Clinical trials: Gastrointestinal Surgery
Colorectal Cancer, Rectal Bleeding
Desmopressin (DDAVP) in Patients With Colorectal Cancer and Rectal Bleeding
The objective of this study is to find the maximum tolerated dose and preliminary efficacy of desmopressin as an haemostatic agent, when is administered to patients with colorectal cancer and rectal bleeding, before specific…
- Trial name
- NCT01623206
- Testing
- Desmopressin
- Where
- 2 sites in Argentina
- Volunteers
- 30 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
Gastrointestinal Neoplasms, Postoperative Complications
The Impact of Low Calorie and Low Nitrogen Parenteral Nutrition Support on the Clinical Outcome of Postoperative Patients
The study is designed to investigate the influence of parenteral nutrition (PN) with low nitrogen and calorie supply on the clinical outcome of patients after an operation compared to that of traditional PNs.
- Trial name
- NCT00247338
- Testing
- low calorie, low nitrogen parenteral nutrition for patient with NRS score 3
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Sino-Swed Pharmaceutical Corporation
Pancreatic Cancer
Immunotherapy Study for Surgically Resected Pancreatic Cancer
The purpose of this study is to assess overall survival after treatment with a regimen of adjuvant therapy (Gemcitabine alone or with 5-FU chemoradiation) with or without HyperAcute®-Pancreas (algenpantucel-L) immunotherapy in…
- Trial name
- NCT01072981
- Testing
- HyperAcute-Pancreas Immunotherapy, Gemcitabine, 5FU Chemoradiation
- Where
- 75 sites in United States
- Volunteers
- 722 people
- Sponsor
- NewLink Genetics Corporation
Non-alcoholic Steatohepatitis, Chronic Liver Disease
Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures
The purpose of this study is to assess the ability of eltrombopag to elevate platelet counts thereby reducing the need for platelet transfusions in chronic liver disease patients with thrombocytopenia undergoing elective invasive…
- Conditions
- Non-alcoholic Steatohepatitis, Chronic Liver Disease, HCV, NASH - Nonalcoholic Steatohepatitis
- Trial name
- ELEVATE (NCT00678587)
- Testing
- Eltrombopag
- Where
- 107 sites in United States, Argentina and 11 more
- Volunteers
- 292 people
- Sponsor
- GlaxoSmithKline
Hepatitis C
WEUSKOP5410: Observational Study in ENABLE Clinical Trials
Hepatitis C Virus (HCV) is a leading cause of chronic liver disease (CLD) worldwide. Current mainstay of treatment is combination therapy with pegylated interferon and ribavarin.
- Trial name
- NCT01458080
- Testing
- eltrombopag
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Rectal Cancer Surgery
ColoSeal™ ICD System Anastomotic Protection Pivotal Study
The purpose of this clinical investigation is to evaluate the safety of the ColoSeal ICD System by evaluating its effectiveness in reducing the stoma creation rate and by comparing the rate of major complications to current…
- Trial name
- NCT07429110
- Testing
- ColoSeal ICD System, Protective Diverting Ostomy
- Where
- 9 sites in United States, New Zealand
- Volunteers
- 250 people
- Sponsor
- Averto Medical, Inc.
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the relative merits, safety and effectiveness of transoral incisionless fundoplication (TIF) in proton pump inhibitor (PPI) dependent GERD patients compared with sham procedure.
- Trial name
- NCT01110811
- Testing
- Transoral Incisionless Fundoplication (TIF)
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 60 people
- Sponsor
- EndoGastric Solutions
Pancreatic Diseases, Bile Duct Diseases
SpyGlass Surgical Study
To document the clinical utility of diagnostic and/or therapeutic intraoperative endoscopy using a thin, single-use, flexible cholangiopancreatoscope To identify specific surgical procedures in which intraoperative use of a thin…
- Conditions
- Pancreatic Diseases, Bile Duct Diseases, Hepatic Disease
- Trial name
- NCT05822635
- Testing
- SpyGlass Discover Digital System or SpyGlass DS Direct Visualization System
- Where
- 5 sites in United States, China and 2 more
- Volunteers
- 34 people
- Sponsor
- Boston Scientific Corporation
Rectal Tumors
Effectiveness and Tolerability of an Oral Nutritional Supplement (PreOP Booster) Given Before Surgery
The aim of this pilot study is to investigate effectiveness, tolerability and safety of an oral nutritional supplement (PreOP Booster), given to rectal tumour patients prior to low anterior resection.
- Trial name
- NCT00730808
- Testing
- PreOP Booster (food for special medical purposes)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Fresenius Kabi
Nutritional Status, Malnutrition
Nutrition Insights Day Asia
This is an observational, cross-sectional study to be conducted on the Nutrition Insights Day (NID), with retrospective review of patient medical charts. No prospective follow-up period is considered.
- Conditions
- Nutritional Status, Malnutrition, Caloric Deficit, Protein Deficiency
- Trial name
- NCT03606603
- Where
- 89 sites in India, Indonesia and 5 more
- Volunteers
- 590 people
- Sponsor
- Fresenius Kabi
Elective Surgical Procedures, Digestive System
Seal-G Safety Study
The purpose of this study is to farther assess the safety of the Seal-G Surgical Sealant for the reinforcement and protection of gastrointestinal anastomosis.
- Trial name
- NCT02825173
- Testing
- Seal-G
- Where
- 3 sites in Israel, Italy
- Volunteers
- 20 people
- Sponsor
- Sealantis Ltd.
Pancreatic Cancer
Trial of Pemetrexed for Patients With Pancreatic Cancer Which Cannot be Treated With Surgery or is Metastatic
This study with pemetrexed is for patients with metastatic or unresectable pancreatic cancer who progressed after first line chemotherapy with gemcitabine.
- Trial name
- NCT00490373
- Testing
- pemetrexed
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Eli Lilly and Company