Clinical trials: Gastrointestinal Bleed
GI-bleeding
Emergency Capsule Endoscopy in Severe GI-bleeding
Primary objective: Evaluation of capsule endoscopy in the emergency setting of severe GI-Bleeding.
- Trial name
- NCT01584869
- Testing
- capsule endoscopy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Bleeding Peptic Ulcer
Multicenter Validation on Predicting Mortality for Patients With Bleeding Peptic Ulcers
This study aimed to validate CU prediction model on mortality for patients with high risk bleeding peptic ulcers after therapeutic endoscopy.
- Trial name
- NCT02245802
- Where
- China
- Volunteers
- 785 people
- Sponsor
- Chinese University of Hong Kong
Cirrhosis, Liver, Coagulopathy
Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis
The goal of this clinical trial is to compare resuscitation strategies in patients with cirrhosis and gastrointestinal bleeding.
- Conditions
- Cirrhosis, Liver, Coagulopathy, GastroIntestinal Bleeding
- Trial name
- STRATEGIC (NCT05583539)
- Testing
- Thromboelastography
- Sponsor
- Vanderbilt University Medical Center
Upper Gastrointestinal Bleeding
A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01275937
- Testing
- Esomeprazole
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Taipei Medical University
Hemorrhage
Endoscopy for Bleeding Situations in Surgical Patients
Retrospective analysis of surgical patients with relevant gastrointestinal bleeding situations and indication for endoscopy for bleeding
- Trial name
- NCT04523753
- Testing
- emergency endoscopy
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Traumatic Brain Injury, Subarachnoid Hemorrhage
NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
This is an observational study in neurocritical care units at University of California San Francisco Medical Center (UCSFMC), Zuckerberg San Francisco General Hospital (ZSFGH), UC Davis, and Emory University.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure
- Trial name
- NOVEL ICP (NCT04548596)
- Testing
- Transcranial Doppler
- Where
- 3 sites in United States
- Volunteers
- 162 people
- Sponsor
- Emory University
Non-variceal Upper Gastrointestinal Bleeding, Gastrointestinal Ulcer
European Survey of Non-Variceal Upper Gastro Intestinal Bleeding (NVUGIB)
The aim of this study is to assess the current management strategies in a pan-European "real-life" setting to uncover the unmet need in this area: non-variceal gastrointestinal bleedings.
- Conditions
- Non-variceal Upper Gastrointestinal Bleeding, Gastrointestinal Ulcer, Gastrointestinal Hemorrhage
- Trial name
- ENERGIB (NCT00797641)
- Where
- 97 sites in Belgium, Greece and 5 more
- Volunteers
- 2,500 people
- Sponsor
- AstraZeneca
Advanced Heart Failure, Left Ventricular Assist Devices
Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients
The TARGET trial is a prospective, single-center, randomized, open-label, active-controlled inequality clinical trial designed to evaluate the safety and efficacy of low-intensity anticoagulation therapy (target INR 1.5-2.0)…
- Conditions
- Advanced Heart Failure, Left Ventricular Assist Devices, Anticoagulation Treatment, Bleeding Complications
- Trial name
- TARGET (NCT07081035)
- Testing
- Warfarin (low-intensity anticoagulation), Warfarin (standard anticoagulation)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center
Fetal Membranes, Premature Rupture, Premature Birth
The Use of Cranberries in Women With Preterm Premature Rupture of Membranes
Cranberries have been proved to reduce the rate of urinary tract infections in a population of women with recurrent urinary tract infections in previous studies.
- Trial name
- NCT00247104
- Testing
- Cranberries - Vaccinium macrocarpon
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hemorrhoid, Hemorrhoid Bleeding
Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment
BRIGHT is a Europe-wide study that will follow up to 250 adults with bleeding symptoms from haemmorhoids (Grade II-III categories).
- Trial name
- BRIGHT (NCT07264413)
- Testing
- Haemorrhoid artery embolizsation (HAE)
- Volunteers
- 250 people
- Sponsor
- Cardiovascular and Interventional Radiological Society of Europe
End Stage Liver DIsease, Liver Transplant; Complications
Fibrinogen and Intraoperative Bleeding in Liver Transplant
Liver transplantation is the only treatment for end-stage liver disease. It is a high-risk surgery that can cause heavy intraoperative bleeding.
- Trial name
- FIB_TOF (NCT04925843)
- Where
- Canada
- Volunteers
- 612 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
H Pylori Infection
Prevalence of Asymptomatic H Pylori Infection Among Patients Undergoing PCI and Impact of Its Eradication on Occurrence of GIT Symptoms and Bleeding"
In the present study, the aim was to report the prevalence of positive H. pylori infection in an unselected population referred for coronary intervention and likely to required DAPT or DPI, also the study assessed impact of H.
- Trial name
- NCT07487142
- Testing
- BISMUTH TETRACYCLINE METRONIDAZOLE OMEPRAZOLE
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Beni-Suef University
Upper GI Bleeding
Validation of Prognostic Accuracy of ABC ( Age, Blood Urea Nitrogen , Co-morbidities ) and Horibe Pre-endoscopy Scoring Systems in Patients With Upper Gastrointestinal Bleeding in Sohag University Hospital .
Upper gastrointestinal bleeding (UGIB) is a common medical emergency with significant morbidity and mortality. Treating physicians are urged to perform rapid diagnosis, careful risk assessment, and effective resuscitation to…
- Trial name
- NCT05876741
- Testing
- history taking , vital signs and labaratory investigations
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Gastrointestinal Bleeding
Yiwei Jiaohuang Ointment for Gastrointestinal Bleeding Associated With Oral Antithrombotic Agents
The goal of this clinical trial is to evaluate the clinical efficacy and safety of YiWei Jiaohuang Ointment in treating gastrointestinal bleeding associated with oral antithrombotic therapy.
- Trial name
- NCT07339956
- Testing
- A Chinese herb formula--Yiwei Jiaohuang Onitment, Rabeprazole Enteric-Coated Tablets
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Hepatocellular Carcinoma, Esophageal Varix
Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC
The goal of this study is to evaluate whether prophylactic endoscopic variceal ligation (EVL) can prevent esophageal variceal bleeding in patients with hepatocellular carcinoma (HCC) receiving atezolizumab and bevacizumab…
- Conditions
- Hepatocellular Carcinoma, Esophageal Varix, Bleeding Esophageal Varices
- Trial name
- ESCOAT (NCT06819566)
- Testing
- Endoscopic variceal ligation (EVL)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center
Occult Gastrointestinal Bleeding
Performance Value of Research of Occult Gastrointestinal Bleeding by Immunoassay in the Diagnostic Process of Iron Deficiency Anemia in Patients Over 75 Years
This study aims to characterize the diagnostic performance of immunological testing of occult gastrointestinal bleeding in stool in the population aged over 75 years with iron deficiency anemia.
- Trial name
- STRATAGANEMIE (NCT02727075)
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastrointestinal Hemorrhage
Assessment of Combined Bowel Preparation for Capsule Endoscopy Study
The investigators are conducting a study to see if taking a bowel preparation before having a capsule endoscopy is more helpful than the standard preparation of not eating after 7 PM the night before a capsule endoscopy in making…
- Trial name
- CEPREP (NCT01243736)
- Testing
- Combination Prep
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Peptic Ulcer Bleeding, Hypoalbuminemia
The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia
To test whether intravenous albumin can decrease the rebleeding rate or shorten the duration of hospitalization in patients with peptic ulcer bleeding and hypoalbuminemia.
- Trial name
- NCT01822600
- Testing
- Human albumin, Omeprazole
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Cheng-Kung University Hospital
Benign Neoplasm of Stomach, Malignant Neoplasm of Stomach
Surgicel® Fibrillar for Delayed Bleeding After ESD
The aim of this study is to assess the effect of Surgicel® Fibrillar as adjuvant treatment to H2RA on preventing ulcer bleeding after ESD for gastric epithelial tumors
- Trial name
- NCT01758965
- Testing
- PPI, H2RA and surgicel
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Soonchunhyang University Hospital
Cirrhosis, Liver, Upper Gastrointestinal Bleeding
Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding
The investigators studied the renal function index level in terlipressin treated cirrhotic patients with upper-gastrointestinal bleeding at different time point.
- Trial name
- NCT04358016
- Testing
- Terlipressin, Somatostatin
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Changhai Hospital