Clinical trials: Gastrointestinal Tumor Surgery
Esophagus Cancer
Chemotherapy With or Without Surgical Resection in Locally Advanced Esophageal Cancer
In this randomized study, we plan to address the important question of optimum local treatment for patients with localized esophageal cancer.
- Trial name
- NCT00193141
- Testing
- Paclitaxel, Carboplatin, 5-Fluorouracil
- Volunteers
- 200 people
- Sponsor
- SCRI Development Innovations, LLC
Gastric Adenocarcinoma, Oligometastasis
Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer
This phase II trial studies how well chemotherapy with or without radiation or surgery works in treating participants with esophageal or gastric cancer that has spread to less than 3 places in the body (oligometastatic).
- Conditions
- Gastric Adenocarcinoma, Oligometastasis, Stage IV Esophageal Adenocarcinoma AJCC v7, Stage IV Esophageal Cancer AJCC v7
- Trial name
- NCT03161522
- Testing
- Capecitabine, Chemotherapy, Conventional Surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
IPMN, Pancreatic, Pancreatic Cancer, Resected
Venous Resection in Patients Undergoing Pancreatic Surgery
Pancreatic surgery is the only treatment in the multimodality approach to pancreatic cancer sine qua non long-term survival cannot be achieved.
- Conditions
- IPMN, Pancreatic, Pancreatic Cancer, Resected, Pancreatic Cancer Borderline, Chronic Pancreatitis
- Trial name
- VENUS (NCT07621029)
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 1,000 people
- Sponsor
- Sahlgrenska University Hospital
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Spinal Stenosis, Disc Herniation
Effects of Cognitive Intervention Therapy on Postoperative Delirium
This study is a prospective, single-center, randomized controlled trial to compare whether applying cognitive intervention therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery…
- Conditions
- Spinal Stenosis, Disc Herniation, Lung Neoplasms, Carcinoma, Hepatocellular
- Trial name
- NCT06178939
- Testing
- control group, intervention group
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Pancreatic Cancer
Gemcitabine, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- SCALOP (NCT01032057)
- Testing
- capecitabine, gemcitabine hydrochloride, quality-of-life assessment
- Where
- 26 sites in United Kingdom
- Volunteers
- 114 people
- Sponsor
- Lisette Nixon
Anxiety, Fear
Therapeutic Listening in Patients With Colorectal Cancer
This is a randomized clinical trial that aims to investigate the effect of therapeutic listening anxiety and preoperative fear of patients hospitalized for surgical treatment of colorectal cancer.
- Trial name
- NCT02455128
- Testing
- Therapeutic listening
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Colorectal Tumor
Study of the Relationship Between Clinical and Paraclinical Markers During Situations of Cachexia and Pre-cachexia in Patients Over 70 Years With Colorectal Surgery
Cachexia associated with cancer is a grave and most of the time irreversible common situation. It seems independent from the size of the tumor or from its metastatic character.
- Trial name
- ANC2 (NCT02199912)
- Testing
- Biopsy of adipose and muscular tissue, Blood sampling, Calorimetry
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Carcinoma
Comparative Study of Cetuximab and Radiation Vs Surgery Before or After Radiation in Patients With Colorectal Carcinoma
RATIONALE: Monoclonal antibodies, such as Cetuximab, can target tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.This is an anti-cancer drug which has already been approved…
- Trial name
- NCT00725400
- Testing
- Cetuximab and Radiation Therapy, Surgery and Radiation Therapy
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- American Scitech International
Colorectal Cancer, Colon Rectal Resection
Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer
Study of Oxidative stress Markers (F2 Isoprostanes for lipid peroxidation, Carbonyl groups for protein peroxidation, 3 Nitrotyrosine for damage by nitrogens, and 8-Hydroxyguanosine for RNA peroxidation)in patients with colorectal…
- Conditions
- Colorectal Cancer, Colon Rectal Resection, Oxidative Stress
- Trial name
- NCT01470586
- Testing
- Surgery for colorectal cancer
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. Hatzikosta General Hospital
Colorectal Carcinomatosis
Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis French Part of the Main Bev-IP Study
Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC).
- Trial name
- NCT03161041
- Testing
- Cytoreductive surgery combined with HIPEC, bevacizumab and HIPEC (Oxaliplatin 360 mg/m2).
- Sponsor
- Hospices Civils de Lyon
Cholecystitis, Perforated Duodenal Ulcer
Incentive Spirometry and Upper Abdominal Laparoscopic Surgery
To compare the effects of volume-oriented versus flow-oriented incentive spirometry on pulmonary function tests and functional capacity in patients of upper abdominal laparoscopic surgery.
- Conditions
- Cholecystitis, Perforated Duodenal Ulcer, Diaphragmatic Hernia, Benign Pancreas Tumor
- Trial name
- NCT04716166
- Testing
- Volume-oriented incentive spirometry, Flow-oriented incentive spirometry
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Colorectal Cancer
Gut Microbiome Modification Through Dietary Intervention in Patients With Colorectal Cancer: Response to Surgery
The investigators will conduct an open, controlled, randomized clinical trial, in patients with scheduled surgical intervention for CRC in the General Surgery and Digestive System Unit of the Virgen de la Arrixaca University…
- Trial name
- NCT04869956
- Testing
- Dietary pattern : High-fiber diet rich in PUFA, Dietary pattern: Standard diet
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Lung Cancer, Esophageal Cancer
NIR Fluorescence Imaging Technique in Thoracic Surgery With ICG
This study aims to first apply near-infrared fluorescence imaging technology in thoracic surgery with indocyanine green in China.
- Trial name
- NCT02611245
- Testing
- Indocyanine green
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Chinese Academy of Sciences
Colorectal Cancer
Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00114231
- Testing
- capecitabine, oxaliplatin, neoadjuvant therapy
- Where
- 67 sites in United States
- Volunteers
- 90 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colonic Cancer
Abdominal Massage After Colon Surgery for Cancer
Postoperative ileus is a transient gastrointestinal dysmotility following abdominal surgery that leads to bloating, abdominal distention, visceral pain, nausea, vomiting, and delayed passage of flatus and stool.
- Trial name
- MATRAC_Ter (NCT07713472)
- Testing
- ABDOMINAL MASSAGE, Usual physiotherapeutic intervention
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Grenoble
Liver Metastasis Colon Cancer
Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant
The hypothesis is that liver venous deprivation (LVD) could strongly improve hypertrophy of the future remnant liver (FRL) at 3 weeks, as compared to portal vein embolization (PVE) in patient with liver metastases from…
- Trial name
- HYPER-LIV01 (NCT03841305)
- Testing
- Liver preparation before major hepatectomy
- Where
- 12 sites in France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Colonic Neoplasms
Five Year Oncological Outcome After CME for Right-sided Colon Cancer
Study based on existing databases investigating the causal oncological treatment effects of complete mesocolic excision on UICC stage I-III right-sided colon cancer.
- Trial name
- NCT03754075
- Testing
- Complete mesocolic excision, Conventional colon resections
- Volunteers
- 1,069 people
- Sponsor
- Nordsjaellands Hospital
Liver Metastases, Recurrent Colon Cancer
Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer
This phase II trial studies how well giving combination chemotherapy and bevacizumab before surgery and radiolabeled monoclonal antibody therapy works in treating liver metastases in patients with metastatic colorectal cancer.
- Conditions
- Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer
- Trial name
- NCT01320683
- Testing
- oxaliplatin, leucovorin calcium, fluorouracil
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- City of Hope Medical Center
Enhanced Recovery After Surgery, Multimodal Analgesia
Enhanced Recovery After Surgery-Based Multimodal Preemptive Analgesia for Perioperative Management in Transarterial Chemoembolization of Intermediate-to-Advanced Hepatocellular Carcinoma
To evaluate the effectiveness of the combination of hydrochloride hydromorphone and flurbiprofen ester for post-TACE intravenous patient-controlled intravenous analgesia (PCIA).
- Conditions
- Enhanced Recovery After Surgery, Multimodal Analgesia, Real-world Study, Transarterial Chemoembolization
- Trial name
- NCT07315022
- Testing
- hydrochloride hydromorphone + flurbiprofen axetil, conventional analgesia
- Where
- China
- Volunteers
- 129 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
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