaging Assessment (U/S)
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Gastric Cancer Stage, Esophageal Cancer
Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy
Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients.
- Conditions
- Gastric Cancer Stage, Esophageal Cancer, Gastroparesis
- Trial name
- NCT07104214
- Where
- 3 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Zhejiang University
ARDS (Moderate or Severe), Prone Position
The PRE-VAIL Study
During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe…
- Conditions
- ARDS (Moderate or Severe), Prone Position, Enteral Nutrition Feeding, Intensive Care Unit (ICU) Admission
- Trial name
- NCT07176624
- Testing
- Enteral nutrition is reduced before the prone position
- Where
- China
- Volunteers
- 259 people
- Sponsor
- The First Hospital of Jilin University
Feeding Intolerance, Premature Birth
Multi-Center Study of Different Doses Domperidone in Feeding Intolerance
The purpose of this clinical multi-center study is to determine whether different doses of domperidone are effective in the treatment of feeding intolerance in premature infant
- Conditions
- Feeding Intolerance, Premature Birth, Domperidone Overdose, Gastric Retention
- Trial name
- MCSDDDFI (NCT02980250)
- Testing
- Low dose, normal dose, over dose
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Retention, Healthy
Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects
To assess how long modified release (MR) memantine hydrochloride prototype capsule formulations stay in the stomach as determined by magnetic resonance imaging (MRI).
- Trial name
- NCT03468543
- Testing
- Memantine Hydrochloride MR Prototype Capsule Formulation A, Memantine Hydrochloride MR Prototype Capsule Formulation B, Memantine Hydrochloride MR Prototype Capsule Formulation C
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Healthy
The Gastric Residence Time (GRT) of Soctec Capsule After a Standardized Breakfast
The primary objective of the study was to assess the gastric residence time (GRT) of the Soctec capsule after a standardized breakfast. 12 healthy subjects will undergo an initial screening visit.
- Trial name
- NCT02335515
- Testing
- Soctec
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- SkyePharma AG
Gastroretentive Drug Formulation of Furosemide, Oedema
Magnetic Marker Monitoring of Furosemide-containing Gastroretentive Formulation in Healthy Male Subjects (Fasting and Fed Conditions)
Furosemide is a diuretic drug, used in the treatment of oedematous states associated with cardiac, renal, and hepatic disorder, and may be effective in patients unresponsive to thiazide diuretics.
- Trial name
- NCT01887379
- Testing
- GRDF furosemide
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- LTS Lohmann Therapie-Systeme AG
Gastric Retention
Impact of a One-Week Discontinuation of Semaglutide on Gastric Retention and Endoscopic Mucosal Visibility Scores
A prospective, single-center, observational study to compare the risk of gastric retention and endoscopic mucosal visibility between the exposure group (one-week discontinuation of semaglutide before EGD) and non-exposure group…
- Trial name
- NCT07152756
- Testing
- Esophagogastroduodenoscopy
- Where
- China
- Volunteers
- 418 people
- Sponsor
- Fudan University
Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of Dulaglutide (LY2189265) affect the amount of food and drink that stays in your stomach after a meal.
- Trial name
- GBGT (NCT07313813)
- Testing
- Dulaglutide
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Eli Lilly and Company
Gastroparesis
IS There a Correlation Between Sypmtoms of Gastroparesis and the Duration of Video Caspule Retention in the Stomach
Gastroparesis is a syndrome characterized by delayed gastric emptying in absence of mechanical obstruction of the stomach. The cardinal symptoms include postprandial fullness (early satiety), nausea, vomiting, and…
- Trial name
- NCT01858220
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Type 2 Diabetes
Clinical Trail of Tang-min-Ling Pills in Type 2 Diabetes Mellitus
This is a randomized, doubled blind, dose-paralleled control, multi-centre clinical trail,to evaluate the efficacy of Tang-min-ling pills in the treatment of type 2 diabetes mellitus.
- Trial name
- NCT01087242
- Testing
- Tang-min Lin pill
- Where
- 4 sites in China
- Volunteers
- 480 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences