Clinical trials: Gastritis H Pylori
Helicobacter Pylori, Gastritis
Safety and Immunogenicity of Chiron's Investigational H. Pylori Vaccine in Healthy Adults
This study was designed to investigate the safety and immunogenicity of Chiron's investigational H. pylori (HP3) vaccine
- Conditions
- Helicobacter Pylori, Gastritis, Gastric Cancer, Gastroduodenal Ulcers
- Trial name
- NCT00613665
- Testing
- helicobacter pylori vaccine
- Where
- Germany
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Stomach Neoplasms, Atrophic Gastritis
OLGA and OLGIM Stage System for Gastric Cancer
To validate OLGA and OLGIM staging system with serum pepsinogen for estimating GC risk according to Lauren's histologic classification in South Korea.
- Conditions
- Stomach Neoplasms, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT03380052
- Where
- South Korea
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori, Atrophic Gastritis
Helicobacter Pylori, Atrophic Gastritis and Intestinal Metaplasia Registry and Prospective Study
Since much is unknown about factors that lead to progression of the pre-neoplastic lesions and cancer. In addition, there is ongoing debate on the optimal surveillance intervals and techniques.
- Conditions
- Helicobacter Pylori, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT05053945
- Testing
- Esophagogastroduodenoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Functional Dyspepsia, Gastritis
The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter Spp. in Well-defined Gastric Diseases and (Pre-) Malignancies
The goal of this clinical trial is to discover the prevalence of NHPH bacteria (Non-Helicobacter pylori Helicobacter species) in patients with one of the following conditions: 1.
- Conditions
- Functional Dyspepsia, Gastritis, Gastritis Chronic, Gastric Cancer (GC)
- Trial name
- HELIS (NCT07770126)
- Where
- 3 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
HELICOBACTER PYLORI INFECTIONS
miRNA in Pediatric Gastritis
The goal of this clinical trial is to assess the differential expression of miR-155 and miRNA-204 in relation to gastritis, and assess their relation with the presence of H. pylori in children.
- Trial name
- microRNA (NCT07300787)
- Testing
- miRNA gene expression
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Helicobacter Pylori Infection, Gastritis
Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection
Helicobacter pylori is a pathogenic bacteria transmitted from individual to individual, being scientifically recognized as an agent who causes persistent inflammatory activity on the gastric mucosa.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Gastric Cancer
- Trial name
- NCT05100446
- Testing
- Amoxicillin - high dose dual therapy, Pylera, Esomeprazole 40mg
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Helicobacter Pylori, Gastric Antrum
Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study
There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori…
- Conditions
- Helicobacter Pylori, Gastric Antrum, CORPUS BIOPSIES
- Trial name
- NCT02675010
- Testing
- ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gastritis
i-Scan for the Detection of Helicobacter Pylori
This study aims to assess whether iScan, an intra-endoscopic imaging technique is an accurate and reliable tool in detecting and characterising Helicobacter pylori (H pylori) and comparing this to standard endoscopic imaging with…
- Trial name
- NCT02385045
- Testing
- i-scan, narrow band imaging
- Where
- United Kingdom
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Gastritis H Pylori
Correlation Between H.Pylori Colonization and Gastritis
To study the prevelance rate of H.pylori colonization in patients with gastritis. To correlate the H.pylori colonization with endoscopic finding.
- Trial name
- NCT06015763
- Testing
- Endoscopy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Merna Mawgoud Zaki Bechit
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study was to evaluate the efficacy and safety of the triple therapy of berberine hydrochloride, vonorasan and amoxicillin for the primary eradication of Helicobacter pylori.It is hypothesized that berberine…
- Trial name
- NCT06514274
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
H.Pylori Infection, H.Pylori Gastrointestinal Disease
Concomitant Versus Hybrid Regimen for H. Pylori Eradication
10 day concomitant versus 14 day hybrid regimen as first line H. pylori eradication treatment in a high clarithromycin resistance area. A multicenter, randomized, equivalence trial.
- Conditions
- H.Pylori Infection, H.Pylori Gastrointestinal Disease, H. Pylori Associated Phlegmonous Gastritis
- Trial name
- NCT03592069
- Testing
- 10 day concomitant regimen, 14 day hybrid regimen
- Where
- Greece
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Neoplasm, Stomach, H. Pylori Infection
Early Detection and Screening Strategy of Gatric Cancer in Sichuan Province-A Prospective Cohort Study (WCH-GC-SIGES-01)
To establish prospective cohort of healthy population and corresponding serum sample bank in Sichuan province to provide platform for exploring early diagnosis and screening strategy of gastric cancer by a prospective cohort…
- Conditions
- Neoplasm, Stomach, H. Pylori Infection, Chronic Atrophic Gastritis
- Trial name
- SIGES-01 (NCT03597672)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jian-Kun Hu
Bile Reflux Gastritis, Gastric Cancer
Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Cross-sectional Study.
To explore the effects of bile reflux on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
- Conditions
- Bile Reflux Gastritis, Gastric Cancer, Helicobacter Pylori Infection, Intestinal Metaplasia
- Trial name
- NCT03976739
- Where
- China
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study is to assess the efficacy and safety of berberine, amoxicillin and vonoprazan containing triple therapy in Helicobacter Pylori first-line eradication.
- Trial name
- NCT05014334
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastritis Chronic, Gastroduodenitis
To Develop Methods for the Rehabilitation of Chronic Gastroduodenal Pathology in Children.
The object of the study will be children and adolescents from 6 to 15 years old, living in the city of Tashkent and in the Tashkent region.
- Conditions
- Gastritis Chronic, Gastroduodenitis, Peptic Ulcer, Duodenal Ulcer
- Trial name
- NCT04702542
- Testing
- Enteral oxygen therapy
- Where
- Uzbekistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan
Helicobacter Pylori Infection, Chronic Gastritis
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
The aim of this study is to evaluate the efficacy and safety of a quadruple therapy consisting of berberine hydrochloride, minocycline, esomeprazole, and colloidal bismuth tartrate for the first phase eradication of Helicobacter…
- Trial name
- NCT06603688
- Testing
- esomeprazole, Bismuth, Amoxicillin
- Where
- China
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection, Helicobacter Pylori Gastritis
Helicobacter Pylori Local Prevalence and Antibiotic Resistance
The clinical management of H. pylori infection depends essentially on two factors, prevalence and local resistance. In Germany, only limited data from rather small cohorts currently exist regarding both factors.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Pylori Gastritis, Drug Resistant Bacterial Infection, Antibiotic Resistant Infection
- Trial name
- HelicoPTER (NCT05561504)
- Where
- Germany
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gastric Microbiota, Non-atrophic Gastritis
Difference of Gastric Microbiota in the Process of Correa's Model.
Helicobater pylori plays an important role in the development of gastric cancer. Eradication therapy can reducing the morbidity of gastric cancer, but can't totally prevent it especially when atrophy and more serious precancerous…
- Conditions
- Gastric Microbiota, Non-atrophic Gastritis, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02833363
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori Infections, Atrophic Gastritis
Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality
Currently no ideal preventive modalities are available for reducing gastric-cancer caused mortality in organized population-based application.
- Conditions
- Helicobacter Pylori Infections, Atrophic Gastritis, Gastric Cancer
- Trial name
- GISTAR (NCT02047994)
- Testing
- Triple therapy
- Where
- Latvia
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer