Clinical trials: Gastro-esophageal Reflux
Gastro-esophageal Reflux Disease With Ulceration.
Relationship of Obesity With GERD Among Nigerians
Obesity is a strong risk factor for GERD. This study assessed the role of obesity among patients having erosive GERD and controls.
- Trial name
- NCT02888808
- Testing
- Gastroscopy
- Volunteers
- 160 people
- Sponsor
- Obafemi Awolowo University Teaching Hospital
GERD
Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux
Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.
- Trial name
- NCT00584259
- Testing
- Coffee
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, Davis
GERD
Stretta Versus Conservative Treatment
Gastroesophageal reflux disease (GERD) is one of the most common diseases of the gastrointestinal tract. Obesity is a significant risk factor for GERD; however, treatment outcomes in obese patients remain challenging.
- Trial name
- NCT05781347
- Testing
- Radiofrequency Energy to the LES (Stretta Procedure), Stretta
- Where
- Czechia
- Volunteers
- 53 people
- Sponsor
- Military University Hospital, Prague
Gastro Esophageal Reflux Disease, Dyspepsia
Spirulina Platensis for PPI Withdrawal
Background: Rebound acid hypersecretion after proton pump inhibitors (PPIs) discontinuation may be accompanied by dyspepsia. Aim: To assess whether Spirulina platensis, by its anti-inflammatory properties, could minimize rebound…
- Conditions
- Gastro Esophageal Reflux Disease, Dyspepsia, Rebound Acid Hypersecretion
- Trial name
- SpAReDPPI (NCT04988347)
- Testing
- Spirulina platensis
- Volunteers
- 45 people
- Sponsor
- Universidade de Passo Fundo
Gastro Esophageal Reflux
Endoscopic Classification of Fundoplication Integrity Predicts Pathologic Reflux
This single-center, two-phase cohort study aimed to develop and validate a simple endoscopic classification of fundoplication integrity after anti-reflux surgery (ARS - Nissen or Toupet fundoplication).
- Trial name
- NCT07722663
- Where
- Italy
- Volunteers
- 153 people
- Sponsor
- IRCCS Policlinico S. Donato
Gastroesophageal Reflux
Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing
Patients with gastroesophageal reflux disease (GERD) are either treated for 4 weeks with a standard dose (20mg) of omeprazole, a drug of first choice, or by an individualized dosing (20 or 60mg/day) according how fast the patient…
- Trial name
- GERD (NCT00537732)
- Testing
- omeprazole
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Matthias Schwab
Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic
Kazakh Version of Reflux Symptom Index
Reflux symptoms index (RSI) were developed to identify a clinical index of suspicion for laryngopharyngeal reflux (LPR) in patients with ear, nose, and throat symptoms.
- Conditions
- Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic, Gastro Esophageal Reflux Disease
- Trial name
- NCT05296655
- Testing
- Reflux Symptom Index Inventory (diagnostic survey), Reflux finding score
- Where
- 2 sites in Kazakhstan
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Gastroesophageal Reflux, Heartburn
Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms.
The purpose of this study is to evaluate the effect of each of the rabeprazole treatment regimens on nocturnal heartburn symptoms.
- Trial name
- NCT00553449
- Testing
- rabeprazole
- Volunteers
- 48 people
- Sponsor
- Janssen-Ortho Inc., Canada
Irritable Bowel Syndrome, Gastro-oesophageal Reflux Disease
The Influence of Concomitant Irritable Bowel Syndrome on Gastro-Oesophageal Reflux Disease Symptoms and Severity.
This research aims to investigate whether there is a link between irritable bowel syndrome (IBS) and acid reflux, particularly whether there is a difference in acid reflux symptoms between people with and without IBS.
- Trial name
- NCT06615856
- Testing
- Questionnaire
- Volunteers
- 124 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Gastrectomy, Obesity
Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy
This study aims to compare the difference in staple usage and post-operative GERD (heartburn) between patients that had an endoscope used versus patients that had a suction calibration system used on them during "laparoscopic…
- Trial name
- NCT03939819
- Testing
- ViSiGi® 3D suction calibration device, Esophagogastroduodenoscopy (EGD) calibration
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Emory University
Gastroesophageal Reflux Disease, Gastritis
Analysis of Biopsies From the Upper Gastrointestinal Tract
Multicenter study to correlate histological findings in the upper gastrointestinal tract with endoscopic and clinical data.
- Trial name
- histoGERD (NCT01576289)
- Testing
- Histological analysis
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz
Gastro Esophageal Reflux
Esophageal pH-MII Duration: 12 or 24 Hours?
To check whether the first 12 hours of MII-pH recording are sufficient to diagnose gastroesophageal reflux disease (GERD) among newborns/infants, with a diagnostic accuracy similar to 24 hours of recording as currently advised.
- Trial name
- NCT05760274
- Testing
- multichannel intraluminal impedance and pH monitoring (MII/pH)
- Where
- Italy
- Volunteers
- 127 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gastric Ulcer, Duodenal Ulcer, Anastomotic Ulcer, Reflux Oesophagitis,"Non-erosive Reflux Disease, Zollinger-Ellison Syndrome
Nexium Capsules Clinical Experience Investigation
The purpose of this study is to confirm the safety profile / factors which impact safety and efficacy of Nexium capsules in daily clinical usage for the patients who have been prescribed Nexium for "gastric ulcer", "duodenal…
- Trial name
- NCT01434485
- Where
- 47 sites in Japan
- Volunteers
- 3,691 people
- Sponsor
- AstraZeneca
Gastro-esophageal Reflux, Reflux, Gastroesophageal
ARMA (Antireflux Mucosa Ablation) in Patients With Chronic Refractory Reflux Disease
Pilot study of the possible clinical response to anti reflux mucosal ablation in patients with chronic refractory reflux disease
- Trial name
- ARMA (NCT05425771)
- Testing
- Anti Reflux Mucosa Ablation
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Klinikum Garmisch-Patenkirchen
Aspiration Vomitus
Granisetron Versus Metoclopramide Effects on Gastric Volume by Sonographic Assessment on Patients Undergoing Caesarean Section.
Ultrasound assessment of the effect of metoclopramide versus granisetron on gastric volume in patients undergoing caesarean section study
- Trial name
- NCT04290026
- Testing
- metoclopramide versus granisetron
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Reflux Esophagitis (RE), Non-erosive Reflux Disease (NERD)
Analysis of GERD Symptoms Using Gastroesophageal Reflux Impact Score Questionnaire for Quality of Life
Even the patients complain GERD symptoms such as heartburn and acid regurgitation the final diagnosis could be reflux esophagitis (RE), non-erosive reflux disease (NERD) and even functional heartburn (FH).
- Conditions
- Reflux Esophagitis (RE), Non-erosive Reflux Disease (NERD), Functional Heartburn (FH)
- Trial name
- NCT01536080
- Where
- South Korea
- Volunteers
- 207 people
- Sponsor
- Seoul National University Bundang Hospital
Colon Polyp, Colon Disease
Endoscopy-related Phone Consultation During the COVID-19 Outbreak
The aim of this study is to evaluate patient and consultant experiences with phone consultations for endoscopy-related outpatient appointments during the COVID-19 outbreak.
- Conditions
- Colon Polyp, Colon Disease, Reflux, Gastroesophageal, Varices, Esophageal
- Trial name
- NCT04344964
- Testing
- None - NA
- Where
- Australia
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Austin Health
Cough, Asthma
Validation of the C-mo System - Cough Monitoring
The goal of this clinical study is to validate C-mo System's ability to automatically detect and characterise cough, in patients over 2 years old with cough as a key or refractory symptom.
- Conditions
- Cough, Asthma, Chronic Obstructive Pulmonary Disease, Gastro Esophageal Reflux
- Trial name
- C-mo_01 (NCT05989698)
- Testing
- C-mo System
- Where
- 8 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Cough Monitoring Medical Solutions
Clinically Severe Obesity, Inadequate Weight Loss
Laparoscopic Revision of Vertical Banded Gastroplasty to Gastric Bypass
The main aim of this study is to analyze and report the intermediate term outcomes after laparoscopic revision Roux-en-Y gastric bypass (RYGB) surgery for failed and/or complicated Vertical Banded Gastroplasty (VBG).
- Conditions
- Clinically Severe Obesity, Inadequate Weight Loss, Obesity Recidivism
- Trial name
- VBG (NCT01041131)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Osteoporosis, Achlorhydria
Does Omeprazole Decrease Intestinal Calcium Absorption?
The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
- Conditions
- Osteoporosis, Achlorhydria, GERD, Hip Fracture
- Trial name
- NCT00582972
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison