Clinical trials: Gastrointestinal Disorders, Functional
Gastrointestinal Disorder Postoperative
Gum Chewing and Postoperative Intestinal Function After Gynecolgic Operations
The investigators aimed to assess whether postoperative gum chewing improve intestinal functions.
- Trial name
- NCT02455739
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Aging, Hyperthermia
Aging and Gastrointestinal Barrier Function
The purpose of this study is to assess the gastrointestinal responses of the elderly and younger populations during hyperthermia.
- Trial name
- NCT05816551
- Testing
- Hyperthermia Trial, Control Trial
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Functional Dyspepsia, Diabetic Gastroparesis
Assessment of Gastro-Intestinal Function to a Mixed Meal by Non-invasive Imaging
Dyspeptic symptoms, such as pain after eating, bloating and nausea all have major impact on quality of life and health care costs. When no structural cause is identified, patients are diagnosed with functional dyspepsia.
- Trial name
- NCT01919021
- Testing
- Magnetic Resonance Imaging MRI, Gamma Scintigraphy, Assessment of Gastric motor and sensory function
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Irritable Bowel Syndrome
Efficacy of a Probiotic Blend to Reduce Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a recurrent, functional disorder characterized by abdominal pain and discomfort, changes in bowel habits and gastrointestinal symptoms such as distension and sensation of abdominal inflammation…
- Trial name
- NCT05819281
- Testing
- Probiotic blend
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Inulin, IBS (Irritable Bowel Syndrome)
The Effect of Inulin Supplementation in Individuals With IBS-C
Background: This study aimed to evaluate the effects of inulin supplementation on nutritional intake, anthropometric parameters, and bowel symptoms in individuals diagnosed with IBS-C.
- Conditions
- Inulin, IBS (Irritable Bowel Syndrome), Nutritional Status, Anthropometric Measurement
- Trial name
- NCT06945302
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Functional Colonic Disease, Fecal Incontinence
Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility
The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.
- Trial name
- NCT00213317
- Testing
- lombo-sacral magnetic stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome
Targeted Food Elimination for Treatment of Functional Gastrointestinal Diseases in Children
Recurrent Abdominal Pain (RAP) in children is common and causes significant functional impairment and poor quality of life. Lifestyle factors such as diet, anxiety, and stress are important triggers of abdominal pains, but there…
- Conditions
- Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome, Abdominal Pain (AP)
- Trial name
- FGID (NCT02565355)
- Testing
- Dietary Exclusion, Standard Treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Aging, Inspiratory Muscle Weakness
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of a 4-week inspiratory muscle training (IMT) program on diaphragm muscle thickness, fatty liver density, functional capacity, and quality of life in elderly men…
- Conditions
- Aging, Inspiratory Muscle Weakness, Fatty Liver, Reduced Functional Capacity
- Trial name
- IMT AND ELDERL (NCT07193082)
- Testing
- Experimental Inspiratory Muscle Training (IMT Group), Control Group: No inspiratory muscle training.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Irritable Bowel Syndrome
Predictive Factors for a Clinical Diagnosis of Irritable Bowel Syndrome in a Large Cohort of Young Adults.
The prevalence of IBS in the community has been reported in numerous cross-sectional surveys. However, less is known about the incidence of IBS ,mainly due to its slow development and to patients under-reporting.
- Trial name
- NCT01854060
- Where
- Israel
- Volunteers
- 440,822 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Cystic Fibrosis
Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis
OBJECTIVES: I. Determine the effect of different doses of ibuprofen on neutrophil (polymorphonuclear leukocyte; PMN) delivery to a mucosal surface (the oral mucosa) in patients with cystic fibrosis and healthy controls. II.
- Trial name
- NCT00004440
- Testing
- ibuprofen
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- FDA Office of Orphan Products Development
Hepatic Insufficiency
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function
The purpose of this study is to measure the effect of HI on the PK, safety, and tolerability of a single dose of mavorixafor compared to matched healthy volunteers (HVs) with normal hepatic function.
- Trial name
- NCT06858696
- Testing
- Mavorixafor
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- X4 Pharmaceuticals
Fecal Incontinence
Anal Motor Function in Fecal Incontinence
Traditionnal measurment of anorectal function is perfomed with manometric device using 2 to 3 pressure sensors. The investigators aim to evaluate the usefulness of high resolution manometry to measure anorectal motility
- Trial name
- NCT01786317
- Testing
- High resolution manometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
The Comparison Between the Biomarkers in Inflammatory Bowel Disease Patients and General Control Group
The aims of this study is to investigate a blood-based biomarker that can replace endoscopy in patients with inflammatory bowel disease.
- Trial name
- NCT03778918
- Testing
- inflammatory bowel disease, IBS or Normal Control
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Cold, Cold Symptom
Ability of Beta-glucan Supplementation to Augment Immune Function
This proposed study is designed to assess the efficacy of a capsule containing beta-glucan taken orally daily as compared to a placebo capsule on the URTI symptoms, and the immune response change in marathon runners
- Conditions
- Cold, Cold Symptom, Flu, Flu Symptom
- Trial name
- NCT03769012
- Testing
- Beta-Glucan
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Cardiometabolic Health, Gastro-intestinal Wellbeing
Effects of Wholegrains on Children's Health (KORN)
KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.
- Conditions
- Cardiometabolic Health, Gastro-intestinal Wellbeing, Cognitive Function, Overweight
- Trial name
- NCT04430465
- Testing
- Grain products high in wholegrains from oat and rye, Grain products low in wholegrains
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cervix Neoplasms, Endometrial Cancer
Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function
Postoperative ileus (POI) is a transient loss of coordinated peristalsis precipitated by surgery and exacerbated by opioid pain medication.So,how to provide patients with ideal analgesia without affecting the recovery of…
- Conditions
- Cervix Neoplasms, Endometrial Cancer, Adenomyosis, Fibroid Uterus
- Trial name
- NCT04295109
- Testing
- the drug of intravenous patient-controlled analgesia
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Irritable Bowel Syndrome
Effect of Menstrual Cycle on Central Nervous System (CNS) Processing of Gut Stimuli in Irritable Bowel Syndrome (IBS) and Control
The hypothesis of the study is that women perceive intestinal stimulation (rectal balloon distention) differently in different phases of the menstrual cycle, i.e there is an effect of hormones on the sensory pathway, and that…
- Trial name
- NCT00219531
- Testing
- perception of rectal balloon distention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Irritable Bowel Syndrome
The Effect of Zespri Green Kiwifruit on Digestive and Gut Health Functions
The proposed study will primarily demonstrate the efficacy of kiwifruit as a food intervention for the relief of constipation and associated symptoms in functionally constipated adults, and those with IBS-C.
- Trial name
- NCT02888392
- Testing
- Kiwifruit, Psyllium
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zespri International Limited
Swallowing Disorder, Dysphagia
Functional Response Characteristics of Brain Under Swallowing Task Paradigm
Functional near-infrared spectroscopy was used to investigate the cortical activation patterns and lateralization during swallowing tasks in 15 healthy middle-aged and elderly people and 15 healthy young people.
- Conditions
- Swallowing Disorder, Dysphagia, Swallowing Substances
- Trial name
- NCT06411236
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ruyao Liu