Clinical trials: Gastrointestinal Subepithelial Tumors
Upper Gastrointestinal Subepithelial Tumors
Biopsy Protocol of Upper Gastrointestinal Subepithelial Tumors:Diagnostic Accuracy of EUS-FNB Versus Unroofing Biopsy
To increase the diagnostic accuracy of subepithelial tumors, larger tissue samples are required. It is difficult to obtain adequate tissue samples. There were several biopsy methods to obtain tissue samples.
- Trial name
- NCT02646241
- Testing
- unroofing biopsy, EUS-FNB(endoscopic ultrasonography guided fine needle biopsy)
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Yonsei University
Gastrointestinal Stromal Cell Tumors, Foregut Subepithelial Lesions
Prospective Database of Gastrointestinal Stromal Cell Tumors (GISTs)
Specific Aim 1: To determine patient compliance with a GIST surveillance program Hypothesis: Patient compliance with a GIST surveillance program will be low.
- Trial name
- NCT02147145
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Washington University School of Medicine
Gastrointestinal Subepithelial Tumors
Anxiety and Fear of Cancer Before and After Banding Without Resection in Small SET Management (QUALI-BANDING-SET)
To analyze the hypothetical improvement in anxiety degree, quality of life and fear of cancer in patients diagnosed with a small gastrointestinal subeptithelial tumor when opting for the removal of the lesion.
- Trial name
- NCT04316000
- Testing
- Initial Anxiety and Fear of Cancer Test, Endoscopic band ligation without resection of the subpetihelial tumour., 1-2 Months Anxiety and Fear of Cancer Test
- Where
- 7 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Francesc Bas-Cutrina
Gastrointestinal Subepithelial Tumors
Banding Without Resection in Small Subepithelial Tumours
To analyse the effectiveness and safety of endoscopic band ligation without resection in small gastrointestinal subepithelial tumours.
- Trial name
- BANDING-SET (NCT03247231)
- Testing
- Endoscopic band ligation without resection, SINK
- Where
- 7 sites in Spain
- Volunteers
- 157 people
- Sponsor
- Joan B Gornals
Gastrointestinal Subepithelial Tumors
EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors
Background: Preoperative pathologic diagnosis of subepithelial tumor (SET) can improve clinical decision making. Although EUS-guided fine needle aspiration (FNA) is currently considered the standard method for sampling SET, its…
- Trial name
- NCT02943837
- Testing
- Device: 22G FNA needle, Device: 20G FNB needle
- Sponsor
- Asan Medical Center
Gastrointestinal Tract, Gastrointestinal Stromal Tumor
Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors
The exact incidence of subepithelial tumors (SETs) in the gastrointestinal (GI) tract is unknown, but the prevalence of gastric SETs detected during routine esophagogastroduodenoscopy is 0.36%.
- Trial name
- NCT02884154
- Testing
- Echotip ProCoreⓇ HD Ultrasound Biopsy Needle
- Volunteers
- 39 people
- Sponsor
- Pusan National University Hospital
Subepithelial Tumors of the Upper Gastrointestinal Tract
Role of Doppler Endoscopic Probe in the Diagnosis of Subepithelial Gastrointestinal Lesions.
RESEARCH PLAN I-TITLE Role of Doppler endoscopic probe in the diagnosis of subepithelial gastrointestinal lesions. II-BACKGROUND Subepithelial lesions (SEL) are commonly encountered during routine endoscopies with an estimated…
- Trial name
- DopplerSEL (NCT05983406)
- Testing
- Doppler investigation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Francisco Baldaque-Silva
Subepithelial Tumors of the Upper Gastrointestinal Tract
22-G-Procore Needle for the Diagnosis of SETs of the Upper GI Tract
The goal of this prospective study is to evaluate the feasibility of the 22-G Core Biopsy Needle with reverse bevel (Procore TM) in biopsy sampling of subepithelial tumors of the upper gastrointestinal tract.
- Trial name
- PRO-SET (NCT01726010)
- Testing
- 22-G Procore Needle
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Leiomyoma, GIST
Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions
Gastrointestinal stromal tumors (GIST) are the most common malignant subepithelial lesions (SELs) found in the gastrointestinal tract.
- Trial name
- NCT05474794
- Testing
- DFI-EUS, CE-EUS
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Disorder of Upper Gastrointestinal Tract, Gastrointestinal Stromal Tumors
EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs
Sub epithelial lesions (SELs) of the gastrointestinal (GI) tract are commonly identified during routine endoscopy. Most of these lesions are benign.
- Conditions
- Disorder of Upper Gastrointestinal Tract, Gastrointestinal Stromal Tumors, Gastrointestinal Neoplasms
- Trial name
- NCT02866045
- Testing
- EUS-guided fine needle biopsy, Single incision needle knife biopsy
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Unity Health Toronto
Subepithelial Gastrointestinal Tumors
SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS
This will be a longitudinal, prospective, observational multicenter study where the role of EUS-E will be examined in differentiating subepithelial gastrointestinal tumors in 138 patients
- Trial name
- SunnyDay021 (NCT06324032)
- Testing
- EUS Elastography (EUS-E)
- Where
- 7 sites in Italy
- Volunteers
- 138 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Submucosal Tumor of Gastrointestinal Tract
Diagnostic Accuracy of SurePath™ in EUS-FNA
It is a prospective randomized controlled study to evaluate the diagnostic accuracy of SurePath™ liquid-based cytology in endoscopic ultrasound-guided sampling.
- Trial name
- NCT05394129
- Testing
- SurePath™
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Seoul National University Hospital
Esophageal Subepithelial Lesions
EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
This is a single-blinded randomized control trial trying to compare the effectiveness of diagnosis between two techniques employed in tissue sampling for subepithelial tumors (SETs) of the gastrointestinal tract.
- Trial name
- NCT02282111
- Testing
- 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Gastrointestinal Stromal Tumors, Gastric Subepithelial Tumors
Development of a Multimodal AI System for GIST Management
Background: Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Accurate pre-operative diagnosis, risk stratification, and genotyping are critical for determining the…
- Conditions
- Gastrointestinal Stromal Tumors, Gastric Subepithelial Tumors, Gastric Leiomyoma, Artificial Intelligence (AI)
- Trial name
- NCT07454967
- Testing
- Multimodal AI Analysis System
- Where
- 9 sites in China
- Volunteers
- 300 people
- Sponsor
- Qun Zhao
Gastric Subepithelial Tumor
Novel Endoscopic Resection of Upper Gastrointestinal Subepithelial Tumors Originating From the Muscularis Propria
Endoscopic submucosal tumor resection using biopsy forceps was performed for 11 consecutive patients who had clinical indications for lesion removal.
- Trial name
- NCT03037034
- Testing
- Forcep
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Korea University Anam Hospital
Gastrointestinal Subepithelial Tumors
EUS-Elastography and Contrast-Enhanced EUS Diagnostic Accuracy in the Differential Diagnosis of Subepithelial Gastrointestinal Tumors
The differentiation among the Gastrointestinal Subepithelial Tumors (SETs) represents a clinical challenge. Endoscopic Ultrasound (EUS) alone may be ineffective in differentiating SETs subtypes, and tissue sampling of these…
- Trial name
- SUNNYDAY (NCT04695262)
- Testing
- EUS-FNB
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
Mediastinal ( Chest) Masses, Gastrointestinal Subepithelial Tumors
Role of Endoscopic Ultrasound Elastography in Diagnosis of Gastrointestinal Subepithelial and Mediastinal Lesions
The aim of this study is to evaluate the role of endoscopic ultrasound (EUS) in the diagnosis of mediastinal and gastrointestinal subepithelial lesions.
- Trial name
- NCT07419191
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Gastrointestinal Subepithelial Tumors
The Prospective Study on the Effect of Ilaprazole in Non-erosive Reflux Disease Patients; Focused on Histologic Findings and Inflammatory Biomarker
Non-erosive reflux disease (NERD) patients used to be less responsive to proton pump inhibitor (PPI)s as compared with patients with erosive esophagitis.
- Trial name
- NCT02666976
- Testing
- Ilaprazole
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Subepithelial Gastrointestinal Tumors, Adenoma
Gastroduodenal Full Thickness Resection Device Registry - gdFTRD® Registry
Endoscopic full-thickness resection (EFTR) is a therapeutic option for the treatment of challenging lesions such as subepithelial tumors (SETs) and epithelial neoplasia extending deeper than the mucosa or associated with…
- Trial name
- NCT07142902
- Testing
- Data processing only, treatment is not part of the registry
- Where
- 3 sites in Germany
- Volunteers
- 306 people
- Sponsor
- Ovesco Endoscopy AG
Gastric Neoplasms, Gastrointestinal Stromal Tumors
Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST)
Prospective observational trial. A full thickness resection of gastric subepithelial tumors is performed after application of full thickness sutures underneath the tumor with the GERDX(TM) device.
- Trial name
- NCT02488746
- Testing
- GERDX(TM)
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Kliniken Ludwigsburg-Bietigheim gGmbH