Clinical trials: Gastric Symptoms
Bleeding Gastric Varices, Liver Cirrhosis
A Randomized Trial of GVS Alone vs. Propranolol
Design a randomized trial to compare the effect of endoscopic cyanoacrylate injection obliteration versus non-selective beta-blocker in the primary prevention of gastric variceal bleeding.
- Trial name
- P-GVO (NCT01298271)
- Testing
- propranolol
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Bariatric Surgery Candidate, Obesity
Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial
The purpose of this study is to assess the safety and efficiency of OAGB compared to RYGB
- Conditions
- Bariatric Surgery Candidate, Obesity, Obesity, Morbid
- Trial name
- Roux-en-WHY? (NCT04852198)
- Testing
- OAGB, RYGB
- Where
- 2 sites in Netherlands
- Volunteers
- 298 people
- Sponsor
- Flevoziekenhuis
Obesity, Diabetes Mellitus, Type 2
Slowly Digestible Carbohydrates and the Ileal Brake
The ileal brake is a feedback mechanism controlling stomach-mediated transit of a meal, for which gastric emptying can be used as an indicator.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Appetitive Behavior
- Trial name
- NCT03630445
- Testing
- Isomaltooligosaccharides (IMOs), Xtend® sucromalt, Combination of IMOs and Xtend® sucromalt
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Morbid Obesity
Laparoscopic Adjustable Gastric Banding as a Treatment for Morbid Obesity in Adolescents
The purpose of this study is to determine whether the LAP-BAND system is safe and effective in morbidly obese adolescents.
- Trial name
- NCT00592202
- Testing
- Placement of an adjustable gastric band
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Illinois Chicago
Anal Cancer, Colorectal Cancer
Assessment of Symptom-Related Cytokines in Lung and Gastrointestinal (GI) Cancer Patients
Primary Objectives: To determine the feasibility of a study that would describe changes of certain circulating inflammatory cytokines (interleukin-1, 6, 8, 10, 12, and tumor necrosis factor-alpha [TNF] and symptoms related to…
- Conditions
- Anal Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00502502
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity
Surgical Treatment for Morbid Obesity by Sleeve Gastrectomy Versus Gastric Bypass
The aim of this study is to assess that the sleeve gastrectomy can improve the risk benefit than the gastric bypass
- Trial name
- SLEEVE (NCT00722995)
- Testing
- Sleeve gastrectomy, Gastric Bypass
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metastatic Solid Tumor, Colorectal Cancer
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
This open-label, phase Ib/II study of surufatinib in combination with tislelizumab will evaluate the safety, tolerability, PK and efficacy in patients with advanced solid tumors.
- Conditions
- Metastatic Solid Tumor, Colorectal Cancer, Neuroendocrine Tumors, Small Cell Lung Cancer
- Trial name
- NCT04579757
- Testing
- Surufatinib and Tislelizumab _ Part 1, Surufatinib and Tislelizumab _ Part 2
- Where
- 18 sites in United States
- Volunteers
- 87 people
- Sponsor
- Hutchmed
Diabetes, Metabolism and Nutrition Disorder
Trial Investigating the Effect of Semaglutide on Energy Intake, Appetite Sensations, Postprandial Glucose and Triglyceride Metabolism and Gastric Emptying in Obese Subjects Compared With Placebo
This trial is conducted in Europe. The aim of the trial is to investigate the effect of semaglutide on energy intake, appetite sensations, postprandial glucose and triglyceride metabolism and gastric emptying in obese subjects…
- Conditions
- Diabetes, Metabolism and Nutrition Disorder, Obesity
- Trial name
- NCT02079870
- Testing
- semaglutide
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Obesity, Type 2 Diabetes Mellitus
Impact of GBS on CVD in Type 2 Diabetes Mellitus
This research is a NIH single site study with the aims to (1) determine whether surgically induced weight loss decreases the risk of CVD in morbidly obese subjects with T2DM.
- Trial name
- NCT00787670
- Testing
- Diabetes Support and Education, gastric bypass surgery, Tissue Control Group
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Gastroparesis, Idiopathic Gastric Motility Disorder
Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests to assess the pyloric…
- Conditions
- Gastroparesis, Idiopathic Gastric Motility Disorder, Diabetic Gastroparesis
- Trial name
- PSAGS (NCT04661215)
- Where
- 5 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastrointestinal Neoplasms, Adenocarcinoma
A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer
The Phase 1b study is an open-label, multicenter dose escalation study designed to assess the safety, tolerability, immunogenicity and recommended phase 2 dose (RP2D) of IMU-131.
- Trial name
- NCT02795988
- Testing
- IMU-131, Cisplatin and either Fluorouracil (5-FU) or Capecitabine or Oxaliplatin and capecitabine.
- Where
- 22 sites in Georgia, India and 5 more
- Volunteers
- 64 people
- Sponsor
- Imugene Limited
Liver Cirrhosis, Esophageal and Gastric Varices
A Randomized Controlled Study on the Treatment of Cirrhosis Combined With Hypersplenism
The purpose of this study was to compare the effects of partial splenic artery embolization combined with endoscopic treatment and endoscopic treatment alone on portal hypertension in cirrhosis with hyperplenism or splenomegaly…
- Conditions
- Liver Cirrhosis, Esophageal and Gastric Varices, Hypersplenism
- Trial name
- NCT05055713
- Testing
- Endoscopic therapy+ beta blockers, Endoscopic therapy+ PSE+beta blockers, Endoscopic therapy
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Qilu Hospital of Shandong University
Gastroparesis, Gastroparesis-like Syndrome
Pediatric Gastroparesis Registry
The objective of the Pediatric Gastroparesis Registry is to create a national prospective registry of children and adolescents with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but normal gastric…
- Trial name
- PGpR (NCT03680820)
- Where
- 3 sites in United States
- Volunteers
- 147 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastric Cancer, Hepatic Carcinoma
Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025…
- Conditions
- Gastric Cancer, Hepatic Carcinoma, Pulmonary Carcinoma, Pancreatic Carcinoma
- Trial name
- NCT07359586
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Zhejiang University
Obesity, Morbid, Surgery
Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
The aim of the study is to compare two different bariatric procedures performed in patients with 65 years or more: gastric bypass and sleeve gastrectomy.
- Conditions
- Obesity, Morbid, Surgery, Elderly
- Trial name
- BaSE (NCT03339791)
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Gastroparesis
Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial
A randomized clinical trial comparing endoscopic per-oral pyloromyotomy (POP) versus a control sham intervention (diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption) in patients with medically refractory…
- Trial name
- EMPTIES (NCT05039424)
- Testing
- Endoscopic per-oral pyloromyotomy (POP), Diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Matthew Allemang
Diabetes Mellitus Type 2 in Obese
DMBSS-A Randomized Trial of Different Laparoscopic Gastric Bypass Surgery in Patients With Obesity-related T2DM
The investigators would like to conduct a randomized clinical trial to compare the efficacy of diabetes treatment between different gastric bypass procedures involving type 2 diabetics patients with BMI from 27.5 to 35 kg/m2
- Trial name
- DMBSS (NCT01989988)
- Testing
- LMGB, LRYGB, SADJB
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Gastroesophageal Reflux, Fundoplication
Mayo Clinic Foregut Surgery Report Card Questionnaire
The Mayo Clinic Foregut Surgery Report Card Questionnaire has been created in order to have a consistent evaluation tool for patients undergoing foregut surgery in order to standardize and validate outcome measures.
- Conditions
- Gastroesophageal Reflux, Fundoplication, Hernia, Hiatal, Surveys and Questionnaires
- Trial name
- NCT02708303
- Testing
- Mayo Clinic Foregut Surgery Report Card Questionnaire
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Mayo Clinic
Advanced Solid Tumor, Metastatic Solid Tumors
Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET
A phase 1/2, first-in-human, open-label study of the safety, tolerability, PK, and efficacy of the novel MET/CSF1R/SRC inhibitor TPX-0022 in adult subjects with advanced or metastatic NSCLC, Gastric Cancer, or solid tumors…
- Conditions
- Advanced Solid Tumor, Metastatic Solid Tumors, MET Gene Alterations
- Trial name
- SHIELD-1 (NCT03993873)
- Testing
- elzovantinib (TPX-0022)
- Where
- 24 sites in United States, France and 3 more
- Volunteers
- 95 people
- Sponsor
- Turning Point Therapeutics, Inc.
Temperature Change, Body, Supraglottic Airway Device
Feasibility and Accuracy of Core Temperature Measurements Using the Esophageal Temperature Probe Inserted Through the Gastric Lumen of Supraglottic Airway Device in Pediatrics
In pediatric patients, the accuracy of body temperature measured with an esophageal temperature probe placed through the gastric lumen of the supraglottic airway device is investigated.
- Conditions
- Temperature Change, Body, Supraglottic Airway Device, Pediatric ALL
- Trial name
- NCT05705206
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Asan Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.