Clinical trials: Gastroesophageal Reflux
Cough, Gastroesophageal Reflux
Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux
Cough is the most common complaint for which patients seek medical attention in the United States, accounting for approximately 1 billion dollars in health care expenses annually.
- Trial name
- NCT00451841
- Testing
- RTube Exhaled Breath Condensate Collection System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Massachusetts, Worcester
Esophagitis, Reflux
Intravenous vs Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis
The purpose of this study was to compare the pharmacodynamics of intravenous (IV) lansoprazole to oral lansoprazole capsules, once daily (QD), in participants with erosive esophagitis.
- Trial name
- NCT00175045
- Testing
- Lansoprazole
- Volunteers
- 68 people
- Sponsor
- Takeda
Bypass Complication, Obesity
Evaluation of Long-term Adverse Effects of Gastric Bypass in Omega
The omega gastric bypass (OAGB) is developing worldwide as an alternative to the Y gastric bypass (RYGB). Cases of nutrition deficiency after OAGB, in particular protein deficency, are regularly reported in the literature…
- Trial name
- OMEGA10 (NCT04930029)
- Testing
- Ten year evaluation
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Lille
Gastroesophageal Reflux
Randomized Trial for Pharmacogenomics-based Proton Pump Inhibitor Therapy in Children
Proton pump inhibitors are administered to children as off-label use in Japan. The purpose of this study is to evaluate the effects of CYP2C19 genotypes on pharmacokinetic /pharmacodynamic profiles of PPI in children.
- Trial name
- NCT00299845
- Testing
- Lansoprazole
- Where
- Japan
- Sponsor
- Osaka University
Symptomatic Gastroespohageal Reflux Disease
A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD)
Gastroesophageal Reflux Disease (GERD) is a common disorder caused by the reflux of gastric (stomach) acid into the esophagus. The exposure of the lining of the esophagus to the acid will cause damage to the esophagus over time.
- Trial name
- NCT00149851
- Testing
- Tegaserod
- Where
- United States
- Volunteers
- 832 people
- Sponsor
- Novartis
Osteoporosis, Achlorhydria
Does Omeprazole Decrease Intestinal Calcium Absorption?
The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
- Conditions
- Osteoporosis, Achlorhydria, GERD, Hip Fracture
- Trial name
- NCT00582972
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Gastroesophageal Reflux Disease
Evaluation of Upper Esophageal Sphincter Motor Activity in Patients with Extra Esophageal Reflux Symptoms
To evaluate the presence of motor changes of the upper esophageal sphincter detectable by high-resolution manometry in patients with oropharyngeal symptoms referable to extra-esophageal reflux manifestations.
- Trial name
- NCT06773702
- Testing
- gastroenterology and otolaryngological evaluation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Gastroesophageal Reflux Disease, Reflux, Gastroesophageal
A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.
Current treatment for gastroesophageal reflux disease (GERD) confirms an unmet need in patients, based on slow onset of action and an inability to provide 24-hour gastric-acid suppression.
- Trial name
- NCT00405119
- Testing
- AH23844 (lavoltidine), NEXIUM (esomeprazole), ZANTAC (ranitidine)
- Where
- 2 sites in Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
GERD
Efficacy and Saafety of Omez Iin Patients With H.Pylori Associated Diseases
Comparison of efficacy of H.pylori eradication during first line therapy using standard or high doses of omeprazole administered twice daily in combination with amoxicillin and clarithromycin for 10 days.
- Trial name
- Omez-RU2013 (NCT02922699)
- Testing
- OMEZ 40, OMEZ 80
- Volunteers
- 120 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Gastroesophageal Reflux
Treatment Of Gastroesophageal Reflux Disease By Endoscopic Fundoplication, A Placebo-Controlled Study
Aim: To evaluate the therapeutic efficacy of a therapeutic procedure, involving endoscopic suturing, for gastroesophageal reflux disease (GERD) compared to a sham procedure.
- Trial name
- NCT00235677
- Testing
- Endoscopic gastroplication
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- UMC Utrecht
Heartburn
Efficacy and Safety of Itopride vs Placebo in Heartburn
The purpose of this study is to evaluate the effects of itopride in patients with heartburn.
- Trial name
- NCT00382577
- Testing
- Itopride
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Forest Laboratories
Barrett Esophagus, Esophageal Adenocarcinoma
Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's Esophagus
This study compares patients' acceptability and safety of two established endoscopic methods for treating dysplastic Barrett's esophagus: radiofrequency ablation versus hybrid argon plasma coagulation.
- Conditions
- Barrett Esophagus, Esophageal Adenocarcinoma, Reflux Disease
- Trial name
- RATE (NCT05051475)
- Testing
- Endoscopic radiofrequency ablation, Endoscopic hybrid argon plasma coagulation
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Centre of Postgraduate Medical Education
Stomach Neoplasms, Esophageal Neoplasms
Impact of Gastric Tube Reconstruction Widths on Quality of Life for Esophagogastric Cancers
The incidence of cancer of the esophagogastric junction has rapidly risen in recent three decades, and surgery still remains the optimum therapy.
- Trial name
- NCT01911832
- Testing
- esophagojejunostomy after total gastrectomy, Roux-en-Y gastrojejunostomy after subtotal gastrectomy, wide tube reconstruction after subtotal gastrectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Gastroesophageal Reflux Disease
Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
The aim of this study was to evaluate the effect of 14 days treatment with Pantoprazole 40 mg and 20 mg on gastroesophageal reflux disease (GERD) related symptoms in a large patient population.
- Trial name
- PARADE (NCT00829738)
- Testing
- Pantoprazole
- Where
- 717 sites in Germany
- Volunteers
- 4,188 people
- Sponsor
- Nycomed
GERD
A Study to Evaluate the PK, PD and Safety of CKD-382 in Healthy Subjects
to evaluate the pharmacokinetics, pharmacodynamics and safety after single/multiple administration of CKD-382, D860 and D027 in healthy subjects
- Trial name
- NCT05108038
- Testing
- CKD-382, D860, D027
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Gastroesophageal Reflux Disease (GERD)
Post-Market Registry for the Evaluation of RefluxStop in GERD Treatment
This post-market registry aims to assess safety and performance of RefluxStop™ in the treatment of Gastroesophageal Reflux Disease (GERD) in standard of care procedures.
- Trial name
- NCT05870163
- Testing
- RefluxStop implantation, Nissen fundoplication
- Where
- 6 sites in Germany, Italy and 2 more
- Volunteers
- 2,500 people
- Sponsor
- Implantica CE Reflux Ltd.
Pain, Esophageal Sensitivity
Esophageal Hypersensitivity Study in Healthy Volunteers
The purpose of the study is to compare sensitivity and sensitization of visceral pain in the esophagus using different pain stimuli
- Trial name
- NCT00711048
- Testing
- AZD1386
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gastroesophageal Reflux
48 Hours Esophagal pH-monitoring With and Without Gaviscon
At a esophagal pH-monitoring will the classic 24-hour measurement be extended to 48 hours. During the first 24 hours are the measurements without medication.
- Trial name
- NCT02783378
- Testing
- Gaviscon Syrup
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Reflux, Heartburn
Evaluation Study of a Management Strategy for Gastroesophageal Reflux Disease (GERD)
The aim of this project is to compare the GERD clinical outcomes in patients where a structured pathway using the GerdQ questionnaire is implemented compared with the clinical outcomes of those treated without this…
- Conditions
- Reflux, Heartburn, Regurgitation, Esophagitis
- Trial name
- NCT00842387
- Where
- 66 sites in Austria, Italy and 3 more
- Volunteers
- 2,370 people
- Sponsor
- AstraZeneca
Vesicoureteral Reflux
Determination of Voiding Patterns of Children With Vesicoureteral Reflux
Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.
- Trial name
- NCT00186199
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.