Clinical trials: Gastrointestinal Neoplasm
Uterine Cervical Neoplasm, Dietary Modification
Effect of a Low Residue Diet in Comparison to the Dietetic Recommendations From the INCan in Cervical Cancer Patients
In Mexico, cervical cancer (CC) ranks second in incidence and mortality among women. The National Institute of Cancer in Mexico (lNCan) receives annually about 500 patients with CC, 80% of which are diagnosed with locally…
- Conditions
- Uterine Cervical Neoplasm, Dietary Modification, Radiation Toxicity, Gastrointestinal Complication
- Trial name
- NCT03100409
- Testing
- Dietary modification
- Where
- Mexico
- Volunteers
- 137 people
- Sponsor
- National Institute of Cancerología
HepatoCellular Carcinoma
Phase II Study of HAIC Using Cisplatin,Leucovorin and 5-Fluorouracil
The purpose of this phase II study is to determine the recommended dose, as well as the safety and efficacy of the combination of oxaliplatin, leucovorin and 5-Fu introduced by hepatic arterial infusion chemotherapy (HAIC) in…
- Trial name
- NCT02987699
- Testing
- 5-Fu, oxaliplatin , leucovorin
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Sun Yat-sen University
Colorectal Cancer
Metabolomics-Based Detection of Colorectal Cancer
The purpose of this study is to collect specimens to perform metabolic profiling of serum and urine from patients with colorectal cancer, colon polyps and healthy patients.
- Trial name
- metabolomics (NCT00507598)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Indiana University
Unresectable Locally Advanced Cancer, Metastatic Pancreatic Cancer
Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic Cancer
Adapted Physical Activity (APA) program may provide an opportunity to improve symptoms for patients with unresectable pancreatic cancer.
- Trial name
- NCT02184663
- Testing
- without APA program, APA program
- Where
- 17 sites in France
- Volunteers
- 313 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Hepato Cellular Carcinoma (HCC)
Fibroscan Evaluating Immunotherapy Response in Hepatocellular Carcinoma
The goal of this prospective cohort study is to evaluate the role of transient elastography (Fibroscan) in predicting the response of immunotherapy in advanced Hepatocellular carcinoma (HCC) patients.
- Trial name
- NCT06960863
- Testing
- fibroscan
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Colorectal Cancer, Polyps
Vitamin D/Calcium Polyp Prevention Study
Extensive experimental and observational data suggest that intake of calcium and of vitamin D exert protective effects on colorectal neoplasia.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00153816
- Testing
- Calcium Carbonate, Vitamin D3
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 2,813 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Palliative Care, Cancer Liver
Early Palliative Care Integration in Interventional Cancer Care
A mixed methods randomized control trial assessing the impact of early palliative care incorporation in liver cancer and metastatic colorectal cancer on caregiver well-being, patient physical and psychosocial outcomes, and health…
- Conditions
- Palliative Care, Cancer Liver, Cancer Colon
- Trial name
- EPIICC (NCT03185416)
- Testing
- Palliative Care Training
- Sponsor
- University of Miami
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer
This phase I trial is studying the side effects and best dose of erlotinib hydrochloride when given together with cetuximab and to see how well they work in treating patients with advanced gastrointestinal cancer, head and neck…
- Conditions
- Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Advanced Adult Primary Liver Cancer, Carcinoma of the Appendix
- Trial name
- NCT00397384
- Testing
- cetuximab, erlotinib hydrochloride, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Cancer Institute (NCI)
Rectal Cancer
Efficacy and Safety Study of Neoadjuvant in Treating Patients With Resectable Local Recurrent Rectal Cancer
RATIONALE: Surgical resection and adjuvant therapy has become the main treatment for resectable local recurrent rectal cancer. However the efficacy and safety of adjuvant therapy is still unknown.
- Trial name
- NARC (NCT01271192)
- Testing
- surgical resection and adjuvant therapy, Neoadjuvant followed by operation
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Sun Yat-sen University
Colorectal Neoplasms
Pharmacogenomics Blood Sampling Protocol For Irinotecan/Fluorouracil/Leucovorin(CPT-11/FU/LV).
This protocol describes procedures for the collection of blood samples for the intent of determining genetic contribution to the safety and efficacy of CPT/FU/LV.
- Trial name
- NCT00140036
- Testing
- Blood draw
- Where
- 34 sites in United States, Canada
- Volunteers
- 137 people
- Sponsor
- Pfizer
Carcinoma, Hepatocellular
Nexavar Post-marketing Surveillance for Hepatocellular Carcinoma in Japan
This study is a regulatory post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Nexavar for unresectable hepatocellular carcinoma (HCC).
- Trial name
- NCT01411436
- Testing
- Sorafenib (Nexavar, BAY43-9006)
- Where
- Japan
- Volunteers
- 1,637 people
- Sponsor
- Bayer
Gastric Cancer
Laparoscopy-assisted Total Gastrectomy for Clinical Stage I Gastric Cancer (KLASS-03)
The purpose of this study is to evaluate the safety and feasibility of laparoscopy-assisted total gastrectomy for early upper gastric cancer compared with open total gastrectomy.
- Trial name
- KLASS-03 (NCT01584336)
- Testing
- LATG
- Where
- 10 sites in South Korea
- Volunteers
- 168 people
- Sponsor
- Soonchunhyang University Hospital
Pancreas Neoplasm
Usefulness of 3D Digital Reconstruction in the Imaging Diagnosis of Pancreatic Tumors
Reconstruction using 3D virtual models has brought about a revolution in diagnostic imaging and its use is increasingly widespread.
- Trial name
- NCT04783844
- Testing
- Virtual modelization.
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Germ Cell Tumors, Hepatic Cancer
Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy
Life-threatening thrombocytopenia (low platelet count) and neutropenia (low white blood count) remain the major dose-limiting toxicities following chemotherapy treatment for cancer.
- Conditions
- Germ Cell Tumors, Hepatic Cancer, Neuroblastoma, Osteosarcoma
- Trial name
- NCT00187109
- Testing
- Recombinant Human Thrombopoietin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Jude Children's Research Hospital
Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
This phase I/II trial studies the safety, side effects and best dose of M3814 and to see how well it works when given together with radiation therapy in treating patients with pancreatic cancer that has spread to nearby tissue or…
- Trial name
- NCT04172532
- Testing
- Biopsy Procedure, Biospecimen Collection, Computed Tomography
- Where
- 44 sites in United States
- Volunteers
- 92 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Study of Oxaliplatin, Capecitabine and Bevacizumab as First Line Treatment for Patients With Advanced Colorectal Cancer
This study is for people with colorectal cancer, who have tumors that cannot be completely removed by surgery. This study is being done to find out how long it takes tumors to grow after patients receive the drugs capecitabine…
- Trial name
- NCT00159432
- Testing
- Oxaliplatin, Bevacizumab, Capecitabine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Southern California
Esophageal Cancer, Gastric Cancer
Endoscopic Ultrasound in Diagnosing Cancer in Patients With Localized Stomach Cancer or Esophageal Cancer
RATIONALE: Diagnostic procedures, such as endoscopic ultrasound, may help doctors learn the extent of stomach cancer or esophageal cancer.
- Trial name
- NCT00629863
- Testing
- cisplatin, fluorouracil, questionnaire administration
- Where
- 9 sites in United Kingdom
- Volunteers
- 700 people
- Sponsor
- North Wales Organisation for Randomised Trials in Health
Cancer Diagnosis, LungCancer
Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing
The goal of this observational study is to screen and differentiate common cancers in participants with or without suspicious lesions.
- Conditions
- Cancer Diagnosis, LungCancer, Gastric Cancer, Liver Cancer
- Trial name
- NCT06036563
- Where
- 8 sites in China
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
SNP-Based Prediction of Oral Mucositis Risk in Patients Receiving Hematopoietic Stem Cell Transplants (HSCT)
The goal of this study is to gain new knowledge about genetic risk factors thta may affect the development of mucositis, the chemotherapy-induced sores in the mouth and esophagus following HSCT.
- Conditions
- Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma
- Trial name
- NCT01402687
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Dana-Farber Cancer Institute
Unresectable Colorectal Liver Metastases
Local Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases
The main objective of this trial is to determine feasibility and tolerance of the human body to RFA associated with local immunomodulation carried out using a thermoreversible hydrogel combined with 2 immunomodulators, GMCSF and…
- Trial name
- LICoRN-01 (NCT04062721)
- Testing
- Chemotherapy, Radiofrequency ablation (RFA), In situ immunotherapy
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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