Clinical trials: Gastrointestinal Surgery
Post-induction Hypotension (PIH), Gastrointestinal Tumor Surgery
Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery
This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid…
- Trial name
- NCT07777159
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Ankara City Hospital Bilkent
Abdominal Massage, Enteral Nutrition
Effect of Abdominal Massage on Gastrointestinal Symptoms After Head and Neck Cancer Surgery
This study aimed to evaluate whether abdominal massage could reduce abdominal pain, constipation, and gas/bloating in patients receiving enteral nutrition through a nasogastric tube after surgery for head and neck cancer.
- Conditions
- Abdominal Massage, Enteral Nutrition, Nasogastric Feeding, Head and Neck Surgery
- Trial name
- HNC-AM (NCT07889011)
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Maltepe University
Early-stage Upper Gastrointestinal Cancer, Stomach Cancer, Adenocarcinoma
Clinical Study on Using Laparoscopic Sentinel Lymph Node Navigation Combined With Dual Endoscopy Surgery for Early Gastric Cancer
Gastric cancer is a common malignant tumour worldwide, and in China, the incidence and mortality rates of gastric cancer remain high.
- Conditions
- Early-stage Upper Gastrointestinal Cancer, Stomach Cancer, Adenocarcinoma, Laparoscopy-assisted Surgery, Endoscope
- Trial name
- NCT07708012
- Testing
- Combined double-scope surgery
- Where
- 2 sites in China
- Volunteers
- 9 people
- Sponsor
- wangdongsheng
Surgery of Upper Gastrointestinal Tract Cancer
Prehabilitation for Upper Gastrointestinal Tract Cancer Surgery
Patients receiving surgery of upper gastrointestinal tract are often elderly, frail, malnourished, with poor functional reserve. They are associated with poor post-operative outcomes.
- Trial name
- NCT07713888
- Testing
- Prehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taichung Tzu Chi Hospital
Type 2 Diabetes Mellitus (DM), Gastrointestinal Surgery
Preoperative Oral Carbohydrate Loading in Patients With Type 2 Diabetes Undergoing Gastrointestinal Surgery
This study is a single-center randomized controlled trial in adults with type 2 diabetes who are scheduled for elective gastrointestinal surgery.
- Trial name
- NCT07830537
- Testing
- Standard ERAS Fasting and Clear-Fluid Management, Oral Carbohydrate Loading, Intravenous Glucose
- Volunteers
- 126 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Post Abdominal Surgery, Gastrointestinal Motility Disorder
Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility
Postoperative bowel motility is an important indicator of recovery after abdominal surgery and may be influenced by preoperative nutritional status.
- Conditions
- Post Abdominal Surgery, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- NCT07808281
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bahçeşehir University
Hypoxemia During Surgery, Gastrointestinal Endoscopy
Respiratory Safety of Oliceridine During Sedated Gastrointestinal Endoscopy
This study is a prospective, single-center, double-blind, randomized controlled trial designed to evaluate the effect of oliceridine versus sufentanil on the incidence of hypoxemia in adult patients undergoing gastrointestinal…
- Trial name
- NCT07187765
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Shiyou Wei
Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome
Development and Validation of a Risk Prediction Model for Cardiac Surgery-associated Acute Kidney Injury Based on the Gut-Kidney Axis, Incorporating Gut Microbiota and Their Metabolites
This is a single-center prospective observational cohort study enrolling adult patients scheduled for cardiac surgery. Multi-timepoint clinical indicators, stool samples for gut microbiota and metabolomics profiling and artery…
- Conditions
- Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome, Metabolome, Risk Assessment
- Trial name
- NCT07738796
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peking Union Medical College Hospital
Upper Gastrointestinal Laparoscopic Surgery
A Study at Multiple Centers to Evaluate the Safety and Practicality of the Levita Magnetic Surgical System for Use in Laparoscopic Upper Gastrointestinal Surgeries.
A Study at Multiple Centers to Evaluate the Safety and Practicality of the Levita Magnetic Surgical System for Use in Laparoscopic Upper Gastrointestinal Surgeries.
- Trial name
- NCT07293611
- Testing
- Levita Magnetic Surgical System
- Where
- 2 sites in Chile
- Volunteers
- 30 people
- Sponsor
- Levita Magnetics
Postoperative Gastric Distension, Postoperative Gastrointestinal Dysfunction
Anti-Bloating Patch for Postoperative Gastric Distension After Cardiac Surgery
Postoperative gastric distension is a common gastrointestinal complication after cardiac surgery and may delay recovery, prolong intensive care unit (ICU) stay, and reduce patient comfort.
- Conditions
- Postoperative Gastric Distension, Postoperative Gastrointestinal Dysfunction, Cardiac Surgery
- Trial name
- ABP-CS (NCT07677423)
- Testing
- Anti-Bloating Patch, Standard Perioperative Care
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Southeast University, China
Surgery, Colorectal Cancer
Postoperative Electrical Muscle Stimulation Two
Undesirable loss of skeletal muscle mass (atrophy) is a common feature of many diseases as well as ageing, bed rest and physical inactivity.
- Conditions
- Surgery, Colorectal Cancer, Muscle Atrophy, Cancer Gi
- Trial name
- POEMS2 (NCT06964438)
- Testing
- Neuromuscular Electrical Stimulation, Protein supplement drink
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Nottingham
Obesity, Morbid, Bariatric Surgery
Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity…
- Conditions
- Obesity, Morbid, Bariatric Surgery, Intestinal Permeability, Gastrointestinal Symptoms
- Trial name
- METABAR (NCT07643376)
- Testing
- Clinical and Biochemical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University
Rectal Cancer Surgery, Randomized Clinical Trial
Drainage After Rectal Excision for Rectal Cancer
After rectal excision, the rate of anastomotic leak and abscess is higher than after colic surgery. In order to limit and avoid the risk of pelvic sepsis after rectal excision, a prophylactic pelvic drainage is usually used.
- Conditions
- Rectal Cancer Surgery, Randomized Clinical Trial, Multicenter Study, Pelvic Drainage
- Trial name
- GRECCAR 5 (NCT01269567)
- Testing
- Laying and management of the drain (strictly randomized arm with drainage), No pelvic drainage
- Where
- 22 sites in France
- Volunteers
- 494 people
- Sponsor
- University Hospital, Bordeaux
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Gastrointestinal Dysfunction, Cardiac Surgery Intensive Care Treatment
Prognosis and Diagnosis of Acute Gastrointestinal Dysfunction in Cardiac Surgery Patients
The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients.
- Conditions
- Gastrointestinal Dysfunction, Cardiac Surgery Intensive Care Treatment, Cardiac Surgery, Cardiac Surgery in Adult Patient
- Trial name
- PREDICT-GICS (NCT07422246)
- Testing
- additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Oncologic Surgery, Gastrointestinal Cancers
Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery
After gastrointestinal or oncology surgery, it can be difficult to determine when a patient is ready to safely begin early rehabilitation or move toward discharge.
- Trial name
- DESIRE (NCT07406269)
- Testing
- DESIRE: AI-Based Clinical Decision Support for Postoperative Rehabilitation Planning
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Gastrointestinal Surgery
easyEndoTM Lite Stapler Study
The purpose of this observational study is to evaluate the safety and performance of the easyEndoTM Lite Linear Cutting Stapler and staggered design Loading Unit from EziSurg Medical in gastrointestinal surgery.
- Trial name
- NCT07361939
- Testing
- easyEndoTM Lite Linear Cutting Stapler and staggered design Loading Unit
- Where
- Lebanon
- Volunteers
- 156 people
- Sponsor
- Ezisurg Medical Co. Ltd.
Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery
This study is a clinical research project conducted at Xijing Hospital to compare the effects of two different neuromuscular blockade reversal strategies on the recovery of gastrointestinal (GI) function after colorectal surgery.
- Conditions
- Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus, Colorectal Surgery
- Trial name
- NCT07271875
- Testing
- Neostigmine + Atropine, Sugammadex
- Volunteers
- 560 people
- Sponsor
- Xijing Hospital
Obesity, Morbid Obesity
Comparing Dumping Symptoms and Quality of Life 6 Months After Sleeve Gastrectomy With or Without Transit Bipartition in Adults With Obesity
This clinical study aims to compare two types of bariatric (weight loss) surgery used to treat obesity: sleeve gastrectomy alone and sleeve gastrectomy with transit bipartition.
- Conditions
- Obesity, Morbid Obesity, Dumping Syndrome, Postgastrectomy Syndrome
- Trial name
- STuD-QoL (NCT07263269)
- Testing
- Sleeve Gastrectomy, Sleeve Gastrectomy with Transit Bipartition
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mina Kamal Gergis Erian
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)