Clinical trials: Gastro Intestinal Surgery
Gastroesophageal Reflux, Bariatric Surgery
the Related Factors of Bariatric Surgery on Gastroesophageal Reflux Disease
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including…
- Trial name
- NCT03497494
- Testing
- 2 cm away from the pylorus edge, 4 cm away from the pylorus edge, 6 cm away from the pylorus edge
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Periodontitis, Inflammatory Bowel Diseases
The Effect of Non-Surgical Periodontal Therapy on Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disease of the gastrointestinal tract characterised by complex interactions between genetic susceptibility, environmental factors, microbiota and host…
- Trial name
- NCT06245278
- Testing
- ELISA (Enzyme-Linked ImmunoSorbent Assay)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biruni University
Overweight and Obesity, Type 2 Diabetes
Fat Metabolites and Gut Hormones
To investigate the effects of different fat metabolites on gut hormone secretion in gastric bypass operated subjects and BMI-matched controls.
- Conditions
- Overweight and Obesity, Type 2 Diabetes, Bariatric Surgery, Gut Hormones
- Trial name
- NCT03223389
- Testing
- C-8 dietary oil, Tricaprylin, Olive oil
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative
Antireflux Suture In One Anastomsis Gastric Bypass
To prevent refulx symptoms in a type of bariatric surgery, a suture is taken.there is no enough evidence in support of or against the suture.
- Trial name
- NCT07148492
- Testing
- Antireflux suture, No Antireflux suture
- Where
- Pakistan
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic
Predictive Model For Anastomotic Leakage After Colorectal Cancer Surgery
This pilot study aimed to develop a simplified early postoperative model for AL risk stratification using readily available clinical and laboratory variables.
- Conditions
- Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic, Surgery Complications
- Trial name
- Doesn't exist (NCT07709923)
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Morbid Obesity, Metabolic Syndrome
FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT
This double-blinded proof-of-concept study is proposed to explore the effects of fecal microbiota transfer (FMT) in human subjects.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Diabetes, PreDiabetes
- Trial name
- DACH (NCT06268990)
- Testing
- Fecal microbiota transplantation
- Where
- Austria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wiebke Kristin Fenske
Delirium - Postoperative, Opioid-Free Anaesthesia
Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
Background Postoperative delirium (POD) is a common acute and transient form of brain dysfunction in elderly patients following surgery that can lead to serious adverse clinical outcomes and even death.
- Trial name
- NCT06958393
- Testing
- Dexmedetomidine, Esketamine, Esmolol
- Where
- China
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Hypotension on Induction
Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal…
- Trial name
- NCT05891951
- Testing
- Fluid therapy under the guide of Carotid ultrasound
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Min Su
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Acupuncture, Ear, Gastroparesis
The Role of AAT After Abdominal Surgery Based on RWS
Delayed gastric emptying (DGE) after surgery mainly occurs after gastrointestinal surgery A functional gastric emptying disorder, clinically characterized by weak or absent gastric peristalsis, gastric motility disorders, or…
- Trial name
- NCT06580197
- Testing
- Auricular Acupoint Therapy
- Where
- China
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gastroesophageal Reflux Disorder
Assessing Outcomes After Surgery for Gastroesophageal Reflux Disorder
The purpose of this study is to review pre-operative studies and patient evaluation reports and compare those with the results of the post-operative studies, patient evaluation reports and subjective patients' outcomes following…
- Trial name
- GERD (NCT00518505)
- Testing
- Symptom questionnaire
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Gastroesophageal Reflux, Obesity
Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
The planned research is to analyze the occurrence of gastroesophageal reflux disease (GERD) before and after sleeve gastrectomy (SG).
- Trial name
- SLEEFLUX (NCT05486169)
- Testing
- Sleeve Gastrectomy
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Bowel Disease, Liver Diseases
The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
Major abdominal surgery - like non-laparoscopic bowel resection, liver, gastric, or pancreas surgery - is performed under general anesthesia.
- Conditions
- Bowel Disease, Liver Diseases, Pancreas Disease, Anesthesia; Functional
- Trial name
- NCT04021264
- Testing
- Ropivacaine-Sufentanil, Dextrose 5
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Gastrointestinal Cancer, Sarcopenia
Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery
This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Cancer, Sarcopenia, Neuromuscular Blockade
- Trial name
- NCT07003061
- Testing
- Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Abdominal Surgery
Effect of Hot Pack Application on Gastrointestinal Motility After Abdominal Surgery
Study Title: The Effect of Hot Water Pack Application to the Lumbar Region on Gastrointestinal Motility in Postoperative Abdominal Surgery Patients Study Type: Interventional (Randomized Controlled Trial) Study Design…
- Trial name
- NCT06892782
- Testing
- Hot Water Pack Application
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Gastric Cancer, Salutogenesis
Immunonutrition and Psychosocial Factors in the Recovery of Patients After Gastrectomy: a Multidimensional Analysis
To conduct this research, the following guiding question was formulated: "Can immunonutrition, combined with the assessment of SOC and resilience, provide a broad view of the physical and psychological results during the…
- Conditions
- Gastric Cancer, Salutogenesis, Sense of Coherence
- Trial name
- NCT06578858
- Testing
- Application of questionnaires
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Gastrointestinal Function, Mental Well-being
The Effects of Early Postoperative Heat Application and Abdominal Massage on Gastrointestinal Function
This randomised controlled trial was designed to determine the effect of early-stage heat application and abdominal massage on patients' gastrointestinal function and mental well-being following hip fracture surgery.
- Trial name
- NCT07208955
- Testing
- heat application, abdominal massage, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Liver Cancer, Esophageal Cancer
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease…
- Conditions
- Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma
- Trial name
- TEG (NCT05517811)
- Testing
- TEG indices
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gastro Esophageal Reflux, Barrett Esophagus
PPI Therapy Impact on GERD After Sleeve Gastrectomy
The trial would to try to establish: The best post-operative PPI prescription protocol after Sleeve Gastrectomy The impact of PPI therapy on postoperative peptic diseases (erosive gastropathies, ulcers, duodenitis, esophagitis…
- Conditions
- Gastro Esophageal Reflux, Barrett Esophagus, Bariatric Surgery Candidate
- Trial name
- NCT04400136
- Testing
- Lansoprazole oral tablets 30 mg
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University