Clinical trials: Gastric Submucosal Tumors
Stomach Neoplasms
The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD
This will be a single-centre, randomised, endoscopist-blind, parallel-group study in patients who are scheduled endoscopic submucosal dissection (ESD) for gastric mucosal lesion.
- Trial name
- NCT02730533
- Testing
- Esomeprazole, No PPI treatment
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST)
Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor Diagnosis
This study develops a multimodal AI model using endoscopic ultrasound, white-light endoscopy, and clinical information to support the diagnosis of upper GI mesenchymal tumors and the risk stratification of gastric GISTs.
- Conditions
- Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST), Leiomyoma, Schwannoma
- Trial name
- NCT07078136
- Testing
- Multimodal AI Model, Expert Endoscopist Assessment
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Stomach Cancer, Undifferentiated Type
Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type
This multi-center, randomized controlled trial is designed to evaluate clinical effectiveness and cost-effectiveness of ESD for undifferentiated type of EGC meeting the expanded indication compared with surgery.
- Conditions
- Stomach Cancer, Undifferentiated Type, Expanded Indication of Endoscopic Resection
- Trial name
- ERASE-GC (NCT04890171)
- Testing
- Endoscopic submucosal dissection, Surgery
- Where
- South Korea
- Volunteers
- 708 people
- Sponsor
- National Cancer Center, Korea
Early Gastric Cancer
Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection for Early Gastric Cancer
The purpose of this study is to determine whether Endoscopic Submucosal Dissection combine with Laparoscopic Regional Lymph node Dissection for early gastric cancer can improve Disease-free survival ？
- Trial name
- NCT02325999
- Testing
- ESD AND LRLD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Submucosal Tumor of Gastrointestinal Tract
Diagnostic Accuracy of SurePath™ in EUS-FNA
It is a prospective randomized controlled study to evaluate the diagnostic accuracy of SurePath™ liquid-based cytology in endoscopic ultrasound-guided sampling.
- Trial name
- NCT05394129
- Testing
- SurePath™
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Seoul National University Hospital
Adenoma, Villous
Outcomes of Endoscopic Resection of Mucosal and Submucosal Lesions in the Stomach
A patient referred to have a lesion in the stomach removed. The aims of this study are to collect information on the technique of endoscopic removal of such lesions.
- Trial name
- OERS (NCT02306707)
- Testing
- Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Professor Michael Bourke
Submucosal Tumor of Stomach
Submucosal Tumor Removal by Endoscopic Excision Therapy
Smaller submucosal tumors (SMT) in the stomach are usually seen as an incidental finding during a gastroscopy, although current diagnostics usually do not clearly indicate what type of tumor it is.
- Trial name
- STREET (NCT04913077)
- Testing
- removal of submucosal gastric tumor preferably by Full Thickness Resection Device (FTRD)
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Gastric Cancer Stage
Expanded Indications of Endoscopic Submucosal Dissection for Early Gastric Cancer in China
Background: The main treatment methods for early gastric cancer (EGC) include endoscopic submucosal dissection (ESD) and radical gastrectomy.
- Trial name
- NCT06869356
- Testing
- D2 gastrectomy
- Where
- China
- Volunteers
- 1,291 people
- Sponsor
- Beijing Friendship Hospital
Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection
Endoscopic Resection of Gastrointestinal Neoplasms
The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare…
- Conditions
- Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection, Gastric Neoplasm, Colonic Neoplasms
- Trial name
- NCT04780256
- Testing
- Endoscopic resection
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Gastric Cancer
The Efficacy of Serum Pepsinogen for Prediction of Metachronous Gastric Neoplasm
After endoscopic resection of early gastric cancer (EGC), there remained concerned about the development of the metachronous gastric neoplasm (MGN). The aim of this study was to evaluate the role of H.
- Trial name
- NCT02682446
- Testing
- H pylori eradication
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Early Gastric Cancer, Gastric Dysplasia
Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing
Endoscopic submucosal dissection (ESD) is an established treatment for early gastric cancer and precancerous lesions. Post-ESD artificial ulcers may lead to complications including delayed bleeding (3-15%) and prolonged healing.
- Conditions
- Early Gastric Cancer, Gastric Dysplasia, Gastric Neoplasms, Peptic Ulcer With Haemorrhage
- Trial name
- NCT07312370
- Testing
- Esomeprazole (Intravenous), Esomeprazole (Oral), Sucralfate Suspension
- Where
- China
- Volunteers
- 120 people
- Sponsor
- LanZhou University
Gastric Adenoma, Gastric Cancer
Efficacy of Bispectral Index Monitoring for Midazolam and Meperidine Induced Sedation During Endoscopic Submucosal Dissection
Background: Endoscopic submucosal dissection (ESD) usually requires adequate level of sedation due to lengthy and uncomfortable procedure.
- Trial name
- NCT01157598
- Testing
- bispectral index monitoring
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Early Gastric Cancer
Usefulness of Probe-based Confocal Laser Endo-microscopy in Delineation of Margin of Early Gastric Cancer for Endoscopic Submucosal Dissection
The aim of this study is to evaluate the usefulness of pCLE (probe-based confocal laser endomicroscopy) compared with conventional chromoendoscopy (CE) for delineating the margin of early gastric cancer (EGC) with endoscopic…
- Trial name
- NCT02189226
- Testing
- Endoscopic submucosal dissection (ESD) with or without probe-based confocal laser endomicroscopy (pCLE)
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Yonsei University
Esophageal Carcinoma, Gastric Carcinoma
Detection of Upper Gastrointestinal Tumour Depth and Demarcation Using Systemic Administration of Indocyanine Green During Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is a relatively new technique to treat superficial cancers in the upper gastrointestinal (GI) tract. Previous studies reported high en bloc resection rates (95%-97%).
- Trial name
- BRIGHT (NCT07108855)
- Testing
- Indocyanine Green (IC-Green), Fluorescence guided identification using indocyanine green
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Early Gastric Cancer, Endoscopic Submucosal Dissection
Safety and Efficacy of Traction Robot-assisted Endoscopic Submucosal Dissection for Early Gastric Cancer
The goal of this clinical trial is to investigate whether the flexible auxiliary single-arm transluminal endoscopic robot (FASTER) system can improve the safety of the endoscopic submucosal dissection (ESD).
- Conditions
- Early Gastric Cancer, Endoscopic Submucosal Dissection, Robot Surgery
- Trial name
- NCT06748352
- Testing
- FASTER-assisted ESD, Conventional ESD
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shandong University
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Gastric Cancer, Colon Cancer
Assessing How the Viscosity of Submucosal Gel Injections Helps With Endoscopic Mucosal Resections
This is a study to determine how the viscosity (thickness) of an FDA approved gel affects the ease in which endoscopic mucosal resections (EMR) can be performed.
- Trial name
- NCT02519140
- Testing
- Cook Medical EMR Gel
- Where
- United States
- Sponsor
- Antonios Likourezos
Early Gastric Cancer
Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer
The investigators compared the perioperative, oncological, functional and immunological outcomes of endoscopic submucosal dissection against laparoscopic assisted gastrectomy for treatment of early gastric cancer.
- Trial name
- LGE (NCT03136354)
- Testing
- Endoscopic Submucosal Dissection, Laparoscopic assisted Gastrectomy
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Gastric Cancer, Colon Cancer
Safety and Efficacy of Using MASTER to Perform Endoscopic Submucosal Dissection in Human
This trial is to evaluate the safety and efficacy of using MASTER, a robotics enhanced endosurgical system to perform endoscopic submucosal dissection (ESD) of gastric/colon cancer in human.
- Trial name
- NCT01464918
- Testing
- Endoscopic submucosal dissection (ESD) using device, MASTER
- Where
- 3 sites in China, India and 1 more
- Volunteers
- 7 people
- Sponsor
- National University Hospital, Singapore
Gastric Cancer, Colon Nos Polypectomy Tubular Adenoma
Phase III Open-labeled Study of NPO-11 in Patients Undergoing Therapeutic Upper Gastrointestinal Endoscopy
Patients who require therapeutic upper gastrointestinal endoscopy, such as polypectomy, endoscopic hemostasis, percutaneous endoscopic gastrostomy (PEG), endoscopic mucosal resection (EMR) and endoscopic submucosal dissection…
- Conditions
- Gastric Cancer, Colon Nos Polypectomy Tubular Adenoma, Gastric Adenoma
- Trial name
- NCT01411189
- Testing
- Menthol
- Where
- Japan
- Volunteers
- 33 people
- Sponsor
- Nihon Pharmaceutical Co., Ltd