Clinical trials: Gastric Surgery
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Esophageal Cancer, Surgery Indication
Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer
Malnutrition is common at the time of diagnosis of esogastric cancers. However, there are no recommendations regarding preoperative nutritional support (type and duration) or on the impact of refeeding on postoperative morbidity…
- Conditions
- Esophageal Cancer, Surgery Indication, Malnourished, Neoadjuvant Treatment
- Trial name
- FREJENO (NCT07584577)
- Testing
- Enteral or parenteral nutrition
- Where
- France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Bordeaux
Gastric Cancer
A Multicenter Phase II Study of Neoadjuvant Docetaxel, Cisplatin and Capecitabine and Protocolized Surgery in Resectable Gastric Cancer
The purpose of this study is to determine the feasibility of chemotherapy, consisting of docetaxel, cisplatin and capecitabine given prior to surgery for stomach cancer.
- Trial name
- DoCCS (NCT01517009)
- Testing
- Docetaxel, cisplatin, Capecitabine
- Where
- 5 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Obesity
5 and 7-year Follow-up of the YOMEGA Trial Cohort
Over the last 40 years, the Roux-en-Y Gastric Bypass (RYGB) has been the gold standard in the surgical management of morbid obesity. and is a validated bariatric procedure in France.
- Trial name
- YOMEGA 5-7y (NCT05549271)
- Testing
- Laparoscopic Mini-gastric bypass, Laparoscopic Roux-en-Y Gastric ByPass (RYGBP)
- Where
- 9 sites in France
- Volunteers
- 248 people
- Sponsor
- Hospices Civils de Lyon
Anxiety, Gastric Carcinoma
Educational Brochure in Preparing Patients With Gastric Cancer and Their Caregivers for Recovery After Surgery
This pilot clinical trial studies an educational brochure in preparing patients with gastric cancer and their caregivers for recovery after surgery.
- Conditions
- Anxiety, Gastric Carcinoma, Stress
- Trial name
- NCT02334332
- Testing
- Educational Intervention, Standard Follow-Up Care, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Bariatric Surgery
MINI Bypass Versus Roux-en-Y Bypass: Differences in HOrmonal Secretions at 2 Years of Surgery
Gastric bypass with omega loop technic (OLGB) seems to be as effective as gastric bypass roux-en-Y (RYGB the reference) for the management of obesity and type 2 diabetes, but with less early surgical complications and more…
- Trial name
- MINIBHO (NCT03482895)
- Testing
- Blood sampling, Feces sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Esophageal Cancer, Gastric Cancer
Cisplatin and Irinotecan Chemotherapy, Followed by ZD 1839 (Iressa) in Patients With Esophageal or Gastric Carcinomas
This study is for patients with esophageal, esophagogastric, or gastric cancer that has spread to other parts of the body. The purpose of this study is to test the safety and effectiveness of a new experimental drug called ZD…
- Trial name
- NCT00215995
- Testing
- Cisplatin, Irinotecan, ZD 1839
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 21 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Full Stomach
Gastric Assessment Ambulatory Surgery
The surgical procedures in outpatient surgery are in perpetual increase. However, the peri operative stress can reduce the gastric emptying. A patient's compliance for following the fasting rules cannot be controlled at home.
- Trial name
- GAAS (NCT03352401)
- Testing
- Ultrasouund assessment of gastric contents
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Gastric Cancer, Complement Component Deficiency
The Predictive Value of Complement C3 in Patients With Advanced Gastric Cancer
This study is designed to investigate whether complement C3 depletion is associated with poor short-term outcomes in postoperative patients with gastric cancer.
- Conditions
- Gastric Cancer, Complement Component Deficiency, Surgery
- Trial name
- NCT02425930
- Testing
- gastrectomy plus D2 lymphadenectomy, S-1+Oxaliplatin
- Where
- China
- Volunteers
- 85 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Obesity, Morbid
Wound Repair and Body Contouring Surgery After Gastric Bypass
The primary aim of our study is to test the hypothesis that wound healing is impaired in the patient who has experienced massive weight reduction following gastric bypass for morbid obesity.
- Trial name
- NCT00609037
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Vanderbilt University
Pulmonary Aspiration of Gastric Contents, Emergency Surgery
Gastric Ultrasound for Airway Management in Emergency Patients
This prospective observational cohort study evaluates the association between gastric residual content and volume, assessed by point-of-care gastric ultrasound (PoCUS), and the choice of airway management technique (Rapid…
- Conditions
- Pulmonary Aspiration of Gastric Contents, Emergency Surgery, Gastric Residual Volume, Airway Management
- Trial name
- NCT07640165
- Testing
- Preoperative Gastric Point-of-Care Ultrasound (PoCUS)
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Universitas Indonesia
Surgery, Obesity
A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients
The aim of the study is to demonstrate the superiority of bariatric surgery on the disappearance of NASH without worsening of fibrosis in comparison to medical standard treatment in obese patients (35 kg/m² > BMI ≥ 30 kg/m²) with…
- Conditions
- Surgery, Obesity, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
- Trial name
- NASHSURG (NCT03472157)
- Testing
- Lifestyle therapy, Bariatric surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Lille
Successful Conversion Rate of Operation, Unresectable Gastric Cancer
Intra-arterial Infusion Chemotherapy Combined With Sodium Bicarbonate for Unresectable Gastric Cancer
This project intends to compare the clinical effects and side effects of three kinds of treatment methods in the treatment of unresectable gastric cancer by intra-arterial catheter infusion chemotherapy combined with sodium…
- Trial name
- NCT03822130
- Testing
- Arterial catheter infusion chemotherapy, Sodium Bicarbonate, Systemic Chemotherapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia
Preoperative Optimization With Tirzepatide, Ketogenic Diet, or Standard Care Before One Anastomosis Gastric Bypass Surgery
This study compares three preoperative strategies before one anastomosis gastric bypass(OAGB) for severe obesity. Participants will be assigned to receive either tirzepatide medication for 60 days, a ketogenic diet for 4 weeks…
- Conditions
- Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and Dyslipemia, Obesity (BMI > 35) and High Blood Pressure
- Trial name
- OPTI-OAGB (NCT07622992)
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Mario Musella MD
Bariatric Surgery
Fat Absorption and Metabolism After Roux-en-Y Gastric Bypass
Using intravenous and oral administration of stable isotope tracers, we will investigate the importance of altered fat absorption and altered whole body fat metabolism for the reduced postprandial systemic TAG concentrations in…
- Trial name
- FAT-BAR (NCT04859816)
- Testing
- Metabolic test, DXA-scan, MRS
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Adenocarcinoma, Stomach Neoplasm
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of radiotherapy combined with chemotherapy and anti-PD-1 immunotherapy followed by surgery for the primary and metastatic lesions in patients with limited…
- Conditions
- Adenocarcinoma, Stomach Neoplasm, Gastroesophageal-junction Cancer, Oligometastatic Disease
- Trial name
- Miracle-G (NCT06121700)
- Testing
- Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antibody
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Fudan University
Morbid Obesity
Laparoscopic Gastric Plication Operation for Patients With Severe or Morbid Obesity
The purpose of this study is to collect data prospectively on the safety and efficacy of the Laparoscopic Gastric Plication operation for patients with Severe or Morbid Obesity.
- Trial name
- NCT01207609
- Testing
- Laparoscopic Gastric Plication
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Ponce, Jaime, M.D.
Obesity
Brain Activation in Response to Appetitive Cues Pre- and Post- Bariatric Surgery
Utilizing fMRI, this study will examine changes in BOLD signal as a proxy measure of brain activation in response to highly palatable (high energy density [kcal/g]), less palatable and non-food stimuli in severely obese women…
- Trial name
- NCT01590914
- Testing
- Fed Condition, Fasted Condition
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- New York Obesity and Nutrition Research Center
Type 2 Diabetes, Morbid Obesity
The Effect of a Gastric Bypass on Type 2 Diabetes in the Morbidly Obese Patient
Proof of concept, of RYGBP and its capabilities to cure type 2 diabetes (DM 2) and sleep apnea has already been recognized in the reports on weight loss surgery.
- Trial name
- NCT01086111
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Gasthuisberg
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